Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Deborah Palliser"'
Publikováno v:
Molecular Genetics and Metabolism. 132:S46
Autor:
Keith E. Maier, Deborah Palliser, Gayatri Mukherjee, Samantha E. Wilner, Joseph A. Katakowski, Michael Travis Harrison, Matthew Levy, Teresa P. DiLorenzo
Publikováno v:
Molecular Therapy
Due to their ability to knock down the expression of any gene, siRNAs have been heralded as ideal candidates for treating a wide variety of diseases, including those involving "undruggable" targets. However, the therapeutic potential of siRNAs remain
Autor:
Matthew Levy, Amy Yan, Linsley Kelly, Na Li, Andrew D. Ellington, Raquel Furtado, Michelle Byrom, Maria de Lourdes Borba Magalhães, Deborah Palliser
Publikováno v:
Molecular Therapy
We have developed a selection scheme to generate nucleic acid sequences that recognize and directly internalize into mammalian cells without the aid of conventional delivery methods. To demonstrate the generality of the technology, two independent se
Autor:
Kartik Chandran, Heriberto Lima, Stefan M Muehlbauer, Michael P. Lisanti, David L. Goldman, Jürgen Brojatsch, Raquel Furtado, Deborah Palliser, Lee S. Jacobson
Necrotic cell death triggers a range of biological responses including a strong adaptive immune response, yet we know little about the cellular pathways that control necrotic cell death. Inhibitor studies suggest that proteases, and in particular cat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93e762f5029e418dc4c01fa96e1998c4
https://europepmc.org/articles/PMC4614982/
https://europepmc.org/articles/PMC4614982/
Autor:
Matthew Levy, Deborah Palliser
Publikováno v:
Biomaterials in Regenerative Medicine and the Immune System ISBN: 9783319180441
Dendritic cells (DCs) are attractive targets for therapies aimed at enhancing or diminishing immunity. The delivery of antigens to DCs can effectively modify antigen-specific T cell responses and provides a strategy for enhancing vaccines which requi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1db522a40e40fd4b0af5f2e957607964
https://doi.org/10.1007/978-3-319-18045-8_11
https://doi.org/10.1007/978-3-319-18045-8_11
Autor:
Deborah Palliser, Roderick T. Bronson, Judy Lieberman, Dipanjan Chowdhury, David M. Knipe, Qing Yin Wang, Sandra J. Lee
Publikováno v:
Nature. 439:89-94
Herpes simplex virus 2 (HSV-2) infection causes significant morbidity and is an important cofactor for the transmission of HIV infection. A microbicide to prevent sexual transmission of HSV-2 would contribute substantially to controlling the spread o
Publikováno v:
The Journal of Immunology. 174:1879-1887
Soluble heat shock fusion proteins (Hsfp) stimulate mice to produce CD8+ CTL, indicating that these proteins are cross-presented by dendritic cells (DC) to naive CD8 T cells. We report that cross-presentation of these proteins depends upon their bind
Autor:
Steven P. Lamontagne, Qian Huang, Herman N. Eisen, Nir Hacohen, Richard A. Young, Deborah Palliser, Eduardo Guillen
Publikováno v:
The Journal of Immunology. 172:2885-2893
Recombinant heat shock fusion proteins (Hsfp) injected into mice without added adjuvants can stimulate production of CD8 cytolytic T cells. Because initiation of productive immune responses generally requires dendritic cell (DC) activation, the quest
Publikováno v:
Proceedings of the National Academy of Sciences. 99:2983-2988
Naïve T cells do not proliferate in normal individuals in the absence of antigen stimulation, but they proliferate spontaneously when T cells are severely depleted. We show here that coculture of syngeneic dendritic cells (DC) with naïve T cells ex
Autor:
Colm J. Ryan, Assen Roguev, Hyun-Soo Kim, Sonja Schaetzlein, Michael Shales, Joseph A. Katakowski, Michael-Christopher Keogh, Winfried Edelmann, Nevan J. Krogan, Elena Tosti, Deborah Palliser
Publikováno v:
Krogan, Nevan; Tosti, E; Katakowski, JA; Schaetzlein, S; Kim, HS; Ryan, CJ; et al.(2014). Evolutionarily conserved genetic interactions with budding and fission yeast MutS identify orthologous relationships in mismatch repair-deficient cancer cells. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/46h6896r
Genome Medicine
Genome Medicine
Background The evolutionarily conserved DNA mismatch repair (MMR) system corrects base-substitution and insertion-deletion mutations generated during erroneous replication. The mutation or inactivation of many MMR factors strongly predisposes to canc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::033588685eee8d754aa0a94f91ba91fc
http://www.escholarship.org/uc/item/46h6896r
http://www.escholarship.org/uc/item/46h6896r