Zobrazeno 1 - 10
of 394
pro vyhledávání: '"Deborah P M, Symmons"'
Autor:
Yi Pan, Sam Norton, James M Gwinnutt, Lianne Kearsley-Fleet, Deborah P M Symmons, Mark Lunt, Adam Young, BSRBR-RA Control Centre Consortium, Kimme L Hyrich, Suzanne M M Verstappen
Publikováno v:
PLoS ONE, Vol 15, Iss 4, p e0231481 (2020)
[This corrects the article DOI: 10.1371/journal.pone.0215999.].
Externí odkaz:
https://doaj.org/article/0d643b48cd2145b189e34f65926e511a
Autor:
Jamie C. Sergeant, Kimme L. Hyrich, James Anderson, Kamilla Kopec-Harding, Holly F. Hope, Deborah P. M. Symmons, RAMS Co-Investigators, Anne Barton, Suzanne M. M. Verstappen
Publikováno v:
Arthritis Research & Therapy, Vol 20, Iss 1, Pp 1-11 (2018)
Abstract Background Methotrexate (MTX) remains the disease-modifying anti-rheumatic drug of first choice in rheumatoid arthritis (RA) but response varies. Predicting non-response to MTX could enable earlier access to alternative or additional medicat
Externí odkaz:
https://doaj.org/article/b9365c14a0254f469ffa9ea986a090ac
Autor:
James Bluett, Jamie C. Sergeant, Alex J. MacGregor, Jacqueline R. Chipping, Tarnya Marshall, Deborah P. M. Symmons, Suzanne M. M. Verstappen
Publikováno v:
Arthritis Research & Therapy, Vol 20, Iss 1, Pp 1-6 (2018)
Abstract Background Oral methotrexate (MTX) is the first-line therapy for patients with rheumatoid arthritis (RA). However, approximately one quarter of patients discontinue MTX within 12 months. MTX failure, defined as MTX cessation or the addition
Externí odkaz:
https://doaj.org/article/4f8bc3df3e154242ac352720058a130e
Autor:
Yi Pan, Sam Norton, James M Gwinnutt, Lianne Kearsley-Fleet, Deborah P M Symmons, Mark Lunt, Adam Young, BSRBR-RA Control Centre Consortium, Kimme L Hyrich, Suzanne M M Verstappen
Publikováno v:
PLoS ONE, Vol 14, Iss 5, p e0215999 (2019)
BackgroundUnited Kingdom guidelines for the use of biologic disease modifying anti-rheumatic drugs (bDMARDS) for rheumatoid arthritis (RA) require patients to have active disease (Disease Activity Score [DAS28] >5.1) and have failed ≥2 previous con
Externí odkaz:
https://doaj.org/article/707be9c941d04493be1e4a0aa4bd17c0
Autor:
Holly F Hope, George M Binkley, Sally Fenton, George D Kitas, Suzanne M M Verstappen, Deborah P M Symmons
Publikováno v:
PLoS ONE, Vol 14, Iss 1, p e0201196 (2019)
IntroductionPrevious research has shown that statin adherence for the primary prevention of CVD is lower compared to secondary prevention populations. Therefore the aim of this systematic review was to review predictors of statin adherence for the pr
Externí odkaz:
https://doaj.org/article/b9e166843f5a445f978005c623a910b9
Autor:
Deborah P M Symmons, James M. Gwinnutt
Publikováno v:
Oxford Textbook of Rheumatoid Arthritis
This chapter describes the incidence, prevalence, and mortality of rheumatoid arthritis (RA) in adult populations around the world. Studies can only be compared if they have used the same case definition. The characteristics of the 1987 American Coll
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::064e7dadab8a43ed3149441a0d867d7f
https://doi.org/10.1093/med/9780198831433.003.0003
https://doi.org/10.1093/med/9780198831433.003.0003
Autor:
P A Sanders, Kimme L Hyrich, Kath D. Watson, Bev Harrison, Deborah P M Symmons, Romela Benitha, Peter Klimiuk, Sheila O’Reilly, Nicola Maiden, Shane Clarke, Lianne Kearsley-Fleet, Ian Griffiths, David A. Walsh, Marwan Bukhari, Paul D. Thompson, Ernest Choy, Paul Emery, Rikki Abernethy, Hilary A Capell, Ronald Jubb, Susan Knight, Mark Lunt, Amanda Coulson, Rhian Mair Goodfellow, Tom Price, David Scott, Laura Chadwick, Nina Brown, Andrew Hassell, A J Taggart, Neil Hopkinson, Fiona McCrae, Ian N. Bruce, Sandra Green, Lesley Hordon, George D. Kitas, Kimme L. Hyrich, Duncan Porter
Publikováno v:
BSRBR-RA Control Centre Consortium 2019, ' Cervical screening uptake and rates of cervical dysplasia in the British Society for Rheumatology Biologics Register for Rheumatoid Arthritis ', Rheumatology (Oxford) . https://doi.org/10.1093/rheumatology/kez277
BSRBR-RA Control Centre Consortium 2019, ' Cervical screening uptake and rates of cervical dysplasia in the British Society for Rheumatology Biologics Register for Rheumatoid Arthritis ', Rheumatology (Oxford, England) . https://doi.org/10.1093/rheumatology/kez277
BSRBR-RA Control Centre Consortium 2019, ' Cervical screening uptake and rates of cervical dysplasia in the British Society for Rheumatology Biologics Register for Rheumatoid Arthritis ', Rheumatology (Oxford, England) . https://doi.org/10.1093/rheumatology/kez277
Objectives To compare cervical screening attendance and cytology (high- and low-grade cervical dysplasia [HGCD and LGCD]) between women with RA and the English general population and between biologic DMARD (bDMARD)-naïve and exposed women. Methods T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::393fbccc224cacdea428269ea645c5b0
https://research.manchester.ac.uk/en/publications/74caffc6-71d5-4054-9c91-8d6e8426008d
https://research.manchester.ac.uk/en/publications/74caffc6-71d5-4054-9c91-8d6e8426008d
Autor:
Kim Overvad, Asta Linauskas, Martin Berg Johansen, Annette de Thurah, Kristian Stengaard-Pedersen, Deborah P M Symmons
Publikováno v:
Linauskas, A, Overvad, K, Symmons, D, Johansen, M B, Stengaard-Pedersen, K & de Thurah, A 2019, ' Body fat percentage, waist circumference and obesity as risk factors for rheumatoid arthritis-A Danish cohort study ', Arthritis Care & Research, vol. 71, no. 6, pp. 777-786 . https://doi.org/10.1002/acr.23694
Linauskas, A, Overvad, K, Symmons, D, Johansen, M B, Stengaard-pedersen, K & De Thurah, A 2018, ' Body fat percentage, waist circumference and obesity as risk factors for rheumatoid arthritis-A Danish cohort study ', Arthritis Care & Research . https://doi.org/10.1002/acr.23694
Linauskas, A, Overvad, K, Symmons, D, Johansen, M B, Stengaard-Pedersen, K & de Thurah, A 2019, ' Body fat percentage, waist circumference and obesity as risk factors for rheumatoid arthritis : A Danish cohort study ', Arthritis Care & Research, vol. 71, no. 6, pp. 777-786 . https://doi.org/10.1002/acr.23694
Linauskas, A, Overvad, K, Symmons, D, Johansen, M B, Stengaard-pedersen, K & De Thurah, A 2018, ' Body fat percentage, waist circumference and obesity as risk factors for rheumatoid arthritis-A Danish cohort study ', Arthritis Care & Research . https://doi.org/10.1002/acr.23694
Linauskas, A, Overvad, K, Symmons, D, Johansen, M B, Stengaard-Pedersen, K & de Thurah, A 2019, ' Body fat percentage, waist circumference and obesity as risk factors for rheumatoid arthritis : A Danish cohort study ', Arthritis Care & Research, vol. 71, no. 6, pp. 777-786 . https://doi.org/10.1002/acr.23694
Objective: To investigate the relationship between bioimpedance-derived total body fat percentage, waist circumference, and body mass index (BMI) and the subsequent development of rheumatoid arthritis (RA). Methods: A population-based prospective coh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f5875059b7e400d1d2c1a596e77f676
https://vbn.aau.dk/da/publications/b68b7336-f327-4bc9-8e48-79932b240577
https://vbn.aau.dk/da/publications/b68b7336-f327-4bc9-8e48-79932b240577
Autor:
Deborah P M Symmons, Jon Packham, Lianne Kearsley-Fleet, Kath D. Watson, Louise K. Mercer, Karen M Fagerli, Kimme L. Hyrich
Publikováno v:
Fagerli, K M, Kearsley-Fleet, L, Mercer, L K, Watson, K, Packham, J, Symmons, D P M, Hyrich, K L & British Society for Rheumatology Biologics Register 2019, ' Malignancy and mortality rates in patients with severe psoriatic arthritis requiring tumour-necrosis factor alpha inhibition: results from the British Society for Rheumatology Biologics Register ', Rheumatology (Oxford, England), vol. 58, no. 1, pp. 80-85 . https://doi.org/10.1093/rheumatology/key241
Rheumatology (Oxford, England)
Rheumatology (Oxford, England)
Objective: The aim of this study was to compare the incidence of cancer and all-cause and cause-specific mortality rates among a cohort of patients with severe PsA receiving TNF inhibitor (TNFi) with those of the general UK population.Methods: Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a63b646c03ead24508e84b80b25736af
https://research.manchester.ac.uk/en/publications/b8eb5210-6ecc-4fd8-ba0c-2074bb40d8ca
https://research.manchester.ac.uk/en/publications/b8eb5210-6ecc-4fd8-ba0c-2074bb40d8ca
Autor:
Mark Lunt, Kath D. Watson, Lianne Kearsley-Fleet, Mari Kihara, Kimme L. Hyrich, Rebecca Davies, Deborah P M Symmons
Publikováno v:
Clinical Rheumatology
Kihara, M, Davies, R, Kearsley-Fleet, L, Watson, K, Lunt, M, Symmons, D & Hyrich, K 2017, ' Use and effectiveness of tocilizumab among patients with rheumatoid arthritis: An observational study from the British Society for Rheumatology Biologics Register for Rheumatoid Arthritis ', Clinical Rheumatology, vol. 36, no. 2, pp. 241-250 . https://doi.org/10.1007/s10067-016-3485-5
Kihara, M, Davies, R, Kearsley-Fleet, L, Watson, K, Lunt, M, Symmons, D & Hyrich, K 2017, ' Use and effectiveness of tocilizumab among patients with rheumatoid arthritis: An observational study from the British Society for Rheumatology Biologics Register for Rheumatoid Arthritis ', Clinical Rheumatology, vol. 36, no. 2, pp. 241-250 . https://doi.org/10.1007/s10067-016-3485-5
The aims of the present study are to describe the characteristics of rheumatoid arthritis (RA) patients selected for tocilizumab (TCZ), compare the “real-world” effectiveness of TCZ and tumour necrosis factor inhibitors (TNFi) when used as a firs