Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Deborah Morosini"'
Autor:
Norma A. Palma, Siraj M. Ali, Jamie O'Connor, Deepa Dutta, Kai Wang, Salil Soman, Gary A. Palmer, Deborah Morosini, Jeffrey S. Ross, Doron Lipson, Phil J. Stephens, Mayur Patel, Vincent A. Miller, Nicholas Koutrelakos
Publikováno v:
Case Reports in Oncology, Vol 7, Iss 2, Pp 503-508 (2014)
Background: Carcinoma of unknown primary (CUP) accounts for 3-5% of all adult solid tumors. An extensive search for the anatomic site of origin is often undertaken in an attempt to tailor systemic treatment, but the latter often has limited efficacy
Externí odkaz:
https://doaj.org/article/c3e9468f60934015a6cc8287ab076e87
Autor:
Christine M. Lovly, Siraj M. Ali, Vincent A. Miller, Philip J. Stephens, Jeffrey S. Ross, Deborah Morosini, Jens Meiler, Jonathan H. Sheehan, Yingjun Yan, Heidi Chen, Andrew Whiteley, Tiziana Vavalà, Beth Eaby-Sandy, Satyanarayan K. Reddy, Suresh S. Ramalingam, Vijay Peddareddigari, Taofeek K. Owonikoko, Eiki Ichihara, Kyle Gowen, Barbara J. Gitlitz, Francis J. Giles, Young Kwang Chae, Jean-Nicolas Gallant, Kartik Konduri
Supplementary Methods, Supplementary References, Supplementary Table Legends, and Supplementary Figure Legends.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d5ff55dd2169cc77c991bc6bb6e3dc5
https://doi.org/10.1158/2159-8290.22531335
https://doi.org/10.1158/2159-8290.22531335
Autor:
Christine M. Lovly, Siraj M. Ali, Vincent A. Miller, Philip J. Stephens, Jeffrey S. Ross, Deborah Morosini, Jens Meiler, Jonathan H. Sheehan, Yingjun Yan, Heidi Chen, Andrew Whiteley, Tiziana Vavalà, Beth Eaby-Sandy, Satyanarayan K. Reddy, Suresh S. Ramalingam, Vijay Peddareddigari, Taofeek K. Owonikoko, Eiki Ichihara, Kyle Gowen, Barbara J. Gitlitz, Francis J. Giles, Young Kwang Chae, Jean-Nicolas Gallant, Kartik Konduri
Supplementary Tables S1 - S3. Supplementary Table S1. Summary of EGFR alterations in NSCLC identified by FoundationOne. Supplementary Table S2. Summary of genomic coordinates for the kinase fusions identified in this study. Supplementary Table S3. Re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db98bc3806deffc1adf56b29743aafdf
https://doi.org/10.1158/2159-8290.22531332
https://doi.org/10.1158/2159-8290.22531332
Autor:
Jennifer A. Low, Nisha Nanda, Michele Fernandes, Brian B. Tuch, Deborah Morosini, Philip J. Stephens, Yali Li, Dara L. Aisner, Marileila Varella-Garcia, Antonio Jimeno, Stephen Keysar, Adriana Estrada-Bernal, Anh T. Le, Aria Vaishnavi, Lara E. Davis, Robert C. Doebele
Supplementary Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36a66340cae723397120cc48c8d7507e
https://doi.org/10.1158/2159-8290.22529550.v1
https://doi.org/10.1158/2159-8290.22529550.v1
Autor:
Jennifer A. Low, Nisha Nanda, Michele Fernandes, Brian B. Tuch, Deborah Morosini, Philip J. Stephens, Yali Li, Dara L. Aisner, Marileila Varella-Garcia, Antonio Jimeno, Stephen Keysar, Adriana Estrada-Bernal, Anh T. Le, Aria Vaishnavi, Lara E. Davis, Robert C. Doebele
Supplementary Figure 1. Structure of LOXO-101. Supplementary Figure 2. Schematic for TRK-SHC1 proximity ligation assay (PLA). Supplementary Figure 3. Validation of the TRK-SHC1 PLA. Supplementary Figure 4. TRK and ALK PLA in an ALK+ tumor sample. Sup
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2127ca5310438ad8be46daccfdd01122
https://doi.org/10.1158/2159-8290.22529547.v1
https://doi.org/10.1158/2159-8290.22529547.v1
Autor:
Christine M. Lovly, Siraj M. Ali, Vincent A. Miller, Philip J. Stephens, Jeffrey S. Ross, Deborah Morosini, Jens Meiler, Jonathan H. Sheehan, Yingjun Yan, Heidi Chen, Andrew Whiteley, Tiziana Vavalà, Beth Eaby-Sandy, Satyanarayan K. Reddy, Suresh S. Ramalingam, Vijay Peddareddigari, Taofeek K. Owonikoko, Eiki Ichihara, Kyle Gowen, Barbara J. Gitlitz, Francis J. Giles, Young Kwang Chae, Jean-Nicolas Gallant, Kartik Konduri
Supplementary Figures S1 - S10. Supplementary Figure S1. Additional information for Patient 1. Supplementary Figure S2. Additional information for Patient 2. Supplementary Figure S3. Additional information for Patient 3. Supplementary Figure S4. Addi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48e88c6e94da7f5cc24a334b865d42c6
https://doi.org/10.1158/2159-8290.22531338.v1
https://doi.org/10.1158/2159-8290.22531338.v1
Autor:
Vincent A. Miller, Philip J. Stephens, Malte Peters, Eric Collisson, Jeffrey S. Ross, Deborah Morosini, Roman Yelensky, Doron Lipson, Robert Schlegel, Joel Greshock, Jared White, Steven Roels, Eric M. Sanford, Caitlin McMahon, Depinder Khaira, Adrienne Johnson, Joel Greenbowe, Kyle A. Gowen, Alex Fichtenholtz, Rachel Erlich, Julia A. Elvin, Alan Huang, Savina Jaeger, Zachary R. Chalmers, Tim Brennan, Ravi Salgia, Sai-Hong Ignatius Ou, Rick Hoover, David Jentz, Carrie Lee, Jose A. Bufill, Mikhail Akimov, Todd M. Bauer, Xinyuan Lu, Juliann Chmielecki, Mark Rosenzweig, Siraj M. Ali, Garrett M. Frampton
Genomic alterations in lung adenocarcinoma displayed in Figure 2A.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bef9595be8a039a3d2c2847080d6e54
https://doi.org/10.1158/2159-8290.22530219.v1
https://doi.org/10.1158/2159-8290.22530219.v1
Autor:
Vincent A. Miller, Philip J. Stephens, Malte Peters, Eric Collisson, Jeffrey S. Ross, Deborah Morosini, Roman Yelensky, Doron Lipson, Robert Schlegel, Joel Greshock, Jared White, Steven Roels, Eric M. Sanford, Caitlin McMahon, Depinder Khaira, Adrienne Johnson, Joel Greenbowe, Kyle A. Gowen, Alex Fichtenholtz, Rachel Erlich, Julia A. Elvin, Alan Huang, Savina Jaeger, Zachary R. Chalmers, Tim Brennan, Ravi Salgia, Sai-Hong Ignatius Ou, Rick Hoover, David Jentz, Carrie Lee, Jose A. Bufill, Mikhail Akimov, Todd M. Bauer, Xinyuan Lu, Juliann Chmielecki, Mark Rosenzweig, Siraj M. Ali, Garrett M. Frampton
Focal amplification and activating point mutation of the MET gene are well-characterized oncogenic drivers that confer susceptibility to targeted MET inhibitors. Recurrent somatic splice site alterations at MET exon 14 (METex14) that result in exon s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e45f91fabb778931c2686fc61c7ae60
https://doi.org/10.1158/2159-8290.c.6546132.v1
https://doi.org/10.1158/2159-8290.c.6546132.v1
Autor:
Meredith A. Morgan, Theodore S. Lawrence, Jonathan Maybaum, Sonya D. Zabludoff, Jeffrey L. Brown, Deborah Morosini, Diane M. Simeone, Linda Hylander-Gans, Joshua D. Parsels, Sankari Arumugarajah, Maria C. Hassan, Lili Zhao, Marisa Gross, Daria M. Tanska, Yushen Qian, Leslie A. Parsels
Purpose: Chk1 inhibitors, such as AZD7762, are in clinical development in combination with cytotoxic agents for the treatment of solid tumors, including pancreatic cancers. To maximize the likelihood of their clinical success, it is essential to opti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d413ee72b358ad1b032e8eeb53cf44e
https://doi.org/10.1158/1078-0432.c.6518984.v1
https://doi.org/10.1158/1078-0432.c.6518984.v1
Autor:
Meredith A. Morgan, Theodore S. Lawrence, Jonathan Maybaum, Sonya D. Zabludoff, Jeffrey L. Brown, Deborah Morosini, Diane M. Simeone, Linda Hylander-Gans, Joshua D. Parsels, Sankari Arumugarajah, Maria C. Hassan, Lili Zhao, Marisa Gross, Daria M. Tanska, Yushen Qian, Leslie A. Parsels
Supplementary Figures S1-S5; Supplementary Tables S1-S2.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ca3b865e45fb076b0aefaa76589910f
https://doi.org/10.1158/1078-0432.22442177
https://doi.org/10.1158/1078-0432.22442177