Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Deborah Moore-Lai"'
Autor:
Zhen Liu, Wilson Guzman, Parker Johnson, Megan McLaughlin, Caitlin O’Toole, Magali Pederzoli-Ribeil, Huawei Qiu, Margaret Karow, Tim Clackson, Jennifer O’Neil, Ugur Eskiocak, Miso Park, Benjamin Nicholson, John C Williams, Kurt A Jenkins, Deborah Moore-Lai, Veronica Flesch, Ronan C O’Hagan, Ulrich Rodeck
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 12 (2023)
Introduction The clinical benefit of the anti-CTLA-4 monoclonal antibody (mAb) ipilimumab has been well established but limited by immune-related adverse events, especially when ipilimumab is used in combination with anti-PD-(L)1 mAb therapy. To over
Externí odkaz:
https://doaj.org/article/d160ab0121654c39a0d99d2106b97ef4
Autor:
Edwin C. Rowland, Deborah Moore-Lai
Publikováno v:
Journal of Parasitology. 90:85-91
Trypanosoma cruzi is the causative agent of Chagas disease, which is characterized by acute and chronic phases. During the former, parasitemia rises dramatically, then decreases significantly during the chronic phase. Immune mechanisms responsible fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7ce250f4e7c8eee686fbbd032da4038
https://doi.org/10.1645/ge-123r1
https://doi.org/10.1645/ge-123r1
Autor:
Deborah Moore-Lai, Ed Rowland
Publikováno v:
Journal of Parasitology. 90:893-895
Parasites have been shown to up- and downregulate host apoptosis, most likely facilitating their ability to successfully establish an infection in the host. It has been demonstrated that pathogens modulate well-established pathways, leading to cell d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d69d14a2cf8a2fd6a440c3a9e4b3b88
https://doi.org/10.1645/ge-146r
https://doi.org/10.1645/ge-146r
Autor:
Edwin C. Rowland, Deborah Moore-Lai
Publikováno v:
The Journal of parasitology. 90(3)
Trypanosoma cruzi, a protozoan parasite, is the etiologic agent of Chagas disease. The disease is characterized by acute and chronic phases, with high and low parasitemia, respectively. A strong immune activation is necessary for the host to enter th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::587a99aadc2b66f969232a19f0a3cd62
https://pubmed.ncbi.nlm.nih.gov/15270096
https://pubmed.ncbi.nlm.nih.gov/15270096
Publikováno v:
The Journal of parasitology. 89(5)
Dicationic compounds, which are derivatives of pentamidine, are being developed for use as antiprotozoal drugs. These compounds bind to the minor groove of DNA and are thought to inhibit DNA-dependent enzymes and thereby prevent cellular replication
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4245ddb05902e7ca28fb6e8dc5f91d32
https://pubmed.ncbi.nlm.nih.gov/14627166
https://pubmed.ncbi.nlm.nih.gov/14627166