Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Deborah M. Leonard"'
Autor:
Jack L Leonard, Deborah M Leonard, Scot A Wolfe, Jilin Liu, Jaime Rivera, Michelle Yang, Ryan T Leonard, Jacob P S Johnson, Prashant Kumar, Kate L Liebmann, Amanda A Tutto, Zhongming Mou, Karl J Simin
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0184458 (2017)
[This corrects the article DOI: 10.1371/journal.pone.0181724.].
Externí odkaz:
https://doaj.org/article/bbf9eb4f25cb452ba73c52962bc98659
Autor:
Jack L Leonard, Deborah M Leonard, Scot A Wolfe, Jilin Liu, Jaime Rivera, Michelle Yang, Ryan T Leonard, Jacob P S Johnson, Prashant Kumar, Kate L Liebmann, Amanda A Tutto, Zhongming Mou, Karl J Simin
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0181724 (2017)
Members of the Dickkopf (Dkk) family of Wnt antagonists interrupt Wnt-induced receptor assembly and participate in axial patterning and cell fate determination. One family member, DKK3, does not block Wnt receptor activation. Loss of Dkk3 expression
Externí odkaz:
https://doaj.org/article/314b504f6fa84f28abb31e68d7b35583
Autor:
Jenny Janusis, Rasika A. Rohatgi, Karl D. Bellve, Silvia Corvera, Kevin E. Fogarty, Eric H. Baehrecke, Leslie M. Shaw, Deborah M. Leonard
Publikováno v:
Oncogene
Beclin 1 is a haploinsufficient tumor suppressor that is decreased in many human tumors. The function of beclin 1 in cancer has been attributed primarily to its role in the degradative process of macroautophagy. However, beclin 1 is a core component
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c4d0cecbca5dedba91aebb8fd458eed
https://doi.org/10.1038/onc.2014.454
https://doi.org/10.1038/onc.2014.454
Autor:
Kate L. Liebmann, Jacob P. S. Johnson, Deborah M. Leonard, Michelle Yang, Karl Simin, Zhongming Mou, Amanda A. Tutto, Jack L. Leonard, Prashant Kumar, Scot A. Wolfe, Jilin Liu, Ryan T. Leonard, Jaime J. Rivera
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 7, p e0181724 (2017)
PLoS ONE, Vol 12, Iss 7, p e0181724 (2017)
Members of the Dickkopf (Dkk) family of Wnt antagonists interrupt Wnt-induced receptor assembly and participate in axial patterning and cell fate determination. One family member, DKK3, does not block Wnt receptor activation. Loss of Dkk3 expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22cb89975f131644ee23e292cf7c8fb6
https://pubmed.ncbi.nlm.nih.gov/28863194
https://pubmed.ncbi.nlm.nih.gov/28863194
Autor:
Evelyn A. Kurt-Jones, Christine A. St. Pierre, Robert W. Finberg, Deborah M. Leonard, Silvia Corvera
Publikováno v:
Experimental and Molecular Pathology. 91:723-732
Antibody-mediated intracellular delivery of therapeutic agents has been considered for treatment of a variety of diseases. These approaches involve targeting cell-surface receptor proteins expressed by tumors or viral proteins expressed on infected c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8502734d75eab45e55f3dba08473bd1
https://doi.org/10.1016/j.yexmp.2011.05.011
https://doi.org/10.1016/j.yexmp.2011.05.011
Publikováno v:
Biochemical Society Symposia. 74:95-105
The FYVE domain is an approx. 80 amino acid motif that binds to the phosphoinositide PtdIns3P with high specificity and affinity. It is present in 38 predicted gene products within the human genome, but only in 12–13 in Caenorhabditis elegans and D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e6f2b33f924a9ca3019c7eb5b0a8a55
https://doi.org/10.1042/bss2007c09
https://doi.org/10.1042/bss2007c09
Autor:
Silvia Corvera, Akira Hayakawa, Stephanie T. Murphy, Karl D. Bellve, Martha C. Soto, Clive Standley, Kevin E. Fogarty, Deborah M. Leonard, Susan J. Hayes, Craig C. Mello, David G. Lambright
Publikováno v:
Proceedings of the National Academy of Sciences. 103:11928-11933
The FYVE domain binds with high specificity and avidity to phosphatidylinositol 3-phosphate. It is present in ≈30 proteins in humans, some of which have been implicated in functions ranging from early endosome fusion to signal transduction through
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1182c95721a1a56a9a2086ba58959b1c
https://doi.org/10.1073/pnas.0508832103
https://doi.org/10.1073/pnas.0508832103
Autor:
Richard A. Tuft, Karl D. Bellve, Kevin E. Fogarty, Akira Hayakawa, Silvia Corvera, Lawrence M. Lifshitz, Clive Standley, Deborah M. Leonard
Publikováno v:
Journal of Biological Chemistry. 281:16139-16146
Clathrin assembly at the plasma membrane is a fundamental process required for endocytosis. In cultured cells, most of the clathrin is localized to large patches that display little lateral mobility. The functional role of these regions is not clear,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00c86b9998dd344804d1f8269f2898d7
https://doi.org/10.1074/jbc.m511370200
https://doi.org/10.1074/jbc.m511370200
Publikováno v:
Journal of Biological Chemistry. 281:14615-14621
Type I deiodinase is the best characterized member of a small family of selenoenzymes catalyzing the bioactivation and disposal of thyroid hormone. This enzyme is an integral membrane protein composed of two 27-kDa subunits that assemble into a funct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71ab80a0a25f8ed3ee08262e28ab43b9
https://doi.org/10.1074/jbc.m600783200
https://doi.org/10.1074/jbc.m600783200
Autor:
Amanda A. Tutto, Jacob P. S. Johnson, Zhongming Mou, Jack L. Leonard, Michelle Yang, Kate L. Liebmann, Ryan T. Leonard, Karl Simin, Scot A. Wolfe, Jilin Liu, Prashant Kumar, Deborah M. Leonard, Jaime J. Rivera
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0184458 (2017)
[This corrects the article DOI: 10.1371/journal.pone.0181724.].
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a243fdfa01f054a3620e17bbb4373ba
https://doi.org/10.1371/journal.pone.0184458
https://doi.org/10.1371/journal.pone.0184458