Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Deborah L. W. Chong"'
Autor:
Deborah L. W. Chong, Carine Rebeyrol, Ricardo J. José, Andrew E. Williams, Jeremy S. Brown, Chris J. Scotton, Joanna C. Porter
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Neutrophil migration into the airways is an important process to fight infection and is mediated by cell adhesion molecules. The intercellular adhesion molecules, ICAM-1 (CD54) and ICAM-2 (CD102) are known ligands for the neutrophil integrins, lympho
Externí odkaz:
https://doaj.org/article/6a41350cf4c24cef84773ab0c32df0da
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
In 2019 10 million people developed symptomatic tuberculosis (TB) disease and 1.2 million died. In active TB the inflammatory response causes tissue destruction, which leads to both acute morbidity and mortality. Tissue destruction in TB is driven by
Externí odkaz:
https://doaj.org/article/9d2a4ceb833240fd8845101542c2c9e0
Autor:
Akif A. Khawaja, Deborah L. W. Chong, Jagdeep Sahota, Theresia A. Mikolasch, Charis Pericleous, Vera M. Ripoll, Helen L. Booth, Saif Khan, Manuel Rodriguez-Justo, Ian P. Giles, Joanna C. Porter
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Neutrophilic inflammation correlates with mortality in fibrotic interstitial lung disease (ILD) particularly in the most severe form, idiopathic pulmonary fibrosis (IPF), although the underlying mechanisms remain unclear. Neutrophil function is modul
Externí odkaz:
https://doaj.org/article/5210d6d6f7624959a7d494252cd021f5
Autor:
Sara Brilha, Deborah L. W. Chong, Akif A. Khawaja, Catherine W. M. Ong, Naomi J. Guppy, Joanna C. Porter, Jon S. Friedland
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Pulmonary tuberculosis (TB) is caused by inhalation of Mycobacterium tuberculosis, which damages the bronchial epithelial barrier to establish local infection. Matrix metalloproteinase-1 plays a crucial role in the immunopathology of TB, causing brea
Externí odkaz:
https://doaj.org/article/17eacfaa2a7a49dfab8a9c7f006aa095
Autor:
Ashley M Whittington, Frances S Turner, Friedrich Baark, Sam Templeman, Daniela E Kirwan, Candice Roufosse, Nitya Krishnan, Brian D Robertson, Deborah L W Chong, Joanna C Porter, Robert H Gilman, Jon S Friedland
Publikováno v:
PLoS Pathogens, Vol 19, Iss 7, p e1011495 (2023)
Mycobacterium tuberculosis (M.tb) infection causes marked tissue inflammation leading to lung destruction and morbidity. The inflammatory extracellular microenvironment is acidic, however the effect of this acidosis on the immune response to M.tb is
Externí odkaz:
https://doaj.org/article/f0eefa760a3340aa8ca68867ab1b8d6d
Autor:
Jama Dalel, Jia Wei Teo, Seng K. Ung, Alisha McPherson, S. Lucas Black, Deborah L. W. Chong, Peter Hayes, Catherine N. Kibirige, The IAVI Protocol C. Investiga list, Matt A. Price, Sarah Joseph, Faith Osier, Nesrina Imami, Jill Gilmour, Julia Makinde
Publikováno v:
SSRN Electronic Journal.
Autor:
Yihan Li, Jiten Manji, Daniel M. Altmann, Rosemary J. Boyton, Amy Cutler, S. Lucas Black, Catherine J. Reynolds, Zoe Webster, Deborah L. W. Chong
Publikováno v:
The Journal of Immunology Author Choice
IFN-γ is a key cytokine of innate and adaptive immunity. It is important to understand temporal changes in IFN-γ production and how these changes relate to the role of IFN-γ in diverse models of infectious and autoimmune disease, making the abilit
Autor:
Joanna C. Porter, H.S. Garthwaite, T.A. Mikolasch, Melissa Heightman, Helen Booth, Deborah L. W. Chong, J. Sahota, E.K. Dennery
Publikováno v:
A62. LUNG FIBROSIS: INSIGHTS FROM THE BENCH.
Autor:
Myriam Labelle, S Trinder, S. Hughes, Manuel Rodriguez-Justo, Deborah L. W. Chong, Alan M. Holmes, Chris J. Scotton, Joanna C. Porter
Publikováno v:
Journal of Tissue Engineering and Regenerative Medicine
Platelets are a recognised potent source of transforming growth factor‐β1 (TGFβ1), a cytokine known to promote wound healing and regeneration by stimulating dermal fibroblast proliferation and extracellular matrix deposition. Platelet lysate has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb58964180a3237d81c2f2aec0e6cf76
https://openaccess.sgul.ac.uk/id/eprint/111952/1/term.3022.pdf
https://openaccess.sgul.ac.uk/id/eprint/111952/1/term.3022.pdf
Autor:
Deborah L. W. Chong, J. Sahota, Saif Khan, Akif A. Khawaja, Vera M. Ripoll, Ian Giles, Manuel Rodriguez-Justo, Charis Pericleous, Helen Booth, Joanna C. Porter
Neutrophilic inflammation correlates with mortality in fibrotic interstitial lung disease (ILD) however, the underlying mechanisms remain unclear. We aimed to determine whether aberrant neutrophil activation is a feature of ILD and the relative role
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2d3c3c4862599dd1e51cfc09adc8017
https://doi.org/10.1101/2020.01.03.894196
https://doi.org/10.1101/2020.01.03.894196