Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Deborah L. Holliday"'
Autor:
Carlos López-Otín, Xose S. Puente, Fred C.G.J. Sweep, Paul N. Span, J. Louise Jones, Deborah L. Holliday, Dylan R. Edwards, Simon Pilgrim, Caroline J. Pennington, Cecilia Garabaya, Alicia R. Folgueras, Antonio Fueyo, Ana Gutiérrez-Fernández
Supplementary Figure 1 from Matrix Metalloproteinase-8 Functions as a Metastasis Suppressor through Modulation of Tumor Cell Adhesion and Invasion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4e711a6632d64015dc9850ddc2f0e13
https://doi.org/10.1158/0008-5472.22374980.v1
https://doi.org/10.1158/0008-5472.22374980.v1
Autor:
Carlos López-Otín, Xose S. Puente, Fred C.G.J. Sweep, Paul N. Span, J. Louise Jones, Deborah L. Holliday, Dylan R. Edwards, Simon Pilgrim, Caroline J. Pennington, Cecilia Garabaya, Alicia R. Folgueras, Antonio Fueyo, Ana Gutiérrez-Fernández
Collagenase-2 (matrix metalloproteinase-8, MMP-8) is an MMP mainly produced by neutrophils and associated with many inflammatory conditions. We have previously described that MMP-8 plays a protective role in cancer through its ability to regulate the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c52502d9be0b2e1d17402c309bcb9012
https://doi.org/10.1158/0008-5472.c.6497663
https://doi.org/10.1158/0008-5472.c.6497663
Autor:
Grace C Roberts, Paul G Morris, Marcus A Moss, Sarah L Maltby, Chelsea A Palmer, Claire E Nash, Emily Smart, Deborah L Holliday, Valerie Speirs
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0157004 (2016)
BACKGROUND:3D cell cultures are emerging as more physiologically meaningful alternatives to monolayer cultures for many biological applications. They are attractive because they more closely mimic in vivo morphology, especially when co-cultured with
Externí odkaz:
https://doaj.org/article/fcf8b86f83a147cc8f4ce000a15fbabf
Publikováno v:
Prenatal diagnosis. 42(2)
The adoption of massively parallel short-read DNA sequencing methods has greatly expanded the scope and availability of genetic testing for inherited diseases. Indeed, the power of these methods has encouraged the integration of whole genome sequenci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1e465848302086cc01111ba4cb28b5a
https://pubmed.ncbi.nlm.nih.gov/35014072
https://pubmed.ncbi.nlm.nih.gov/35014072
Autor:
Georgia Mavria, Darren C. Tomlinson, Valerie Speirs, Fedor Berditchevski, Darren Treanor, Euan W. Baxter, Andrew M. Hanby, Vera Novitskaya, Claire Nash, Deborah L. Holliday
Publikováno v:
Oncotarget
Multicellular 3-dimensional (3D) in vitro models of normal human breast tissue to study cancer initiation are required. We present a model incorporating three of the major functional cell types of breast, detail the phenotype and document our breast
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::177691f91299d7a848a9d4d1a323f467
http://europepmc.org/articles/PMC4537045
http://europepmc.org/articles/PMC4537045
Autor:
Ewan E. Morrison, Mohamed Kamal, Deborah L. Holliday, Sandra M. Bell, Carmel Toomes, Valerie Speirs
The CUB and sushi multiple domains 1 (CSMD1) gene maps to chromosome 8p23, a region deleted in many cancers. Loss of CSMD1 expression is associated with poor prognosis in breast cancer suggesting that it acts as a tumour suppressor in this cancer. Ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7d8649e29d0adabf4825c8e32bcb875
Autor:
Helene Thygesen, Xiaomei Lu, Caroline A. Green, James L. Thorne, Mark A. Hull, Andrew M. Hanby, Ruth Drury, Alexandre Zougman, Deborah L. Holliday, Thomas A. Hughes, Eldo T. Verghese, Valerie Speirs, Claire Nash
Publikováno v:
The Journal of Pathology. 231:388-399
Carcinoma-associated fibroblasts (CAFs) influence the behaviour of cancer cells but the roles of microRNAs in this interaction are unknown. We report microRNAs that are differentially expressed between breast normal fibroblasts and CAFs of oestrogen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::689790cd795308353b86ac435a5988ac
https://doi.org/10.1002/path.4248
https://doi.org/10.1002/path.4248
Autor:
Reza Vaziri, S. Vallath, Ian R. Hart, S. Dreger, Harriet Nitch-Smith, J. Louise Jones, Claude Chelala, Adam R. Brentnall, Deborah L Holliday, Jane Hayward, Michael D. Allen, Robert Carpenter, Michael Green, Rosemary A. Walker
Publikováno v:
The Journal of Pathology. 223:646-658
Integrin α9β1 is a receptor for ECM proteins, including Tenascin-C and the EDA domain of fibronectin, and has been shown to transduce TGFβ signalling. This study has examined the expression pattern of α9β1 in 141 frozen breast carcinoma samples
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e637265886f511d00cc452b66a79f6f5
https://doi.org/10.1002/path.2833
https://doi.org/10.1002/path.2833
Autor:
Deborah L Holliday, Antonio Fueyo, Caroline J. Pennington, Ana Gutiérrez-Fernández, Alicia R. Folgueras, Paul N. Span, Carlos López-Otín, J. Louise Jones, Fred C.G.J. Sweep, Dylan R. Edwards, Cecilia Garabaya, Simon Pilgrim, Xose S. Puente
Publikováno v:
Cancer Research
Cancer Research, 68, 2755-63
Cancer Research; Vol 68
Cancer Research, 68, 8, pp. 2755-63
Cancer Research, 68, 2755-63
Cancer Research; Vol 68
Cancer Research, 68, 8, pp. 2755-63
Contains fulltext : 69166.pdf (Publisher’s version ) (Closed access) Collagenase-2 (matrix metalloproteinase-8, MMP-8) is an MMP mainly produced by neutrophils and associated with many inflammatory conditions. We have previously described that MMP-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0217cc4976c702ada812ed69eeba7e70
Autor:
Grace C, Roberts, Paul G, Morris, Marcus A, Moss, Sarah L, Maltby, Chelsea A, Palmer, Claire E, Nash, Emily, Smart, Deborah L, Holliday, Valerie, Speirs
Publikováno v:
PLoS ONE
Background 3D cell cultures are emerging as more physiologically meaningful alternatives to monolayer cultures for many biological applications. They are attractive because they more closely mimic in vivo morphology, especially when co-cultured with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::20fff12096c8b686667782eb55267ced
https://pubmed.ncbi.nlm.nih.gov/27300768
https://pubmed.ncbi.nlm.nih.gov/27300768