Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Deborah L. Donohoe"'
Autor:
Deborah L. Donohoe, Katherine Dennert, Rajeev Kumar, Bonnie P. Freudinger, Alexander J. Sherman
Publikováno v:
3D Printing in Medicine, Vol 7, Iss 1, Pp 1-9 (2021)
Abstract Background The ability of 3D printing using plastics and resins that are magnetic resonance imaging (MRI) compatible provides opportunities to tailor design features to specific imaging needs. In this study an MRI compatible cradle was desig
Externí odkaz:
https://doaj.org/article/58a9ba5bc2774440bf7b4c2bb3109e06
Autor:
Katherine Fredrich, Jennifer L. Liedel, Deborah L. Donohoe, David M. Gourlay, Nathan P. Heinzerling
Publikováno v:
European Journal of Pediatric Surgery. 26:260-266
Background Breast milk has a heterogeneous composition that differs between mothers and changes throughout the first weeks after birth. The proinflammatory cytokine IL-23 has a highly variable expression in human breast milk. We hypothesize that IL-2
Autor:
Melinda R. Dwinell, Shaoying Chen, Shur Jen Wang, Rajasree Sreedharan, Scott K. Van Why, Deborah L. Donohoe, David P. Basile, Brian D. Shames
Publikováno v:
Kidney international
Brown Norway rats (BN, BN/NHsdMcwi) are profoundly resistant to developing acute kidney injury (AKI) following ischemia reperfusion. To help define the genetic basis for this resistance, we used consomic rats, in which individual chromosomes from BN
Autor:
Jennifer L. Liedel, Scott R. Welak, Deborah L. Donohoe, David M. Gourlay, Kirkwood A. Pritchard, Rebecca M. Rentea, Katherine Fredrich, Keith T. Oldham
Publikováno v:
European Journal of Pediatric Surgery. 23:039-047
Introduction Inflammation in the premature intestine is a key factor that leads to the development of necrotizing enterocolitis (NEC). Activation of nuclear factor kappa B (NF-κB) and subsequent inflammation increases the severity of NEC. The aim of
Autor:
Kimberly R. Pechman, D. P. Bedekar, Kathleen M. Schmainda, Shekar N. Kurpad, Deborah L. Donohoe
Publikováno v:
Magnetic Resonance in Medicine. 68:1266-1272
Frequently, bevacizumab is combined with chemotherapeutics such as irinotecan, motivated by studies showing improved clinical outcomes compared to historical controls. However, no systematic studies have been performed to determine if and how these d
Autor:
David L. Mattson, Hayley Lund, Deborah L. Donohoe, Leilani James, Kimberly R. Spurgeon-Pechman, David P. Basile
Publikováno v:
American Journal of Physiology-Renal Physiology. 293:F269-F278
Recovery of renal function is a well-characterized feature of models of acute renal failure; however, more recent studies have reported a predisposition to chronic renal disease. This study sought to determine the susceptibility to sodium-dependent h
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 289:R1770-R1776
In addition to the long-term renal complications, previous studies suggested that after acute renal failure (ARF), rats manifest an increased pressor response to an overnight infusion of ANG II. The present study tested whether recovery from ARF resu
Publikováno v:
American Journal of Physiology-Renal Physiology. 288:F568-F577
Transforming growth factor (TGF)-β1and a number of TGF-β-responsive genes are transiently enhanced following induction of ischemic acute renal failure (ARF) in the rat. The mRNA and protein expression of TGF-β receptors were analyzed in postischem
Publikováno v:
Kidney International. 65(6):2201-2211
Resistance to ischemic acute renal failure in the Brown Norway rat: A new model to study cytoprotection. Background An in vivo model of intrinsic resistance to ischemia could be invaluable to define how specific pathways to injury or putative protect
Publikováno v:
American Journal of Physiology-Renal Physiology. 284:F338-F348
Ischemic acute renal failure (ARF) results in the permanent loss of peritubular capillaries and predisposes the progression of chronic renal failure. The present study was undertaken to determine whether renal hypoxia, which may represent an importan