Zobrazeno 1 - 10
of 86
pro vyhledávání: '"Deborah L. Baines"'
Publikováno v:
Cells, Vol 12, Iss 7, p 997 (2023)
Primary human bronchial epithelial cultures (HBECs) are used to study airway physiology, disease, and drug development. HBECs often replicate human airway physiology/pathophysiology. Indeed, in the search for cystic fibrosis (CF) transmembrane conduc
Externí odkaz:
https://doaj.org/article/bc4b51a09f7742f7b49148799df05802
Autor:
Jade Bearham, Nina Krutrök, Botilda Lindberg, Maximillian Woodall, Annika Astrand, John D Taylor, Matthew Biggart, Stanislavs Vasiljevs, Robert Tarran, Deborah L Baines
Publikováno v:
PLoS ONE, Vol 16, Iss 7, p e0254248 (2021)
We have modified the periplasmic Escherichia coli glucose/galactose binding protein (GBP) and labelled with environmentally sensitive fluorophores to further explore its potential as a sensor for the evaluation of glucose concentration in airway surf
Externí odkaz:
https://doaj.org/article/6fa398a5f63244c588c16a9063879c43
Publikováno v:
American journal of physiology. Cell physiology. 324(1)
New technologies such as single-cell RNA sequencing (scRNAseq) has enabled identification of the mRNA transcripts expressed by individual cells. This review provides insight from recent scRNAseq studies on the expression of glucose transporters in th
Autor:
Victoria Schroeder, Maximillian Woodall, J. Jacob, James P. Garnett, Robert Tarran, I. Khan, Deborah L. Baines, B. Kenyon, Kameljit K. Kalsi, E. Davis
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology
Electronic nicotine delivery systems, or e-cigarettes, utilize a liquid solution that normally contains propylene glycol (PG) and vegetable glycerin (VG) to generate vapor and act as a carrier for nicotine and flavorings. Evidence indicated these “
Publikováno v:
American Journal of Physiology-Cell Physiology
Airway secretions contain many signaling molecules and peptides/proteins that are not found in airway surface liquid (ASL) generated by normal human bronchial epithelial cells (NHBEs) in vitro. These play a key role in innate defense and mediate comm
Publikováno v:
Frontiers in Pharmacology, Vol 5 (2014)
Diabetic nephropathy is one of the most common causes of renal impairment. Podocytes are specialised cells integral to normal kidney physiology, however in diabetes injury occurs leading to compromised function which is a critical factor in the devel
Externí odkaz:
https://doaj.org/article/46a16fc160444e5bb2943b61a1f469f9
Publikováno v:
Bioscience Reports
Background: In the kidney glucose is freely filtered by the glomerulus and, mainly, reabsorbed by sodium glucose cotransporter 2 (SGLT2) expressed in the early proximal tubule. Human proximal tubule epithelial cells (PTECs) undergo pathological and f
Publikováno v:
Physiology News.
Publikováno v:
The FASEB Journal. 35
Autor:
Patrick T. Harrison, Amy Walker, A. Aldossary, Stephen L. Hart, David J. Sanz, R. Maeshima, M. Woodall, R. McAnulty, D. J. Pearce, I. Guerrini, M. O’Hara-Wright, Deborah L. Baines, Christopher O'Callaghan
Publikováno v:
Journal of Cystic Fibrosis. 20:S281-S282