Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Deborah L Cross"'
Autor:
Henderson Zhu, Irina Chelysheva, Deborah L. Cross, Luke Blackwell, Celina Jin, Malick M. Gibani, Elizabeth Jones, Jennifer Hill, Johannes Trück, Dominic F. Kelly, Christoph J. Blohmke, Andrew J. Pollard, Daniel O’Connor
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 16 (2023)
BACKGROUND Typhoid fever is caused by the Gram-negative bacterium Salmonella enterica serovar Typhi and poses a substantial public health burden worldwide. Vaccines have been developed based on the surface Vi-capsular polysaccharide of S. Typhi; thes
Externí odkaz:
https://doaj.org/article/b81e2d3d809c4b209e52887756c00f03
Autor:
Deborah L. Cross, Marije K. Verheul, Michael D. Leipold, Gerlinde Obermoser, Celina Jin, Elizabeth Jones, Joshua S. Starr, Irina Mohorianu, Christoph J. Blohmke, Holden T. Maecker, Giorgio Napolitani, Jennifer Hill, Andrew J. Pollard
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Vi-polysaccharide conjugate vaccines are efficacious against cases of typhoid fever; however, an absolute correlate of protection is not established. In this study, we investigated the leukocyte response to a Vi-tetanus toxoid conjugate vaccine (Vi-T
Externí odkaz:
https://doaj.org/article/18154f04f8854243816e5256d03d16db
Autor:
Deborah L. Cross, Erik D. Layton, Krystle K.Q. Yu, Malisa T. Smith, Melissa S. Aguilar, Shamin Li, Harriet Mayanja-Kizza, Catherine M. Stein, W. Henry Boom, Thomas R. Hawn, Philip Bradley, Evan Newell, Chetan Seshadri
T cells are required for a protective immune response against the human adapted pathogenMycobacterium tuberculosis(M.tb). We recently described a cohort of Ugandan household contacts of tuberculosis cases that appear to ‘resist’ M.tb infection (R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc149893262e00eea6aa92d769a1cdb4
https://doi.org/10.1101/2022.10.12.511825
https://doi.org/10.1101/2022.10.12.511825
Autor:
Shaikh Shimaz Hashimdeen, David Price, Stephen Man, Kristin Ladell, James E. Redman, Linda Wooldridge, Pierre J. Rizkallah, Reiss Reid, Deborah L Cross, David K. Cole, Bethan Davies, Kelly L. Miners, Anya Lissina, Ilona Can, Paul E. Brown, Sian Llewellyn-Lacey
Publikováno v:
The Journal of Immunology. 207:1009-1017
The human CD8+ T cell clone 6C5 has previously been shown to recognize the tert-butyl-modified Bax161–170 peptide LLSY(3-tBu)FGTPT presented by HLA-A*02:01. This nonnatural epitope was likely created as a by-product of fluorenylmethoxycarbonyl prot
Autor:
Giorgio Napolitani, M K Verheul, Deborah L Cross, Irina Mohorianu, Jennifer Hill, Holden T. Maecker, Celina Jin, Joshua S Starr, Gerlinde Obermoser, Elizabeth Jones, Andrew J. Pollard, Michael D. Leipold, Christoph J. Blohmke
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Frontiers in Immunology
Frontiers in Immunology
Vi-polysaccharide conjugate vaccines are efficacious against cases of typhoid fever; however, an absolute correlate of protection is not established. In this study, we investigated the leukocyte response to a Vi-tetanus toxoid conjugate vaccine (Vi-T
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Frontiers in Immunology
Frontiers in Immunology
Sepsis has a complex pathophysiology in which both excessive and refractory inflammatory responses are hallmark features. Pro-inflammatory cytokine responses during the early stages are responsible for significant endothelial dysfunction, loss of end