Zobrazeno 1 - 10
of 114
pro vyhledávání: '"Deborah L, Galson"'
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Multiple myeloma (MM) is an incapacitating hematological malignancy characterized by accumulation of cancerous plasma cells in the bone marrow (BM) and production of an abnormal monoclonal protein (M-protein). The BM microenvironment has a key role i
Externí odkaz:
https://doaj.org/article/93f18b0737f542da94b3ffea6fb665c9
Publikováno v:
Journal of Bone Oncology, Vol 13, Iss , Pp 62-70 (2018)
Multiple myeloma (MM) is the most frequent cancer to involve the skeleton with patients developing osteolytic bone lesions due to hyperactivation of osteoclasts and suppression of BMSCs differentiation into functional osteoblasts. Although new therap
Externí odkaz:
https://doaj.org/article/370f384d84a040bf9a8e82f8bf0c3ed9
Autor:
Daniela N Petrusca, Denise Toscani, Feng-Ming Wang, Cheolkyu Park, Colin D Crean, Judith L Anderson, Silvia Marino, Khalid S Mohammad, Dan Zhou, Rebecca Silbermann, Quanhong Sun, Noriyoshi Kurihara, Deborah L Galson, Nicola Giuliani, G David Roodman
Publikováno v:
Journal of Hematology & Oncology, Vol 11, Iss 1, Pp 1-14 (2018)
Abstract Background In spite of major advances in treatment, multiple myeloma (MM) is currently an incurable malignancy due to the emergence of drug-resistant clones. We previously showed that MM cells upregulate the transcriptional repressor, growth
Externí odkaz:
https://doaj.org/article/208324c0cf064ed1a922de5482666482
Publikováno v:
JBMR Plus, Vol 3, Iss 3, Pp n/a-n/a (2019)
ABSTRACT Multiple myeloma (MM) bone disease is characterized by the development of osteolytic lesions, which cause severe complications affecting the morbidity, mortality, and treatment of myeloma patients. Myeloma tumors seeded within the bone micro
Externí odkaz:
https://doaj.org/article/0f1fe92918b84f49b8666bfb0a39b2f6
Autor:
Shivendra V. Singh, Prashant N. Kumta, Boeun Lee, Rebecca J. Watters, Kurt R. Weiss, Deborah L. Galson, Juraj Adamik, Carolyn J. Anderson, Joseph D. Latoche, Lea Nyiranshuti, Krishna B. Singh, Su-Hyeong Kim, Eun-Ryeong Hahm, Subrata K. Pore
Consensus binding sequences for transcription factors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afd090210304acc1e6136632d1f1ace2
https://doi.org/10.1158/1535-7163.22521588.v1
https://doi.org/10.1158/1535-7163.22521588.v1
Autor:
Shivendra V. Singh, Prashant N. Kumta, Boeun Lee, Rebecca J. Watters, Kurt R. Weiss, Deborah L. Galson, Juraj Adamik, Carolyn J. Anderson, Joseph D. Latoche, Lea Nyiranshuti, Krishna B. Singh, Su-Hyeong Kim, Eun-Ryeong Hahm, Subrata K. Pore
Expression of runt-related transcription factor 2 (RUNX2) protein in luminal-type breast cancers and normal mammary tissues.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d53e8a3486cb065405199697dea1239
https://doi.org/10.1158/1535-7163.22521597
https://doi.org/10.1158/1535-7163.22521597
Autor:
Shivendra V. Singh, Prashant N. Kumta, Boeun Lee, Rebecca J. Watters, Kurt R. Weiss, Deborah L. Galson, Juraj Adamik, Carolyn J. Anderson, Joseph D. Latoche, Lea Nyiranshuti, Krishna B. Singh, Su-Hyeong Kim, Eun-Ryeong Hahm, Subrata K. Pore
Bone is the most preferred site for colonization of metastatic breast cancer cells for each subtype of the disease. The standard of therapeutic care for breast cancer patients with bone metastasis includes bisphosphonates (e.g., zoledronic acid), whi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afd2a024fd1a914000a0387ee50e9c13
https://doi.org/10.1158/1535-7163.c.6543075.v1
https://doi.org/10.1158/1535-7163.c.6543075.v1
Autor:
Konstantinos Lontos, Juraj Adamik, Anastasia Tsagianni, Deborah L. Galson, John M. Chirgwin, Attaya Suvannasankha
Publikováno v:
Frontiers in Endocrinology, Vol 9 (2018)
Semaphorin 4D (Sema4D; CD100) is a transmembrane homodimer 150-kDa glycoprotein member of the Semaphorin family. Semaphorins were first identified as chemorepellants that guide neural axon growth. Sema4D also possesses immune regulatory activity. Rec
Externí odkaz:
https://doaj.org/article/ef6c97d4b9c94ecaad27511977266da3
Autor:
Juraj Adamik, Rebecca Silbermann, Silvia Marino, Quanhong Sun, Judith L. Anderson, Dan Zhou, Xiang-Qun Xie, G. David Roodman, Deborah L. Galson
Publikováno v:
Frontiers in Endocrinology, Vol 9 (2018)
Multiple myeloma bone disease (MMBD) is characterized by non-healing lytic bone lesions that persist even after a patient has achieved a hematologic remission. We previously reported that p62 (sequestosome-1) in bone marrow stromal cells (BMSC) is cr
Externí odkaz:
https://doaj.org/article/80269853b1004c998e02acf75da8e696
Autor:
David N. Boone, Yuanyuan Chen, Kenneth J. DeHaan, Sheila Pratt, Tobias A. Baker, Steve Evans, Malihe Alikhani, Steffi Oesterreich, Jennifer M. Atkinson, Andrew W. Duncan, Deborah L. Galson, Greg M. Delgoffe, Tullia C. Bruno, Solomon Livshits, Richard D. Boyce, Joseph C. Ayoob
Publikováno v:
J STEM Outreach
The University of Pittsburgh Medical Center Hillman Cancer Center Academy (Hillman Academy) has the primary goal of reaching high school students from underrepresented and disadvantaged backgrounds and guiding them through a cutting-edge research and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa0b1ee826dad0b18fda472b94a26cbd
https://europepmc.org/articles/PMC9997544/
https://europepmc.org/articles/PMC9997544/