Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Deborah K. Hill"'
Autor:
Deborah K. Hill, Andreas Heindl, Konstantinos Zormpas-Petridis, David J. Collins, Leslie R. Euceda, Daniel N. Rodrigues, Siver A. Moestue, Yann Jamin, Dow-Mu Koh, Yinyin Yuan, Tone F. Bathen, Martin O. Leach, Matthew D. Blackledge
Publikováno v:
Frontiers in Oncology, Vol 7 (2017)
Diffusion-weighted magnetic resonance imaging (DWI) enables non-invasive, quantitative staging of prostate cancer via measurement of the apparent diffusion coefficient (ADC) of water within tissues. In cancer, more advanced disease is often character
Externí odkaz:
https://doaj.org/article/8bccd82feb6548fa819ce2cb788c94bc
Autor:
Catharina de Lange Davies, Deborah K. Hill, Jana Kim, Annemieke van Wamel, Stein-Martin Tilrum Fagerland
Publikováno v:
The Prostate
Background:The transgenic adenocarcinoma of the mouse prostate (TRAMP) is a widelyused genetically engineered spontaneous prostate cancer model. However, both thedegree of malignancy and time of cancer onset vary. While most mice display slowlyprogre
Autor:
Gigin Lin, Gabriela Andrejeva, Anne-Christine Wong Te Fong, Deborah K Hill, Matthew R Orton, Harry G Parkes, Dow-Mu Koh, Simon P Robinson, Martin O Leach, Thomas R Eykyn, Yuen-Li Chung
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e92645 (2014)
Autophagy is a highly regulated, energy dependent cellular process where proteins, organelles and cytoplasm are sequestered in autophagosomes and digested to sustain cellular homeostasis. We hypothesized that during autophagy induced in cancer cells
Externí odkaz:
https://doaj.org/article/9175f8dc0853424ca4a36e28c152cc93
Autor:
Pernille Rose Jensen, Jan Henrik Ardenkjær-Larsen, Tone Frost Bathen, Mathilde H. Lerche, Siver Andreas Moestue, Anne Birk Frahm, Trygve Andreassen, Deborah K. Hill, Sotirios Katsikis
Publikováno v:
Talanta: The International Journal of Pure and Applied Analytical Chemistry
Hyperpolarized 13C isotope resolved spectroscopy boosts NMR signal intensity, which improves signal detection and allows metabolic fluxes to be analyzed. Such hyperpolarized flux data may offer new approaches to tissue classification and biomarker id
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::144afa70a92e59bdadac4a203bd56f15
https://hdl.handle.net/11250/2944222
https://hdl.handle.net/11250/2944222
Autor:
Einar Sulheim, Catharina de Lange Davies, Astrid Hyldbakk, Deborah K. Hill, Stein-Martin Tilrum Fagerland, Sigrid Berg, Jana Kim, Sofie Snipstad
Publikováno v:
Ultrasound in Medicine and Biology
Ultrasound (US) in combination with microbubbles (MB) has had promising results in improving delivery of chemotherapeutic agents. However, most studies are done in immunodeficient mice with xenografted tumors. We used two phenotypes of the spontaneou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ecc5c3f488c26d9778ab4d63dfeef60
https://hdl.handle.net/11250/2722213
https://hdl.handle.net/11250/2722213
Publikováno v:
NMR-based Metabolomics ISBN: 9781849736435
Magnetic resonance spectroscopy (MRS) is limited by low signal strength at thermal equilibrium owing to low spin polarisation. NMR spectroscopy and MR spectroscopic imaging are therefore subject to constraints in both spatial and temporal resolution,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5429ea044e8e983ea5879f231af09a16
https://doi.org/10.1039/9781782627937-00280
https://doi.org/10.1039/9781782627937-00280
Autor:
Siver Andreas Moestue, Tone Frost Bathen, Nina-Beate Liabakk, Morten Beck Rye, Marit Otterlei, Caroline Danielsen Søgaard, Deborah K. Hill, Anala Nepal, Siri Bachke, Jana Kim
Publikováno v:
11752-11766
OncoTarget
Oncotarget
OncoTarget
Oncotarget
// Caroline K. Sogaard 1, 7 , Siver A. Moestue 2, 3, 4 , Morten B. Rye 1, 7 , Jana Kim 2, 5 , Anala Nepal 1 , Nina-Beate Liabakk 1 , Siri Bachke 1 , Tone F. Bathen 2, 5 , Marit Otterlei 1, 6, 7 and Deborah K. Hill 2, 5 1 Department of Cancer Research
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db7172037efe67df5f51000bb8f3864a
http://hdl.handle.net/11250/2592602
http://hdl.handle.net/11250/2592602
Autor:
Elisabetta Marangoni, Tone Frost Bathen, Ivan Bièche, Endre Stokke, Deborah K. Hill, Rana Hatem, Leslie R. Euceda, Rania El Botty, Siver Andreas Moestue
Publikováno v:
Journal of Proteome Research
Patients with triple-negative breast cancer (TNBC) are unresponsive to endocrine and anti-HER2 pharmacotherapy, limiting their therapeutic options to chemotherapy. TNBC is frequently associated with abnormalities in the PI3K/AKT/mTOR signaling pathwa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ce70a08ccf11bec705a6dc3d75b26fb
http://hdl.handle.net/11250/2443942
http://hdl.handle.net/11250/2443942
Autor:
Thomas R. Eykyn, Gabriela Andrejeva, Gigin Lin, Helen Troy, M Jafar, Jessica K.R. Boult, Harry G. Parkes, Deborah K. Hill, Y-L Chung, Matthew R. Orton, Simon P. Robinson, John R. Griffiths, D-M. Koh, Ian Judson, Rafal Panek, Martin O. Leach, A-C L F W T Fong
Publikováno v:
British Journal of Cancer
Background: Dichloroacetate (DCA) has been found to have antitumour properties. Methods: We investigated the cellular and metabolic responses to DCA treatment and recovery in human colorectal (HT29, HCT116 WT and HCT116 Bax-ko), prostate carcinoma ce
Autor:
Harold G. Parkes, Deborah K. Hill, Thomas R. Eykyn, Nicolas Tardif, Yann Jamin, Simon P. Robinson, Yuen-Li Chung, Martin O. Leach, Matthew R. Orton
Publikováno v:
NMR in Biomedicine. 26:1321-1325
Pyruvate–lactate exchange is mediated by the enzyme lactate dehydrogenase (LDH) and is central to the altered energy metabolism in cancer cells. The measurement of exchange kinetics using hyperpolarized 13C NMR has provided a biomarker of response