Zobrazeno 1 - 10
of 173
pro vyhledávání: '"Deborah J. Henderson"'
Publikováno v:
Disease Models & Mechanisms, Vol 17, Iss 1 (2024)
Externí odkaz:
https://doaj.org/article/d0393f924a4940e9b28bee03caac9d0e
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2022)
Abnormalities in the arterial valves are some of the commonest congenital malformations, with bicuspid aortic valve (BAV) occurring in as many as 2% of the population. Despite this, most of what we understand about the development of the arterial (se
Externí odkaz:
https://doaj.org/article/2e76ff9795114602b93ae1dcbe707dd2
Autor:
Bill Chaudhry, Ahlam Alqahtani, Lorraine Eley, Louise Coats, Corina Moldovan, Srinivas R. Annavarapu, Deborah J. Henderson
Publikováno v:
Journal of Cardiovascular Development and Disease, Vol 9, Iss 8, p 279 (2022)
Hypoplastic left heart syndrome (HLHS) is a collective term applied to severe congenital cardiac malformations, characterised by a combination of abnormalities mainly affecting the left ventricle, associated valves, and ascending aorta. Although in c
Externí odkaz:
https://doaj.org/article/0332452064554e70b3f7996f4474b8e8
Autor:
Lindsay B. Murphy, Adrian Santos-Ledo, Tamilvendhan Dhanaseelan, Lorraine Eley, David Burns, Deborah J. Henderson, Bill Chaudhry
Publikováno v:
Disease Models & Mechanisms, Vol 14, Iss 7 (2021)
Exercise may ameliorate the eventual heart failure inherent in human aging. In this study, we use zebrafish to understand how aging and exercise affect cardiomyocyte turnover and myocardial remodelling. We show that cardiomyocyte proliferation remain
Externí odkaz:
https://doaj.org/article/c1370ea5856349e19b11db60abc74bb9
Autor:
Kate E. Bailey, Guy A. MacGowan, Simon Tual-Chalot, Lauren Phillips, Timothy J. Mohun, Deborah J. Henderson, Helen M. Arthur, Simon D. Bamforth, Helen M. Phillips
Publikováno v:
JCI Insight, Vol 5, Iss 24 (2020)
Externí odkaz:
https://doaj.org/article/0510ee0db2354312ba898effcad867a9
Autor:
Nigel A. Brown, Deborah J. Henderson
Publikováno v:
Journal of Cardiovascular Development and Disease, Vol 8, Iss 1, p 6 (2021)
Robert (Bob) Henry Anderson was born in Wellington, Shropshire, UK, in 1942 and he completed his medical training in Manchester (UK) in 1966 [...]
Externí odkaz:
https://doaj.org/article/01b8a85a2c914f24a82cb9f902bb1cf9
Publikováno v:
Journal of Cardiovascular Development and Disease, Vol 7, Iss 4, p 38 (2020)
Although in many ways the arterial and atrioventricular valves are similar, both being derived for the most part from endocardial cushions, we now know that the arterial valves and their surrounding structures are uniquely dependent on progenitors fr
Externí odkaz:
https://doaj.org/article/4f7542bca7f8474099fb88c76b676dc8
Autor:
Amy-Leigh Johnson, Jürgen E. Schneider, Timothy J. Mohun, Trevor Williams, Shoumo Bhattacharya, Deborah J. Henderson, Helen M. Phillips, Simon D. Bamforth
Publikováno v:
Journal of Cardiovascular Development and Disease, Vol 7, Iss 3, p 27 (2020)
Congenital cardiovascular malformation is a common birth defect incorporating abnormalities of the outflow tract and aortic arch arteries, and mice deficient in the transcription factor AP-2α (Tcfap2a) present with complex defects affecting these st
Externí odkaz:
https://doaj.org/article/350e5470eb3f4e3491b1366b073b678a
Autor:
Catherine A. Stothard, Silvia Mazzotta, Arjun Vyas, Jurgen E. Schneider, Timothy J. Mohun, Deborah J. Henderson, Helen M. Phillips, Simon D. Bamforth
Publikováno v:
Journal of Cardiovascular Development and Disease, Vol 7, Iss 2, p 20 (2020)
The correct formation of the aortic arch arteries depends on a coordinated and regulated gene expression profile within the tissues of the pharyngeal arches. Perturbation of the gene regulatory networks in these tissues results in congenital heart de
Externí odkaz:
https://doaj.org/article/1d938e6cfc7d4163abd8fc99ebde10dd
Autor:
Gabriel L. Galea, Oleksandr Nychyk, Matteo A. Mole, Dale Moulding, Dawn Savery, Evanthia Nikolopoulou, Deborah J. Henderson, Nicholas D. E. Greene, Andrew J. Copp
Publikováno v:
Disease Models & Mechanisms, Vol 11, Iss 3 (2018)
Human mutations in the planar cell polarity component VANGL2 are associated with the neural tube defect spina bifida. Homozygous Vangl2 mutation in mice prevents initiation of neural tube closure, precluding analysis of its subsequent roles in neurul
Externí odkaz:
https://doaj.org/article/73ca39b5577f4172b3706a326f3894fd