Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Deborah J. Bidanset"'
Autor:
Debra C. Quenelle, Jiri Zemlicka, Zhaohua Yan, Caroll B. Hartline, Earl R. Kern, Deborah J. Bidanset
Publikováno v:
Antimicrobial Agents and Chemotherapy. 48:4745-4753
We reported previously that purine 2-(hydroxymethyl)methylenecyclopropane analogs have good activity against cytomegalovirus infection. A second-generation analog, ( Z )-9-{[2,2-bis-(hydroxymethyl)cyclopropylidene]methyl}guanine (ZSM-I-62, cyclopropa
Publikováno v:
Antiviral Research. 63:61-64
For immunocompromised hosts, human cytomegalovirus (CMV) can be a serious problem. For evaluation of antivirals used to treat CMV retinitis, we have used severe combined immunodeficient mice as hosts for human retinal tissue implanted in the eye and
Autor:
Earl R. Kern, Karen K. Biron, Stephanie L. Williams, Emma A. Harden, Leroy B. Townsend, Deborah J. Bidanset, Mark R. Underwood, John C. Drach, Nicole L. Kushner, Caroll B. Hartline
Publikováno v:
Antimicrobial Agents and Chemotherapy. 47:2186-2192
Herpes simplex virus types 1 and 2 (HSV-1 and HSV-2), varicella-zoster virus (VZV), cytomegalovirus (CMV), Epstein-Barr virus (EBV), human herpesvirus 6 (HHV-6), and human herpesvirus 8 (HHV-8) are responsible for a number of clinical manifestations
Publikováno v:
Antiviral Research. 58:149-157
Epstein–Barr virus (EBV), human herpesvirus type 6 (HHV-6), and human herpesvirus type 8 (HHV-8) comprise a group of lymphotropic herpesviruses which are responsible for a wide range of diseases, including lymphoproliferative disorders and tumors.
Publikováno v:
The Journal of Infectious Diseases. 184:192-195
Because human cytomegalovirus (HCMV) infection and replication are limited to human cells, few animal models can be used to specifically examine the biology of HCMV in vivo. In these studies, fetal human retinal tissue was implanted into the anterior
Publikováno v:
Experimental Neurology. 143:153-161
Computer-enhanced immunohistochemical techniques were applied to quantify the cellular response of rat optic nerve to crush injury to attain the spatial and temporal detail necessary for resolving trends in the process that may be affected by experim
Autor:
Deborah J. Bidanset, Eldon E. Geisert
Publikováno v:
Developmental Brain Research. 75:163-173
During the development of the central nervous system (CNS), adhesive molecules promote the formation of axonal pathways and appropriate neuronal connections by facilitating cellular interactions. In addition to the interactions that bring neurons tog
Regulation of cell substrate adhesion: effects of small galactosaminoglycan-containing proteoglycans
Autor:
Deborah J. Bidanset, Magnus Höök, Richard G. LeBaron, Joanne E. Murphy-Ullrich, Lawrence C. Rosenberg
Publikováno v:
The Journal of Cell Biology
Cell adhesion is a process which is initiated by the attachment of cells to specific sites in adhesive matrix proteins via cell surface receptors of the integrin family. This is followed by a reorganization of cytoskeletal elements which results in c
Autor:
Magnus Höök, Lawrence C. Rosenberg, Clyde Guidry, Haing U. Choi, Rupert Timpl, Deborah J. Bidanset
Publikováno v:
Journal of Biological Chemistry. 267:5250-5256
We have examined the interactions between the small dermatan sulfate proteoglycan decorin and collagen types I-VI using solid phase binding assays. The results of these studies showed that 125I-decorin bound most efficiently to collagen type VI in a
Publikováno v:
Brain Research. 571:165-168
A novel CNS specific keratan sulfate proteoglycan is identified by a monoclonal antibody (mAb) TED15. The antibody recognizes a carbohydrate epitope that is removed from the core protein following keratanase digestion. The relative molecular weight o