Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Deborah J, Wessels"'
Autor:
Deborah J. Wessels, Claude Pujol, Nikash Pradhan, Daniel F. Lusche, Luis Gonzalez, Sydney E. Kelly, Elizabeth M. Martin, Edward R. Voss, Yang-Nim Park, Michael Dailey, Sonia L. Sugg, Sneha Phadke, Amani Bashir, David R. Soll
Publikováno v:
Cell Adhesion & Migration, Vol 15, Iss 1, Pp 224-248 (2021)
We developed a computer-assisted platform using laser scanning confocal microscopy to 3D reconstruct in real-time interactions between metastatic breast cancer cells and human umbilical vein endothelial cells (HUVECs). We demonstrate that MB-231 canc
Externí odkaz:
https://doaj.org/article/7991f97a6dae480db99bc4ec05492b00
Autor:
Daniel F Lusche, Deborah J Wessels, Ryan J Reis, Cristopher C Forrest, Alexis R Thumann, David R Soll
Publikováno v:
PLoS ONE, Vol 16, Iss 4, p e0250175 (2021)
CD44 is a transmembrane glycoprotein that binds to hyaluronic acid, plays roles in a number of cellular processes and is expressed in a variety of cell types. It is up-regulated in stem cells and cancer. Anti-CD44 monoclonal antibodies affect cell mo
Externí odkaz:
https://doaj.org/article/d6a9d756c5e449879b9a3043bd9cd808
Publikováno v:
mSphere, Vol 5, Iss 5 (2020)
ABSTRACT Candida albicans, a pervasive opportunistic pathogen, undergoes a unique phenotypic transition from a “white” phenotype to an “opaque” phenotype. The switch to opaque impacts gene expression, cell morphology, wall structure, metaboli
Externí odkaz:
https://doaj.org/article/c6f5c95f34384faf8f16920846455add
Autor:
Deborah J Wessels, Nikash Pradhan, Yang-Nim Park, Megan A Klepitsch, Daniel F Lusche, Karla J Daniels, Kayla D Conway, Edward R Voss, Suchaeta V Hegde, Thomas P Conway, David R Soll
Publikováno v:
PLoS ONE, Vol 14, Iss 6, p e0218854 (2019)
Tumorigenic cells undergo cell aggregation and aggregate coalescence in a 3D Matrigel environment. Here, we expanded this 3D platform to assess the interactions of normal human dermal fibroblasts (NHDFs) and human primary mammary fibroblasts (HPMFs)
Externí odkaz:
https://doaj.org/article/09bea94a3ce04961ab0abb6fe31c2a55
Autor:
Daniel F, Lusche, Emma C, Buchele, Kanoe B, Russell, Benjamin A, Soll, Michele I, Vitolo, Michael R, Klemme, Deborah J, Wessels, David R, Soll
Publikováno v:
Oncotarget
One possible approach to normalize mutant cells that are metastatic and tumorigenic, is to upregulate a functionally similar homolog of the mutated gene. Here we have explored this hypothesis by generating an overexpressor of TPTE2 (TPIP), a homolog
Autor:
Deborah J, Wessels, Daniel F, Lusche, Spencer, Kuhl, Amanda, Scherer, Edward, Voss, David R, Soll
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1365
This chapter describes 2D quantitative methods for motion analysis as well as 3D motion analysis and reconstruction methods. Emphasis is placed on the analysis of dynamic cell shape changes that occur through extension and retraction of force generat
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 571
For decades, Dictyostelium discoideum has been an efficacious and attractive model system for the study of cell motility, primarily because cells become highly motile during the transition from growth phase to aggregation competence and because the h