Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Deborah Hyink"'
Autor:
Satu Kuure, Cristina Cebrian, Quentin Machingo, Benson C Lu, Xuan Chi, Deborah Hyink, Vivette D'Agati, Christine Gurniak, Walter Witke, Frank Costantini
Publikováno v:
PLoS Genetics, Vol 6, Iss 10, p e1001176 (2010)
The actin depolymerizing factors (ADFs) play important roles in several cellular processes that require cytoskeletal rearrangements, such as cell migration, but little is known about the in vivo functions of ADFs in developmental events like branchin
Externí odkaz:
https://doaj.org/article/86dee68d369d49f882836a7dbd9dd8e6
Autor:
Odyssé Michos, Cristina Cebrian, Deborah Hyink, Uta Grieshammer, Linda Williams, Vivette D'Agati, Jonathan D Licht, Gail R Martin, Frank Costantini
Publikováno v:
PLoS Genetics, Vol 6, Iss 1, p e1000809 (2010)
GDNF signaling through the Ret receptor tyrosine kinase (RTK) is required for ureteric bud (UB) branching morphogenesis during kidney development in mice and humans. Furthermore, many other mutant genes that cause renal agenesis exert their effects v
Externí odkaz:
https://doaj.org/article/0570a987a25d461193ef088a4b034c59
Autor:
John Cijiang He, Bhaskar C. Das, Gokul C. Das, Andrew Wang, Xuan Wang, Kyung Lee, Weijie Yuan, Weijia Zhang, Zhengzhe Li, Paul E. Klotman, Ruijie Liu, Deborah Hyink
Publikováno v:
Am J Physiol Renal Physiol
Human immunodeficiency virus (HIV) infection of kidney cells can lead to HIV-associated nephropathy (HIVAN) and aggravate the progression of other chronic kidney diseases. Thus, a better understanding of the mechanisms of HIV-induced kidney cell inju
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea825f125705d492ffd223ee103858ca
https://pubmed.ncbi.nlm.nih.gov/32657157
https://pubmed.ncbi.nlm.nih.gov/32657157
Autor:
Esther A. Weygant, Hiroyuki Matsumoto, Deborah Hyink, Tomoko Obara, Daiki Kitamura, Tomomi Matsukura, Shosaku Kashiwada, Chisako Inaba, Ralf Janknecht
Publikováno v:
Physiological Reports
Physiological Reports, Vol 7, Iss 14, Pp n/a-n/a (2019)
Physiological Reports, Vol 7, Iss 14, Pp n/a-n/a (2019)
Treatment modalities for kidney disease caused by long‐term exposure to heavy metals, such as cadmium (Cd), are limited. Often, chronic, long‐term environmental exposure to heavy metal is not recognized in the early stages; therefore, chelation t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05ae256c3cca9dcabc9c213f27022492
http://europepmc.org/articles/PMC6642321
http://europepmc.org/articles/PMC6642321
Autor:
Benjamin Dao, Bishoy Elbebabawy, Ibrahim Sayid, Jagdesh Kandala, Harish Raj Seetha Rammohan, Daniel Katz, Paul Jenkins, Anne Gadomski, Deborah Hyink, Paul Klotman, Randolph Hutter
Publikováno v:
Circulation. 138
Introduction: Our group has shown the Wnt-pathway to be a key regulator of SMC function and to be expressed in human coronary atheroma. Dickkopf-related protein 1 (DKK-1) is a member of the Wingless (Wnt) signaling pathway molecules and has recently
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::37afe1843b64debefa633dfa96bef025
https://doi.org/10.1161/circ.138.suppl_1.17353
https://doi.org/10.1161/circ.138.suppl_1.17353
Autor:
Huilin Li, Deborah Hyink, Weijia Zhang, John Cijiang He, Paul E. Klotman, Mohamad Sidani, Gokul C. Das, Gengru Jiang, Fang Zhong, Weijing Cai, Zhengzhe Li, Yifan Xie, Jae Choi, Kyung Lee
Publikováno v:
Kidney international. 94(6)
Mounting evidence suggests that epigenetic modification is important in kidney disease pathogenesis. To determine whether epigenetic regulation is involved in HIV-induced kidney injury, we performed genome-wide methylation profiling and transcriptomi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b64a8bf40a6a4f8a463e02048e7b311f
https://pubmed.ncbi.nlm.nih.gov/30366682
https://pubmed.ncbi.nlm.nih.gov/30366682
Autor:
Kanjit Leungsuwan, Abdullah Shahid, Paul E. Klotman, Randolph Hutter, Paul Jenkins, Melissa Scribani, Harish Raj Seetha Rammohan, Daniel H. Katz, Jennifer Victory, Saeeda Fatima, Deborah Hyink
Publikováno v:
Journal of the American College of Cardiology. 73:958
Aortic Stenosis (AS) may result in maladaptive left ventricular (LV) remodeling. Wingless (Wnt) modulators have been shown to impact LV ejection fraction (LVEF) in patients with AS. In this study we investigated the additional role of podocan and its
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cdcad740d54725306744d67dae70bdd3
https://doi.org/10.1016/s0735-1097(19)31565-7
https://doi.org/10.1016/s0735-1097(19)31565-7
Autor:
Deborah Hyink, Jennifer Victory, Paul E. Klotman, Benjamin Dao, Jagdesh Kandala, Bishesh Shrestha, Paul M. Jenkins, Kanramon Watthanasuntorn, Charat Thongprayoon, Randolph Hutter, Melissa Scribani
Publikováno v:
Journal of the American College of Cardiology. 73:159
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::13c4975911027f6c5efb008b559de27b
https://doi.org/10.1016/s0735-1097(19)30767-3
https://doi.org/10.1016/s0735-1097(19)30767-3
Autor:
Patricia D. Wilson, Richard Sandford, Ruth L. Case, Xiaohong Li, Catherine A. Boucher, Angela Wandinger-Ness, Heather H. Ward, Christopher J. Ward, Katie S. Thurston, Tamara Roitbak, Andrew Needham, Deborah Hyink, Seema Qamar, Samantha Powell, Elsa Romero
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1812:1225-1238
Autosomal dominant polycystic kidney disease (ADPKD) is caused by mutation of PKD1 and PKD2 that encode polycystin-1 and polycystin-2. Polycystin-1 is tyrosine phosphorylated and modulates multiple signaling pathways including AP-1, and the identity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6d2c42adb69d1fecffc3a3ad3e4332c
https://doi.org/10.1016/j.bbadis.2010.11.006
https://doi.org/10.1016/j.bbadis.2010.11.006
Publikováno v:
Developmental Biology. 356(2):475-485
Angiogenesis is a fundamental step in several important physiological events and pathological conditions including embryonic development, wound repair, tumor growth and metastasis. PRKX was identified as a novel type-I cAMP-dependent protein kinase g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a7acc12c8ed5efecd9ea61005329e95