Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Deborah E. Williard"'
Autor:
Deborah E. Williard, Shawn D. Harmon, Terry L. Kaduce, Meredith Preuss, Steven A. Moore, Michael E.C. Robbins, Arthur A. Spector
Publikováno v:
Journal of Lipid Research, Vol 42, Iss 9, Pp 1368-1376 (2001)
DHA, the main n-3 PUFA in the brain, is synthesized from n-3 PUFA precursors by astrocytes. To assess the potential of this process to supply DHA for the brain, we investigated whether the synthesis in astrocytes is dependent on DHA availability. Rat
Externí odkaz:
https://doaj.org/article/a7768768bf794ce39a78e33a78f75c00
Autor:
Deborah E. Williard, Joseph O. Nwankwo, Terry L. Kaduce, Shawn D. Harmon, Mira Irons, Hugo W. Moser, Gerald V. Raymond, Arthur A. Spector
Publikováno v:
Journal of Lipid Research, Vol 42, Iss 4, Pp 501-508 (2001)
Polyunsaturated fatty acid (PUFA) utilization was investigated in skin fibroblasts cultured from a female patient with an inherited abnormality in lipid metabolism. These deficient human skin fibroblasts (DF) converted 85–95% less [1-14C]linoleic a
Externí odkaz:
https://doaj.org/article/098e851cd49b4f2e816301dcf16873e2
Publikováno v:
Journal of Lipid Research, Vol 39, Iss 5, Pp 978-986 (1998)
Human skin fibroblasts can convert arachidonic acid to 14- and 16-carbon polyunsaturated fatty acid products by peroxisomal β-oxidation. The purpose of this study was to determine whether similar products are formed from eicosapentaenoic acid (EPA)
Externí odkaz:
https://doaj.org/article/975caa526d034b8e90cc2b665dea4598
Publikováno v:
Journal of Visualized Experiments.
Photobioreactors are illuminated cultivation systems for experiments on phototrophic microorganisms. These systems provide a sterile environment for microalgal cultivation with temperature, pH, and gas composition and flow rate control. At bench-scal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f60a38a518c00a6e78fda986e879cb4
https://doi.org/10.3791/60566
https://doi.org/10.3791/60566
Autor:
Zuobiao Yuan, Erik Twait, Isaac Samuel, Duraisamy Kempuraj, David K. Meyerholz, Deborah E. Williard
Publikováno v:
Pancreatology. 10:536-544
Suitable experimental models of gallstone pancreatitis with systemic inflammation and mortality are limited. We developed a novel murine model of duct-ligation-induced acute pancreatitis associated with multiorgan dysfunction and severe mortality.Lap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a1716e6718ce4f33b09fb27f4f22be6
https://doi.org/10.1159/000320776
https://doi.org/10.1159/000320776
Publikováno v:
The American Journal of Surgery. 200:283-290
Background Mitogen-activated protein (MAP) kinases and nuclear factor kappa B (NF-κB) are implicated in early stages of acute pancreatitis pathogenesis. We investigated the relationship between the p38 MAP kinase and NF-κB in isolated acinar cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95ab578b8a6b59fec32d3ac4349c0215
https://doi.org/10.1016/j.amjsurg.2009.12.004
https://doi.org/10.1016/j.amjsurg.2009.12.004
Publikováno v:
The American Journal of Surgery. 196:675-682
Background Acute lung injury is a major determinant of outcomes in acute pancreatitis. We evaluated acute lung injury and stress kinase activation in ligation-induced acute pancreatitis in mice. Methods Mice with duct ligation or sham operation were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc5a16afa7725dbf18a566d40283d44c
https://doi.org/10.1016/j.amjsurg.2008.07.009
https://doi.org/10.1016/j.amjsurg.2008.07.009
Autor:
Michael E.C. Robbins, Deborah E. Williard, Terry L. Kaduce, Meredith Preuss, Shawn D. Harmon, Arthur A. Spector, Steven A. Moore
Publikováno v:
Journal of Lipid Research, Vol 42, Iss 9, Pp 1368-1376 (2001)
DHA, the main n-3 PUFA in the brain, is synthesized from n-3 PUFA precursors by astrocytes. To assess the potential of this process to supply DHA for the brain, we investigated whether the synthesis in astrocytes is dependent on DHA availability. Rat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2fc82161e8a30bc02bf6b502b563969
http://www.sciencedirect.com/science/article/pii/S0022227520302686
http://www.sciencedirect.com/science/article/pii/S0022227520302686
Autor:
Hugo W. Moser, Mira Irons, Joseph O. Nwankwo, Gerald V. Raymond, Shawn D. Harmon, Arthur A. Spector, Deborah E. Williard, Terry L. Kaduce
Publikováno v:
Journal of Lipid Research, Vol 42, Iss 4, Pp 501-508 (2001)
Polyunsaturated fatty acid (PUFA) utilization was investigated in skin fibroblasts cultured from a female patient with an inherited abnormality in lipid metabolism. These deficient human skin fibroblasts (DF) converted 85–95% less [1-14C]linoleic a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ff5cc1871f5fc7947d1bdd3e2092acf
https://doi.org/10.1016/s0022-2275(20)31158-5
https://doi.org/10.1016/s0022-2275(20)31158-5
Autor:
Deborah E. Williard, Zuobiao Yuan, Isaac Samuel, David K. Meyerholz, Erik Twait, Duraisamy Kempuraj
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e56866 (2013)
PLoS ONE
PLoS ONE
Background Acute pancreatitis is potentially fatal but treatment options are limited as disease pathogenesis is poorly understood. IL-33, a novel IL-1 cytokine family member, plays a role in various inflammatory conditions but its role in acute pancr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59cb926189fe754bfcb6b2705d7b5931
http://europepmc.org/articles/PMC3572073?pdf=render
http://europepmc.org/articles/PMC3572073?pdf=render