Zobrazeno 1 - 10
of 204
pro vyhledávání: '"Deborah E. Leckband"'
Autor:
Noboru Ishiyama, Ritu Sarpal, Megan N. Wood, Samantha K. Barrick, Tadateru Nishikawa, Hanako Hayashi, Anna B. Kobb, Annette S. Flozak, Alex Yemelyanov, Rodrigo Fernandez-Gonzalez, Shigenobu Yonemura, Deborah E. Leckband, Cara J. Gottardi, Ulrich Tepass, Mitsuhiko Ikura
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
Cell-cell adhesion mediated by catenin-cadherin complexes plays a critical role in translating the mechanical forces into physiological responses. Here the authors define a mechanism of force-dependent cadherin-actin linkage dynamically regulated thr
Externí odkaz:
https://doaj.org/article/811fe916ab7f4aa8a28b241ddb5f61db
Autor:
Floor Twiss, Quint Le Duc, Suzanne Van Der Horst, Hamid Tabdili, Gerard Van Der Krogt, Ning Wang, Holger Rehmann, Stephan Huveneers, Deborah E. Leckband, Johan De Rooij
Publikováno v:
Biology Open, Vol 1, Iss 11, Pp 1128-1140 (2012)
Summary Proper regulation of the formation and stabilization of epithelial cell–cell adhesion is crucial in embryonic morphogenesis and tissue repair processes. Defects in this process lead to organ malformation and defective epithelial barrier fun
Externí odkaz:
https://doaj.org/article/475896539af044ddabe3c8bb4d38de38
Publikováno v:
eLife, Vol 9 (2020)
We demonstrate a combined experimental and computational approach for the quantitative characterization of lateral interactions between membrane-associated proteins. In particular, weak, lateral (cis) interactions between E-cadherin extracellular dom
Externí odkaz:
https://doaj.org/article/5bb1ac7860544a73ac2e02b89448891b
Publikováno v:
Journal of Colloid and Interface Science. 606:298-306
The molecular surface properties of zwitterionic polymer coatings are central to their ultra-low fouling properties and effectiveness as steric stabilizers in concentrated salt solutions. Here, Surface Force Apparatus measurements quantified the mole
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0c3e9eefdd64cb9313af148e3fcb2f7
https://doi.org/10.1016/j.jcis.2021.08.004
https://doi.org/10.1016/j.jcis.2021.08.004
Autor:
Whitney E. Sinclair, Ashtamurthy S. Pawate, Ty’Nya A. Larry, Jeremy M. Schieferstein, Joseph J. Whittenberg, Deborah E. Leckband, Paul J. A. Kenis
Publikováno v:
Microfluidics and Nanofluidics. 27
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::880091c271890c3f8abc9607bd60e303
https://doi.org/10.1007/s10404-022-02619-y
https://doi.org/10.1007/s10404-022-02619-y
Publikováno v:
Biomacromolecules. 22:4470-4478
The solubility transition at the lower critical solution temperature (LCST, 32 °C) of poly(N-isopropylacrylamide) (PNIPAM) is widely used as a thermal switch to rapidly and reversibly capture and release proteins and cells. It is generally assumed t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4363d92f6d887d2aafa9f87b9da419cb
https://doi.org/10.1021/acs.biomac.1c00417
https://doi.org/10.1021/acs.biomac.1c00417
Autor:
Li Wang, Priyanka Gajwani, Pallavi Chaturvedi, Zhigang Hong, Zijing Ye, Gregory J. Schwarz, Nicole M. Pohl-Avila, Anne-Marie Ray, Sarah Krantz, Peter T Toth, Deborah E. Leckband, Andrei Karginov, Jalees Rehman
Endothelial adherens junctions (AJs) are critical for the regulation of vascular barrier integrity and undergo dis-assembly during inflammatory injury, thus causing vascular leakiness. AJ re-assembly is thus necessary for restoration of the endotheli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2bf4c77760cee74e7d7a620522675a4f
https://doi.org/10.1101/2022.11.11.516184
https://doi.org/10.1101/2022.11.11.516184
Publikováno v:
Biomacromolecules. 23(10)
Polymers designed to stabilize proteins exploit direct interactions or crowding, but mechanisms underlying increased stability or reduced aggregation are rarely established. Alginate is widely used to encapsulate proteins for drug delivery and tissue
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b52096c6ef9a867eeaf7267a825b08c8
https://pubmed.ncbi.nlm.nih.gov/36054903
https://pubmed.ncbi.nlm.nih.gov/36054903
Publikováno v:
Molecular biology of the cell. 33(11)
Increased tension on VE-cadherin (VE-cad) complexes activates adaptive cell stiffening and local cytoskeletal reinforcement--two key signatures of intercellular mechanotransduction. Here we demonstrate that tugging on VE-cad receptors initiates a cas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d2ccfcea8a9a4f537a92740b1000ef3
https://pubmed.ncbi.nlm.nih.gov/35653290
https://pubmed.ncbi.nlm.nih.gov/35653290
Publikováno v:
Biophysical Journal. 122:90a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fd03c262357a65e7fad16d46567e9721
https://doi.org/10.1016/j.bpj.2022.11.688
https://doi.org/10.1016/j.bpj.2022.11.688