Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Deborah E. Devor"'
Autor:
Deborah E. Devor-Henneman, Rivka A. Rachel, Takuro Nakamura, Yuriko Saiki, Sally E. Spence, Nancy A. Jenkins, Tomoyuki Hisa, Jerrold M. Ward, Haruo Kutsuna, Masami Fujita, Lino Tessarollo, Neal G. Copeland
Publikováno v:
The EMBO Journal. 23:450-459
Meis1 and Hoxa9 expression is upregulated by retroviral integration in murine myeloid leukemias and in human leukemias carrying MLL translocations. Both genes also cooperate to induce leukemia in a mouse leukemia acceleration assay, which can be expl
Autor:
Bhalchandra A. Diwan, Deborah E. Devor, John D. Shaughnessy, Michael P. Waalkes, Michael K. Abshire
Publikováno v:
Carcinogenesis. 17:1349-1356
Cadmium (Cd), a carcinogenic metal in humans and rodents, has been shown to transform cells in vitro. Cd in certain instances can also be anti-carcinogenic. The effects of Cd have been studied in different mammalian cell culture systems, where it has
Publikováno v:
Toxicologic Pathology. 21:261-273
Although breast implant materials have been tested in laboratory species since the early 1950s, a standardized evaluation system does not currently exist in which human-made polymers are exposed directly to the mammary milieu of female animals. The p
Autor:
Sabine Rehm, Deborah E. Devor
Publikováno v:
Journal of Cancer Research and Clinical Oncology. 120:41-50
4-Ipomenaol (IPO) has been shown to induceP-450-mediated necrosis of Clara cells in experimental animals, and clinical trials were initiated to treat people with bronchioloalveolar cancers with this novel drug. We therefore performed experiments to e
Autor:
Jerrold M. Ward, Konstantin H. Dragnev, Raymond W. Nims, Bhalchandra A. Diwan, Mark Steven Miller, Collins R. Jones, Jerry M. Rice, Ronald A. Lubet, Deborah E. Devor
Publikováno v:
Biochemical Pharmacology. 43:1079-1087
Phenobarbital (PB) and certain structurally-related compounds induce a variety of hepatic drug-metabolizing enzymes in many strains of rats. Thus, following administration of PB (300, 500 ppm), barbital (BB, 1500 ppm) or 5-ethyl-5-phenylhydantoin (EP
Publikováno v:
Carcinogenesis. 13:1541-1547
The progression of hepatocellular adenomas to carcinomas has been less well documented in mice than in rats. We studied progression of spontaneous and chemically induced hepatocellular adenomas in male C3H/HeNCr mice by image analysis. Spontaneous le
Autor:
John D. Minna, Draginja Djurickovic, Gregory W. Alvord, Jerrold M. Ward, Michael I. Lerman, Nicole L. Morris, Dorothea McAreavey, Michael A. Rogawski, Ming Hui Wei, Deborah E. Devor-Henneman, Boning Gao, Vandana Sachdev, James A. Richardson, Melissa K. Banks, Lameh Fananapazir, Sergey Ivanov, Lino Tessarollo
CACNA2D2 is a putative tumor suppressor gene located in the human chromosome 3p21.3 region that shows frequent allelic imbalances in lung, breast, and other cancers. The alpha2delta-2 protein encoded by the gene is a regulatory subunit of voltage-dep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b3712963dd6b8513c1ad27897ad4403
https://europepmc.org/articles/PMC1618598/
https://europepmc.org/articles/PMC1618598/
Publikováno v:
Toxicologic pathology. 32
As many as 5% of human cancers appear to be of hereditable etiology. Of the more than 50 characterized familial cancer syndromes, most involve disease affecting multiple organs and many can be traced to one or more abnormalities in specific genes. St
Autor:
Lucy M. Anderson, Alan O. Perantoni, Takayuki Enomoto, Jerry M. Rice, Gregory S. Buzard, Deborah E. Devor
Publikováno v:
Journal of cancer research and clinical oncology. 125(12)
Transplacentally initiated schwannomas in mice and rats arise preferentially in the Gasserian ganglion of the trigeminal nerve and spinal root ganglia, while those of the Syrian golden hamster most commonly occur subcutaneously. Rat and hamster schwa
Autor:
Bhalchandra A. Diwan, Lee F. Dove, Jerry M. Rice, Carl D. Reed, Alan O. Perantoni, Deborah E. Devor, Takayuki Enomoto, Gregory S. Buzard, Tadashi Hongyo
Publikováno v:
Journal of cancer research and clinical oncology. 125(10)
Peripheral nerve tumors (PNT) and melanomas induced transplacentally on day 14 of gestation in Syrian golden hamsters by N-nitrosoethylurea were analyzed for activated oncogenes by the NIH 3T3 transfection assay, and for mutations in the neu oncogene