Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Deborah E. Crawford"'
Autor:
Deborah E. Crawford
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 13, Iss 1, Pp 1850-1856 (2017)
Sonochemistry, i.e., the application of mechanical energy in the form of sound waves, has recently been recognised for its similarity to mechanochemistry and is now included under the umbrella term of mechanochemistry. Typically, due to the hypothesi
Externí odkaz:
https://doaj.org/article/2ae644478af5469d8e283fef1afd6aad
Autor:
Deborah E. Crawford
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 13, Iss 1, Pp 65-75 (2017)
Herein, the benefits which extrusion can provide for the automated continuous synthesis of organic compounds are highlighted. Extrusion is a well-established technique that has a vital role in the manufacturing processes of polymers, pharmaceuticals
Externí odkaz:
https://doaj.org/article/e992b4e9fc154684b360caece9ab8631
Publikováno v:
Cao, Q, Crawford, D E, Shi, C & James, S L 2020, ' Greener Dye Synthesis: Continuous, Solvent-Free Synthesis of Commodity Perylene Diimides by Twin-Screw Extrusion ', Angewandte Chemie International Edition, vol. 59, no. 11, pp. 4478 . https://doi.org/10.1002/anie.201913625
A continuous, scalable, and solvent-free method for the synthesis of various naphthalic imides and perylene diimides (PDIs) using twin-screw extrusion (TSE) is reported. Using TSE, naphthalic imides were obtained quantitatively without the need for e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d8c0efc79b8a0e888b46ce4070dd166
https://doi.org/10.1002/ange.201913625
https://doi.org/10.1002/ange.201913625
Autor:
Francesca Greenwell, Michael E. Briggs, Deborah E. Crawford, Rebecca L. Greenaway, Michael C. Brand, Benjamin D. Egleston, Andrew I. Cooper, Stuart L. James
Publikováno v:
CHEMICAL SCIENCE
The continuous and scalable synthesis of a porous organic cage (CC3), obtained through a 10-component imine polycondensation between triformylbenzene and a vicinal diamine, was achieved using twin screw extrusion (TSE). Compared to both batch and flo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cce51adbd793a4f9386e80f24ff4758
https://doi.org/10.1039/d0sc01858a
https://doi.org/10.1039/d0sc01858a
Autor:
Or Galant, Giacomo Cerfeda, Aaron S. McCalmont, Stuart L. James, Andrea Porcheddu, Francesco Delogu, Deborah E. Crawford, Evelina Colacino, Sabrina Spatari
Publikováno v:
Galant, O, Cerfeda, G, McCalmont, A S, James, S L, Porcheddu, A, Delogu, F, Crawford, D E, Colacino, E & Spatari, S 2022, ' Mechanochemistry can reduce life cycle environmental impacts of manufacturing active pharmaceutical ingredients ', ACS Sustainable Chemistry & Engineering, vol. 10, no. 4, pp. 1430–1439 . https://doi.org/10.1021/acssuschemeng.1c06434
The scale-up of mechanochemical methods could play a transformative role in making manufacturing processes in the pharmaceutical industry greener by eliminating solvent use and recovery. Combined with energy-efficient continuous processing that conso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54ddf7bcb075fb2591c4e314e265e4e6
https://pure.qub.ac.uk/en/publications/7b4e9ccf-f5e3-4936-b3e0-195b00260941
https://pure.qub.ac.uk/en/publications/7b4e9ccf-f5e3-4936-b3e0-195b00260941
Autor:
Mario G. Del Pópolo, Peter N. Horton, Stuart L. James, Sergio F. Fonrouge, Deborah E. Crawford, José L. Borioni, Benjamin P. Hutchings, Simon J. Coles, Francesca M. Alexander
Publikováno v:
Alexander, F M, Fonrouge, S F, Borioni, J L, Del Pópolo, M G, Horton, P N, Coles, S J, Hutchings, B P, Crawford, D E & James, S L 2021, ' Noria and its derivatives as hosts for chemically and thermally robust Type II porous liquids ', Chemical Science, no. 42, pp. 14230-14240 . https://doi.org/10.1039/d1sc03367k
Chemical Science
Chemical Science
Porous Liquids (PLs) are a new class of material that possess both fluidity and permanent porosity. As such they can act as enhanced, selective solvents and may ultimately find applications which are not possible for porous solids, such as continuous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d6c7ae4a0a03894f566ef1bd64e478e
https://pure.qub.ac.uk/en/publications/noria-and-its-derivatives-as-hosts-for-chemically-and-thermally-robust-type-ii-porous-liquids(2f1e3c22-9798-48b1-8f39-9b7806c7f5dc).html
https://pure.qub.ac.uk/en/publications/noria-and-its-derivatives-as-hosts-for-chemically-and-thermally-robust-type-ii-porous-liquids(2f1e3c22-9798-48b1-8f39-9b7806c7f5dc).html
Autor:
Csaba Jobbágy, Andrea Deák, Attila Demeter, Péter Ábrányi-Balogh, Pál Szabó, Deborah E. Crawford, Evelina Colacino, Jaroslav Cihlář, David Virieux, Ladislav Čelko
Publikováno v:
Dalton Transactions. 2021, vol. 50, issue 38, p. 13337-13344.
A mechanochemical method is reported for the synthesis of Au(diphos)X complexes of diphosphine (diphos = XantPhos and N-XantPhos) ligands and halide ions (X = Cl and I). The Au(XantPhos)X (1: X = Cl; 2: X = I) and Au(N-XantPhos)Cl (3) complexes exhib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8957e53e37909beeb823f76196bf3111
https://pubmed.ncbi.nlm.nih.gov/34608904
https://pubmed.ncbi.nlm.nih.gov/34608904
Publikováno v:
Trends in Chemistry
Trends in Chemistry, 2021, 3 (5), pp.335-339. ⟨10.1016/j.trechm.2021.02.008⟩
Trends in Chemistry, 2021, 3 (5), pp.335-339. ⟨10.1016/j.trechm.2021.02.008⟩
Mechanochemistry provides an environmentally sustainable approach to prepare and process molecules and materials and offers a new research space full of opportunities. However, its full industrial potential has not yet been realized. Herein, we discu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a28fe0192cbe0b81b4f1f6e7213d6c71
https://hal.umontpellier.fr/hal-03227543
https://hal.umontpellier.fr/hal-03227543
Publikováno v:
McCalmont, A S, Ruiz Estrada, G A, Lagunas, M C, Al-Jamal, W T & Crawford, D 2020, ' Cytotoxicity of Mechanochemically Prepared Cu(II) Complexes ', ACS Sustainable Chemistry & Engineering . https://doi.org/10.1021/acssuschemeng.0c04950
Despite evidence that mechanochemistry has the potential to be a revolutionary manufacturing technique, the Pharma industry is still reluctant to introduce these new technologies into their manufacturing processes. Therefore, it is now time to pionee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::932d6fe9697c4f01a913ee977fc8f394
https://pure.qub.ac.uk/en/publications/cytotoxicity-of-mechanochemically-prepared-cuii-complexes(b4943673-1d4b-4945-986d-dd9412c04dbb).html
https://pure.qub.ac.uk/en/publications/cytotoxicity-of-mechanochemically-prepared-cuii-complexes(b4943673-1d4b-4945-986d-dd9412c04dbb).html
Autor:
Evelina Colacino, Francesco Delogu, Deborah E. Crawford, Andrea Porcheddu, Stuart L. James, Aaron S. McCalmont
Publikováno v:
ACS Sustainable Chemistry & Engineering
ACS Sustainable Chemistry & Engineering, American Chemical Society, 2020, 8 (32), pp.12230-12238. ⟨10.1021/acssuschemeng.0c03816⟩
Crawford, D E, Porcheddu, A, McCalmont, A S, Delogu, F, James, S L & Colacino, E 2020, ' Solvent-Free, Continuous Synthesis of Hydrazone-Based Active Pharmaceutical Ingredients by Twin-Screw Extrusion ', ACS Sustainable Chemistry & Engineering, vol. 8, no. 32, pp. 12230-12238 . https://doi.org/10.1021/acssuschemeng.0c03816
ACS Sustainable Chemistry & Engineering, American Chemical Society, 2020, 8 (32), pp.12230-12238. ⟨10.1021/acssuschemeng.0c03816⟩
Crawford, D E, Porcheddu, A, McCalmont, A S, Delogu, F, James, S L & Colacino, E 2020, ' Solvent-Free, Continuous Synthesis of Hydrazone-Based Active Pharmaceutical Ingredients by Twin-Screw Extrusion ', ACS Sustainable Chemistry & Engineering, vol. 8, no. 32, pp. 12230-12238 . https://doi.org/10.1021/acssuschemeng.0c03816
Twin-screw extrusion (TSE) was used to synthesize hydantoin-based active pharmaceutical ingredients (APIs) such as nitrofurantoin and dantrolene, employing minimal or no solvent. Postsynthetic workup was not required. This work demonstrates that solv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cc04608cc1c8bdae81bb2b677135a30
https://hal.umontpellier.fr/hal-02935135
https://hal.umontpellier.fr/hal-02935135