Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Deborah E. Burgin"'
Autor:
James A. Swenberg, Linda S. Birnbaum, Grace E. Kissling, Nigel J. Walker, Yo Chan Jeong, Lawrence L. Kupper, Deborah E. Burgin, Mayetri Gupta
Publikováno v:
Free Radical Biology and Medicine. 45:585-591
Oxidative DNA damage is one of the key events thought to be involved in mutation and cancer. The present study examined the accumulation of M1dG, 3-(2'-deoxy-beta-D-erythro-pentofuranosyl)-pyrimido[1,2-a]-purin-10(3H)-one, DNA adducts after single do
Autor:
R. W. Setzer, Janet J. Diliberto, Linda S. Birnbaum, Ralph J. Smialowicz, Wanda C. Williams, Deborah E. Burgin
Publikováno v:
Toxicology. 197:15-22
One of the most sensitive and reproducible immunotoxic endpoints of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) exposure is suppression of the antibody response to sheep red blood cells (SRBCs) in mice. Immunosuppression occurs in concert with hepatom
Autor:
Janet J. Diliberto, Linda S. Birnbaum, Narayanan Kannan, Prasada Rao S. Kodavanti, Deborah E. Burgin, Ethel C. Derr-Yellin
Publikováno v:
Environmental Health Perspectives
Aroclor 1254 is a commercial mixture of polychlorinated biphenyls (PCBs), which is defined as being 54% chlorine by weight. However, the congener composition varies from lot to lot. Two lots which have been used in toxicity studies, 124-191 and 6024
Autor:
Narayanan Kannan, Linda S. Birnbaum, Prasada Rao S. Kodavanti, Nobuyoshi Yamashita, Thomas R. Ward, Hugh A. Tilson, Ethel C. Derr-Yellin, Deborah E. Burgin
Publikováno v:
Environmental Health Perspectives
Aroclor 1254 is a widely studied commercial polychlorinated biphenyl (PCB) mixture which, by definition, contains 54% chlorine by weight. Recent reports indicate substantial differences in the congener composition among Aroclor lots and hence their b
Publikováno v:
Toxicology and Applied Pharmacology. 159:52-64
TCDD is the prototype and most potent member of the highly lipophilic polyhalogenated aromatic hydrocarbons (PHAHs), which are persistent and ubiquitous environmental contaminants. In both acute and subchronic animal studies, there is a specific accu
Publikováno v:
Biochemical and Biophysical Research Communications. 236:431-433
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD, dioxin), most potent of the polyhalogenated aromatic hydrocarbons, has been studied in a variety of genetically normal species. Transgenic mice lacking a cytochrome P450 1A2 gene were used to study the influ
Autor:
Deborah E. Burgin
Publikováno v:
International Journal of Toxicology. 21:511-512