Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Deborah E Daniels"'
Autor:
Joseph Hawksworth, Timothy J Satchwell, Marjolein Meinders, Deborah E Daniels, Fiona Regan, Nicole M Thornton, Marieangela C Wilson, Johannes GG Dobbe, Geert J Streekstra, Kongtana Trakarnsanga, Kate J Heesom, David J Anstee, Jan Frayne, Ashley M Toye
Publikováno v:
EMBO Molecular Medicine, Vol 10, Iss 6, Pp 1-11 (2018)
Abstract Regular blood transfusion is the cornerstone of care for patients with red blood cell (RBC) disorders such as thalassaemia or sickle‐cell disease. With repeated transfusion, alloimmunisation often occurs due to incompatibility at the level
Externí odkaz:
https://doaj.org/article/9af938bdb64040d3b9bf6a27b7e9cbb8
Autor:
Deborah E. Daniels, Ivan Ferrer-Vicens, Joseph Hawksworth, Tatyana N. Andrienko, Elizabeth M. Finnie, Natalie S. Bretherton, Daniel C. J. Ferguson, A. Sofia. F. Oliveira, Jenn-Yeu A. Szeto, Marieangela C. Wilson, John N. Brewin, Jan Frayne
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract β-thalassemia is a prevalent genetic disorder causing severe anemia due to defective erythropoiesis, with few treatment options. Studying the underlying molecular defects is impeded by paucity of suitable patient material. In this study we
Externí odkaz:
https://doaj.org/article/9939683767224f40b2a842f9297fb596
Autor:
Deborah E. Daniels, Damien J. Downes, Ivan Ferrer-Vicens, Daniel C. J. Ferguson, Belinda K. Singleton, Marieangela C. Wilson, Kongtana Trakarnsanga, Ryo Kurita, Yukio Nakamura, David J. Anstee, Jan Frayne
Publikováno v:
Haematologica, Vol 109, Iss 1 (2024)
Externí odkaz:
https://doaj.org/article/4d782518f626402dbd7d20dbf0bff7ad
Autor:
Kongtana Trakarnsanga, Daniel Ferguson, Deborah E. Daniels, Rebecca E. Griffiths, Marieangela C. Wilson, Kathryn E. Mordue, Abi Gartner, Tatyana N. Andrienko, Annabel Calvert, Alison Condie, Angela McCahill, Joanne C. Mountford, Ashley M. Toye, David J. Anstee, Jan Frayne
Publikováno v:
Stem Cell Research & Therapy, Vol 10, Iss 1, Pp 1-10 (2019)
Abstract Background Pluripotent stem cells are attractive progenitor cells for the generation of erythroid cells in vitro as have expansive proliferative potential. However, although embryonic (ESC) and induced pluripotent (iPSC) stem cells can be in
Externí odkaz:
https://doaj.org/article/ab66fdf60c4c4d08878afa9f330cc664
Autor:
Daniel C.J. Ferguson, Juraidah Haji Mokim, Marjolein Meinders, Edmund R.R. Moody, Tom A. Williams, Sarah Cooke, Kongtana Trakarnsanga, Deborah E. Daniels, Ivan Ferrer-Vicens, Deborah Shoemark, Chartsiam Tipgomut, Katherine A. Macinnes, Marieangela C. Wilson, Belinda K. Singleton, Jan Frayne
Publikováno v:
Haematologica, Vol 106, Iss 11 (2020)
Human ZNF648 is a novel poly C-terminal C2H2 zinc finger (ZnF) protein identified amongst the most dysregulated proteins in erythroid cells differentiated from induced pluripotent stem cells. Its nuclear localization and structure indicate it is like
Externí odkaz:
https://doaj.org/article/74d92bd41183494184a640381d6306d2
Autor:
Deborah E. Daniels, Damien J. Downes, Ivan Ferrer-Vicens, Daniel C. J. Ferguson, Belinda K. Singleton, Marieangela C. Wilson, Kongtana Trakarnsanga, Ryo Kurita, Yukio Nakamura, David J. Anstee, Jan Frayne
Publikováno v:
Haematologica, Vol 105, Iss 8 (2020)
Externí odkaz:
https://doaj.org/article/45b08dbb99fb489a9a8511a89e4e0a31
Autor:
David J. Anstee, Phillip A. Lewis, Daniel Ramos Jiménez, Tatyana N Andrienko, Kathryn E. Mordue, Deborah E. Daniels, Marieangela C. Wilson, Ivan Ferrer-Vicens, Yukio Nakamura, Rebecca E. Griffiths, Daniel C. J. Ferguson, Ryo Kurita, Maurice A. Canham, Kongtana Trakarnsanga, Nicola Cogan, Jan Frayne, Katherine A. MacInnes
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 22, Iss, Pp 26-39 (2021)
Daniels, D, Ferguson, D C J, Trakarnsanga, T, Cogan, N M, MacInnes, K, Andrienko, T N, Ferrer Vicens, I, Wilson, M C, Anstee, D J & Frayne, J 2021, ' Reproducible immortalization of erythroblasts from multiple stem cell sources provides approach for sustainable RBC therapeutics ', Molecular Therapy-Methods and Clinical Development, vol. 22, pp. 26-39 . https://doi.org/10.1016/j.omtm.2021.06.002
Molecular Therapy. Methods & Clinical Development
Daniels, D, Ferguson, D C J, Trakarnsanga, T, Cogan, N M, MacInnes, K, Andrienko, T N, Ferrer Vicens, I, Wilson, M C, Anstee, D J & Frayne, J 2021, ' Reproducible immortalization of erythroblasts from multiple stem cell sources provides approach for sustainable RBC therapeutics ', Molecular Therapy-Methods and Clinical Development, vol. 22, pp. 26-39 . https://doi.org/10.1016/j.omtm.2021.06.002
Molecular Therapy. Methods & Clinical Development
Developing robust methodology for the sustainable production of red blood cells in vitro is essential for providing an alternative source of clinical-quality blood, particularly for individuals with rare blood group phenotypes. Immortalized erythroid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afecb6f33a3bd09a2f78b76a3eade7c7
https://doi.org/10.1016/j.omtm.2021.06.002
https://doi.org/10.1016/j.omtm.2021.06.002
Autor:
Deborah E Daniels, Ivan Ferrer-Vicens, J Hawksworth, Tatyana N Andrienko, Elizabeth M Finnie, Daniel C J Ferguson, A. Sofia F. Oliveira, Jenn-Yeu A. Szeto, Marieangela C Wilson, Jan Frayne
β-thalassemia is a prevalent genetic disorder causing severe anemia due to defective erythropoiesis, with few treatment options. Studying the underlying molecular defects is impeded by paucity of suitable patient material. In this study we created h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f5852f8ee726a0d767ffc1a8c93246a3
https://doi.org/10.1101/2022.09.01.506225
https://doi.org/10.1101/2022.09.01.506225
Autor:
Deborah K. Shoemark, Daniel C. J. Ferguson, Ivan Ferrer-Vicens, Marieangela C. Wilson, Kongtana Trakarnsanga, Sarah Cooke, Marjolein Meinders, Deborah E. Daniels, Katherine A. MacInnes, Juraidah Haji Mokim, Jan Frayne, Tom A. Williams, Chartsiam Tipgomut, Edmund R. R. Moody, Belinda K. Singleton
Publikováno v:
Haematologica. 106:2859-2873
Human ZNF648 is a novel poly C-terminal C2H2 zinc finger (ZnF) protein identified amongst the most dysregulated proteins in erythroid cells differentiated from induced pluripotent stem cells. Its nuclear localization and structure indicate it is like
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::216591e5722a228ade2e1527a0877313
https://doi.org/10.3324/haematol.2020.256347
https://doi.org/10.3324/haematol.2020.256347
Autor:
Darya Deen, Jan Frayne, Matthias Mann, Daniel C. J. Ferguson, Helena Ayyub, Vasiliki Samara, Michelle L. Holland, Falk Butter, Jacqueline A. Sloane-Stanley, Douglas Vernimmen, Ivan Ferrer-Vicens, David Garrick, Deborah E. Daniels
Publikováno v:
Deen, D, Butter, F, Daniels, D, Ferrer-Vicens, I, Vernimmen, D, Garrick, D, Holland, M L, Samara, V, Sloane-Stanley, J A, Ayyub, H, Mann, M, Frayne, J & Ferguson, D 2021, ' Identification of the transcription factor MAZ as a regulator of erythropoiesis ', Blood Advances, pp. 3002-3015 . https://doi.org/10.1182/bloodadvances.2021004609
Deen, D, Daniels, D E, Ferrer-Vicens, I, Ferguson, D C J, Frayne, J, Vernimmen, D & al., E 2021, ' Identification of the transcription factor MAZ as a regulator of erythropoiesis ', Blood Advances, vol. 5, no. 15, pp. 3002-3015 . https://doi.org/10.1182/bloodadvances.2021004609
Deen, D, Daniels, D E, Ferrer-Vicens, I, Ferguson, D C J, Frayne, J, Vernimmen, D & al., E 2021, ' Identification of the transcription factor MAZ as a regulator of erythropoiesis ', Blood Advances, vol. 5, no. 15, pp. 3002-3015 . https://doi.org/10.1182/bloodadvances.2021004609
Erythropoiesis requires a combination of ubiquitous and tissue-specific transcription factors (TFs). Here, through DNA affinity purification followed by mass spectrometry, we have identified the widely expressed protein MAZ (Myc-associated zinc finge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d1803f22fa6b8a0383e0dd594d4ce65
https://pubmed.ncbi.nlm.nih.gov/35298619
https://pubmed.ncbi.nlm.nih.gov/35298619