Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Deborah D. Chin"'
Publikováno v:
Bioactive Materials, Vol 27, Iss , Pp 327-336 (2023)
Atherosclerosis is a chronic inflammatory disease that is characterized by the build-up of lipid-rich plaques in the arterial walls. The standard treatment for patients with atherosclerosis is statin therapy aimed to lower serum lipid levels. Despite
Externí odkaz:
https://doaj.org/article/8d68199ccb7b496cae3264e7bea1a82d
Publikováno v:
Frontiers in Digital Health, Vol 4 (2022)
During atherosclerosis, vascular smooth muscle cells (VSMCs) undergo a phenotypic transition from a healthy contractile state into pathological phenotypes including a proliferative and migratory, synthetic phenotype and osteochondrogenic-like phenoty
Externí odkaz:
https://doaj.org/article/dbdcd0d2e2b748f2b088691ddae1eb18
Publikováno v:
The AAPS Journal. 23
Cardiovascular disease (CAD) due to atherosclerosis is a major cause of death worldwide. The development of atherosclerosis involves intercellular communication facilitated by exosomes secreted from vascular endothelial cells (VECs), vascular smooth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eec41a3c1af5ecf9d0618e8c8e8f3ed3
https://doi.org/10.1208/s12248-021-00621-w
https://doi.org/10.1208/s12248-021-00621-w
Collagenase-Cleavable Peptide Amphiphile Micelles as a Novel Theranostic Strategy in Atherosclerosis
Autor:
Christopher Poon, Eun Ji Chung, Russell E. Jacobs, Deborah D Chin, Zhangjingyi Jiang, Jackson Cook, Johan Joo, Jonathan Wang, Naomi S Sta Maria, Noah Trac
Publikováno v:
Adv Ther (Weinh)
Atherosclerosis is an inflammatory disease characterized by plaques that can cause sudden myocardial infarction upon rupture. Such rupture-prone plaques have thin fibrous caps due to collagenase degradation, and a noninvasive diagnostic tool and targ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8e87559c457685034a97d9f49c52f92
https://pubmed.ncbi.nlm.nih.gov/34295964
https://pubmed.ncbi.nlm.nih.gov/34295964
Autor:
Victor Ong, Christopher Poon, Deborah D Chin, Zhangjingyi Jiang, Anastasia Plotkin, Eun Ji Chung, Gregory A. Magee, Kayley Cheng, Johan Joo, Jonathan Wang
Publikováno v:
Biomaterials
In atherosclerosis, resident vascular smooth muscle cells (VSMCs) in the blood vessels become highly plastic and undergo phenotypic switching from the quiescent, contractile phenotype to the migratory and proliferative, synthetic phenotype. Additiona
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f1849a9fdb7adac9696662ca8ae978a
https://pubmed.ncbi.nlm.nih.gov/33892346
https://pubmed.ncbi.nlm.nih.gov/33892346
Autor:
Margot Mel de Fontenay, Deborah D Chin, Jonathan Wang, Gregory A. Magee, Anastasia Plotkin, Eun Ji Chung
Publikováno v:
J Mater Chem B
Atherosclerosis is a chronic disease characterized by the formation of calcified, arterial plaques. Microcalcifications (5 μm to 100 μm), mainly composed of hydroxyapatite (HA, Ca(5)(PO(4))(3)(OH)), develop in the fibrous caps of atherosclerotic pl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84f4e169c146a88ee698290484f5dece
https://pubmed.ncbi.nlm.nih.gov/31553027
https://pubmed.ncbi.nlm.nih.gov/31553027
Autor:
Huang Y; Department of Biomedical Engineering, University of Southern California, Los Angeles, CA 90089, USA., Wang J; Department of Biomedical Engineering, University of Southern California, Los Angeles, CA 90089, USA., Mancino V; Department of Medicine, Division of Nephrology and Hypertension, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.; USC/UKRO Kidney Research Center, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA., Pham J; Department of Medicine, Division of Nephrology and Hypertension, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.; USC/UKRO Kidney Research Center, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA., O'Grady C; Department of Biomedical Engineering, University of Southern California, Los Angeles, CA 90089, USA., Li H; Department of Medicine, Division of Nephrology and Hypertension, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.; USC/UKRO Kidney Research Center, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA., Jiang K; Department of Biomedical Engineering, University of Southern California, Los Angeles, CA 90089, USA., Chin D; Department of Biomedical Engineering, University of Southern California, Los Angeles, CA 90089, USA., Poon C; Department of Biomedical Engineering, University of Southern California, Los Angeles, CA 90089, USA., Ho PY; Department of Medicine, Division of Nephrology and Hypertension, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.; USC/UKRO Kidney Research Center, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA., Gyarmati G; Department of Physiology and Neuroscience, and Medicine, Zilkha Neurogenetic Institute, University of Southern California, Los Angeles, CA 90033, USA., Peti-Peterdi J; Department of Physiology and Neuroscience, and Medicine, Zilkha Neurogenetic Institute, University of Southern California, Los Angeles, CA 90033, USA., Hallows KR; Department of Medicine, Division of Nephrology and Hypertension, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.; USC/UKRO Kidney Research Center, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA., Chung EJ; Department of Biomedical Engineering, University of Southern California, Los Angeles, CA 90089, USA.; Department of Medicine, Division of Nephrology and Hypertension, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.; Department of Chemical Engineering and Materials Science, University of Southern California, Los Angeles, CA 90089, USA.; Department of Surgery, Division of Vascular Surgery and Endovascular Therapy, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.; Department of Stem Cell Biology and Regenerative Medicine, University of Southern California, Los Angeles, CA 90089, USA.; Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA 90033, USA.; Bridge Institute, University of Southern California, Los Angeles, CA 90089, USA.
Publikováno v:
PNAS nexus [PNAS Nexus] 2024 May 10; Vol. 3 (5), pp. pgae187. Date of Electronic Publication: 2024 May 10 (Print Publication: 2024).
Autor:
Jenike AE; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland., Bunkelman B; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland., Perzel Mandell KA; Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland., Oduor CI; Department of Pathology and Laboratory Medicine, Warren Alpert Medical School, Brown University, Providence, Rhode Island., Chin D; Department of Pathology and Laboratory Medicine, Warren Alpert Medical School, Brown University, Providence, Rhode Island., Mair D; Department of Biomedical Engineering, Johns Hopkins University, Baltimore, Maryland., Jenike KM; Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland., Kim DH; Department of Biomedical Engineering, Johns Hopkins University, Baltimore, Maryland; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland., Bailey JA; Department of Pathology and Laboratory Medicine, Warren Alpert Medical School, Brown University, Providence, Rhode Island., Rafailovich MH; Department of Materials Science and Chemical Engineering, Stony Brook University, Stony Brook, New York., Rosenberg AZ; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland., Halushka MK; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland. Electronic address: mhalush1@jhmi.edu.
Publikováno v:
Laboratory investigation; a journal of technical methods and pathology [Lab Invest] 2023 Jul; Vol. 103 (7), pp. 100133. Date of Electronic Publication: 2023 Mar 28.
Autor:
Wang J; Department of Biomedical Engineering, University of Southern California, Los Angeles, CA, USA., Chin D; Department of Biomedical Engineering, University of Southern California, Los Angeles, CA, USA., Poon C; Department of Biomedical Engineering, University of Southern California, Los Angeles, CA, USA., Mancino V; Department of Medicine, Division of Nephrology and Hypertension, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA; USC/UKRO Kidney Research Center, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA., Pham J; Department of Medicine, Division of Nephrology and Hypertension, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA; USC/UKRO Kidney Research Center, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA., Li H; Department of Medicine, Division of Nephrology and Hypertension, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA; USC/UKRO Kidney Research Center, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA., Ho PY; Department of Medicine, Division of Nephrology and Hypertension, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA; USC/UKRO Kidney Research Center, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA., Hallows KR; Department of Biomedical Engineering, University of Southern California, Los Angeles, CA, USA; Department of Medicine, Division of Nephrology and Hypertension, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA; USC/UKRO Kidney Research Center, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA., Chung EJ; Department of Biomedical Engineering, University of Southern California, Los Angeles, CA, USA; Department of Medicine, Division of Nephrology and Hypertension, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA; Department of Chemical Engineering and Materials Science, University of Southern California, Los Angeles, CA, USA; Department of Surgery, Division of Vascular Surgery and Endovascular Therapy, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA; Department of Stem Cell Biology and Regenerative Medicine, University of Southern California, Los Angeles, CA, USA; Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA, USA; Bridge Institute, University of Southern California, Los Angeles, CA, USA. Electronic address: eunchung@usc.edu.
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society [J Control Release] 2021 Jan 10; Vol. 329, pp. 1198-1209. Date of Electronic Publication: 2020 Oct 28.
Autor:
Wong BS; Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, MD, USA.; Institute for NanoBioTechnology, Johns Hopkins University, Baltimore, MD, USA., Shah SR; Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Department of Neurosurgery, Mayo Clinic, Jacksonville, FL, USA., Yankaskas CL; Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, MD, USA.; Institute for NanoBioTechnology, Johns Hopkins University, Baltimore, MD, USA., Bajpai VK; Department of Chemical and Systems Biology, Stanford University, Stanford, CA, USA.; Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA, USA., Wu PH; Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, MD, USA.; Institute for NanoBioTechnology, Johns Hopkins University, Baltimore, MD, USA., Chin D; Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, MD, USA., Ifemembi B; Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, MD, USA.; Institute for NanoBioTechnology, Johns Hopkins University, Baltimore, MD, USA., ReFaey K; Department of Neurosurgery, Mayo Clinic, Jacksonville, FL, USA., Schiapparelli P; Department of Neurosurgery, Mayo Clinic, Jacksonville, FL, USA., Zheng X; Department of Embryology, Carnegie Institution for Science, Baltimore, MD, USA., Martin SS; Marlene and Stewart Greenebaum National Cancer Institute Comprehensive Cancer Center, Department of Physiology, University of Maryland School of Medicine, Baltimore, MD, USA., Fan CM; Department of Embryology, Carnegie Institution for Science, Baltimore, MD, USA., Quiñones-Hinojosa A; Department of Neurosurgery, Mayo Clinic, Jacksonville, FL, USA. Quinones-Hinojosa.Alfredo@mayo.edu., Konstantopoulos K; Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, MD, USA. konstant@jhu.edu.; Institute for NanoBioTechnology, Johns Hopkins University, Baltimore, MD, USA. konstant@jhu.edu.; Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, USA. konstant@jhu.edu.; Department of Oncology, Johns Hopkins University, Baltimore, MD, USA. konstant@jhu.edu.
Publikováno v:
Nature biomedical engineering [Nat Biomed Eng] 2021 Jan; Vol. 5 (1), pp. 26-40. Date of Electronic Publication: 2020 Sep 28.