Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Deborah Croom"'
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. 37:1626-1633
Spreading depolarization-induced focal dendritic swelling (beading) is an early hallmark of neuronal cytotoxic edema. Pyramidal neurons lack membrane-bound aquaporins posing a question of how water enters neurons during spreading depolarization. Rece
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab76e2d593d8086ca3a71e112f12a733
https://doi.org/10.1177/0271678x16639328
https://doi.org/10.1177/0271678x16639328
Publikováno v:
The Journal of Neuroscience. 35:12172-12187
Spreading depolarizations (SDs) are waves of sustained neuronal and glial depolarization that propagate massive disruptions of ion gradients through the brain. SD is associated with migraine aura and recently recognized as a novel mechanism of injury
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d96cc6477f983e0e176cbd8afe5a7dca
https://doi.org/10.1523/jneurosci.0400-15.2015
https://doi.org/10.1523/jneurosci.0400-15.2015
Autor:
Leah, Fitzsimmons, Andrew J, Boyce, Wenbin, Wei, Catherine, Chang, Deborah, Croom-Carter, Rosemary J, Tierney, Marco J, Herold, Andrew I, Bell, Andreas, Strasser, Gemma L, Kelly, Martin, Rowe
Publikováno v:
Cell Death and Differentiation
While the association of Epstein–Barr virus (EBV) with Burkitt lymphoma (BL) has long been recognised, the precise role of the virus in BL pathogenesis is not fully resolved. EBV can be lost spontaneously from some BL cell lines, and these EBV-loss
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a80451670f6afea75e0bed658ea69eaa
https://pubmed.ncbi.nlm.nih.gov/28960205
https://pubmed.ncbi.nlm.nih.gov/28960205
Autor:
Andre S. Ribeiro, Jeremy Sword, Mikhail Kislin, Leonard Khiroug, Eero Lihavainen, Dmytro Toptunov, Sergei A. Kirov, Heikki Rauvala, Ioulia V. Fomitcheva, Evgeny Pryazhnikov, Deborah Croom
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 37(2)
Mitochondria play a variety of functional roles in cortical neurons, from metabolic support and neuroprotection to the release of cytokines that trigger apoptosis. In dendrites, mitochondrial structure is closely linked to their function, and fragmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf406bc3ab331fc22d2044204d1a86c6
https://pubmed.ncbi.nlm.nih.gov/28077713
https://pubmed.ncbi.nlm.nih.gov/28077713
Autor:
Anemari Horvat, Dou Yu, Deborah Croom, Zala Lužnik, Yang D. Teng, Sergei A. Kirov, Marko Kreft, Robert Zorec, Xiang Zeng, Jamie E. Anderson, Nina Vardjan
Publikováno v:
Glia.
Edema in the central nervous system can rapidly result in life-threatening complications. Vasogenic edema is clinically manageable, but there is no established medical treatment for cytotoxic edema, which affects astrocytes and is a primary trigger o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea948cdb171af2e249eaea3e0da3402a
https://doi.org/10.1002/glia.22981
https://doi.org/10.1002/glia.22981
Publikováno v:
Glia. 60:1709-1720
Spreading depolarizations are a key event in the pathophysiology of stroke, resulting in rapid dendritic beading, which represents acute damage to synaptic circuitry. The impact of spreading depolarizations on the real-time injury of astrocytes durin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6842c457baccfc0f9cdbec10fbcc51b
https://doi.org/10.1002/glia.22390
https://doi.org/10.1002/glia.22390
Autor:
Nina, Vardjan, Anemari, Horvat, Jamie E, Anderson, Dou, Yu, Deborah, Croom, Xiang, Zeng, Zala, Lužnik, Marko, Kreft, Yang D, Teng, Sergei A, Kirov, Robert, Zorec
Publikováno v:
Glia. 64(6)
Edema in the central nervous system can rapidly result in life-threatening complications. Vasogenic edema is clinically manageable, but there is no established medical treatment for cytotoxic edema, which affects astrocytes and is a primary trigger o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::60f9c60733941f7c33d2f1dcf4508f6d
https://pubmed.ncbi.nlm.nih.gov/27018061
https://pubmed.ncbi.nlm.nih.gov/27018061
Autor:
Ki Jung Kim, Víctor M. Blanco, Jennifer A. Iddings, Javier E. Stern, Deborah Croom, Jessica A. Filosa, Sergei A. Kirov
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 35(21)
Basal and activity-dependent cerebral blood flow changes are coordinated by the action of critical processes, including cerebral autoregulation, endothelial-mediated signaling, and neurovascular coupling. The goal of our study was to determine whethe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6708b4f8a0d0c7959b1cbe11fa7f6bbd
https://pubmed.ncbi.nlm.nih.gov/26019339
https://pubmed.ncbi.nlm.nih.gov/26019339
In traumatic brain injury mechanical forces applied to the cranium and brain cause irreversible primary neuronal and astroglial damage associated with terminal dendritic beading and spine loss representing acute damage to synaptic circuitry. Oedema d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::219b3791484d14675acef13d8e117cf3
https://europepmc.org/articles/PMC3634194/
https://europepmc.org/articles/PMC3634194/
Publikováno v:
Glia. 59(11)
Microglia are the resident immune cells in the brain. Under normal conditions, resting ramified microglia constantly extend and retract fine processes while performing immunological surveillance. In ischemia, microglia become activated as demonstrate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e8f6142991c2d41ab91c67837bf5e3e
https://pubmed.ncbi.nlm.nih.gov/21800362
https://pubmed.ncbi.nlm.nih.gov/21800362