Zobrazeno 1 - 10
of 196
pro vyhledávání: '"Deborah C. Rice"'
Publikováno v:
Neurotoxicology and Teratology. 32:313-328
The National Research Council (NRC) of the National Academies of Science recently published a report of its vision of toxicity testing in the 21st century. The report proposes that the current toxicity testing paradigm that depends upon whole-animal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::64580fc30741a5d4fea6c3f857ebf928
https://doi.org/10.1016/j.ntt.2010.02.002
https://doi.org/10.1016/j.ntt.2010.02.002
Autor:
Deborah C. Rice, Vincent P. Markowski, Elizabeth A. Reeve, W. Douglas Thompson, Kristen D. Onos, Mina Assadollahzadeh
Publikováno v:
Environmental Health Perspectives
Background After several decades of commercial use, the flame-retardant chemicals polybrominated diphenyl ethers (PBDEs) and their metabolites are pervasive environmental contaminants and are detected in the human body. Decabrominated diphenyl ether
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10cf557b2895ac505242b9043e791844
https://doi.org/10.1289/ehp.11814
https://doi.org/10.1289/ehp.11814
Autor:
Deborah C. Rice, Gary Ginsberg
Publikováno v:
Environmental Health Perspectives
Background Bisphenol A (BPA) risks are being evaluated by many regulatory bodies because exposure is widespread and the potential exists for toxicity at low doses. Objective We evaluated evidence that BPA is cleared more rapidly in humans than in rat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c894fbfd4264ea9af31f83b71024a868
https://doi.org/10.1289/ehp.0901010
https://doi.org/10.1289/ehp.0901010
Autor:
Lina Adwan, Nasser H. Zawia, Deborah C. Rice, Debomoy K. Lahiri, Christopher A. McPherson, G. Jean Harry, Remi Dosunmu, Riyaz Basha, Jinfang Wu, Bryan Maloney
Publikováno v:
Journal of Alzheimer's Disease. 18:211-230
Alzheimer's disease (AD) is characterized by plaques of amyloid-beta (Abeta) peptide, cleaved from amyloid-beta protein precursor (AbetaPP). Our hypothesis is that lifespan profiles of AD-associated mRNA and protein levels in monkeys would differ fro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4932c3d53e5f2ea3c2534a934fb165e7
https://doi.org/10.3233/jad-2009-1138
https://doi.org/10.3233/jad-2009-1138
Publikováno v:
Environmental Health Perspectives
Background There is increasing evidence in humans and in experimental animals for a relationship between exposure to specific environmental chemicals and perturbations in levels of critically important thyroid hormones (THs). Identification and prope
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06dd7ae4acb9c17d3850c77da5d021ff
https://doi.org/10.1289/ehp.0800247
https://doi.org/10.1289/ehp.0800247
Autor:
Ted Schettler, Claudia S. Miller, Donna Mergler, Elise Miller, Deborah C. Rice, M. Christopher Newland, Deborah A. Cory-Slechta, Bernard Weiss, Steven G. Gilbert
Publikováno v:
NeuroToxicology. 29:883-890
Neurotoxicology is entering a new phase in how it views and practices risk assessment. Perhaps more than any of the other disciplines that comprise the science of toxicology, it has been compelled to consider a daunting array of factors other than th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffd2b4f0bf1179e122f7d78be6f09f33
https://doi.org/10.1016/j.neuro.2008.04.004
https://doi.org/10.1016/j.neuro.2008.04.004
Autor:
Kevin M. Crofton, Sarah J. Janssen, Dale Hattis, Robert W. Luebke, Mark R. Miller, Christopher J. Portier, George V. Alexeeff, Paul M. D. Foster, Daniel A. Axelrad, Amy D. Kyle, Lauren Zeise, Linda S. Birnbaum, Tracey J. Woodruff, Kathryn Z. Guyton, John J. Vandenberg, Gregory G. Miller, Jackie M. Schwartz, Henry A. Anderson, Susan Y. Euling, R. Thomas Zoeller, Frédéric Y. Bois, Earl L. Gray, Gina Solomon, Vincent Cogliano, Deborah C. Rice, Michael I. Luster, Dori R. Germolec
Publikováno v:
Environmental Health Perspectives
Environmental health perspectives, vol 116, iss 11
Environmental health perspectives, vol 116, iss 11
BACKGROUND: Assessing adverse effects from environmental chemical exposure is integral to public health policies. Toxicology assays identifying early biological changes from chemical exposure are increasing our ability to evaluate links, between earl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e2503ea520d396e8010fd7ed7606b79
http://europepmc.org/articles/PMC2592280
http://europepmc.org/articles/PMC2592280
Autor:
Amy Anderson, G. Jean Harry, Riyaz Basha, Deborah C. Rice, Debomoy K. Lahiri, Bryan Maloney, Brian Brock, Nasser H. Zawia, Katie DiPalma
Publikováno v:
Journal of Alzheimer's Disease. 13:71-80
Alzheimer's disease is characterized by amyloid-beta peptide (Abeta)-loaded plaques in the brain. Abeta is a cleavage fragment of amyloid-beta protein precursor (APP) and over production of APP may lead to amyloidogenesis. The regulatory region of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cf168cce5977ab234b29b59d4b19017
https://doi.org/10.3233/jad-2008-13108
https://doi.org/10.3233/jad-2008-13108
Autor:
Deborah C. Rice, Aleece Herlihy, Vincent P. Markowski, Elizabeth A. Reeve, W. Douglas Thompson, R. Thomas Zoeller
Publikováno v:
Neurotoxicology and Teratology. 29:511-520
After several decades of commercial use, the flame retardant chemicals polybrominated diphenyl ethers (PBDEs) and their metabolites have become pervasive environmental contaminants with a global distribution. PBDEs have entered the food chain and inc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb5dc9c45c45ded3739577bab8ca4746
https://doi.org/10.1016/j.ntt.2007.03.061
https://doi.org/10.1016/j.ntt.2007.03.061
Publikováno v:
Environmental Health Perspectives
Perchlorate is a powerful oxidant that is used in rocket fuel, munitions, blasting operations, and fireworks [National Research Council (NRC) 2005]. Environmental contamination has occurred at military installations, at facilities that make perchlora
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b55ef2e320d92936352af3b6121051b
https://doi.org/10.1289/ehp.9533
https://doi.org/10.1289/ehp.9533