Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Deborah Bourc'his"'
Autor:
David Gentien, Elnaz Saberi-Ansari, Nicolas Servant, Ariane Jolly, Pierre de la Grange, Fariba Némati, Géraldine Liot, Simon Saule, Aurélie Teissandier, Deborah Bourc’his, Elodie Girard, Jennifer Wong, Julien Masliah-Planchon, Erkan Narmanli, Yuanlong Liu, Emma Torun, Rebecca Goulancourt, Manuel Rodrigues, Laure Villoing Gaudé, Cécile Reyes, Matéo Bazire, Thomas Chenegros, Emilie Henry, Audrey Rapinat, Mylene Bohec, Sylvain Baulande, Radhia M’kacher, Eric Jeandidier, André Nicolas, Giovanni Ciriello, Raphael Margueron, Didier Decaudin, Nathalie Cassoux, Sophie Piperno-Neumann, Marc-Henri Stern, Johan Harmen Gibcus, Job Dekker, Edith Heard, Sergio Roman-Roman, Joshua J. Waterfall
Publikováno v:
Cell Reports, Vol 42, Iss 9, Pp 113132- (2023)
Summary: Uveal melanoma (UM) is a rare cancer resulting from the transformation of melanocytes in the uveal tract. Integrative analysis has identified four molecular and clinical subsets of UM. To improve our molecular understanding of UM, we perform
Externí odkaz:
https://doaj.org/article/1572404d6b2643f898a51a4a704e001b
Autor:
Juliane Glaser, Julian Iranzo, Maud Borensztein, Mattia Marinucci, Angelica Gualtieri, Colin Jouhanneau, Aurélie Teissandier, Carles Gaston-Massuet, Deborah Bourc'his
Publikováno v:
eLife, Vol 11 (2022)
Genomic imprinting refers to the mono-allelic and parent-specific expression of a subset of genes. While long recognized for their role in embryonic development, imprinted genes have recently emerged as important modulators of postnatal physiology, n
Externí odkaz:
https://doaj.org/article/4e59277598dd4ccbbd4bcaaa22690b54
Publikováno v:
Mobile DNA, Vol 10, Iss 1, Pp 1-12 (2019)
Abstract Background Sequencing technologies give access to a precise picture of the molecular mechanisms acting upon genome regulation. One of the biggest technical challenges with sequencing data is to map millions of reads to a reference genome. Th
Externí odkaz:
https://doaj.org/article/b9471866bf614dce9be7a58e897f8340
Autor:
Courtney W. Hanna, Raquel Pérez-Palacios, Lenka Gahurova, Michael Schubert, Felix Krueger, Laura Biggins, Simon Andrews, Maria Colomé-Tatché, Deborah Bourc’his, Wendy Dean, Gavin Kelsey
Publikováno v:
Genome Biology, Vol 20, Iss 1, Pp 1-17 (2019)
Abstract Background Genomic imprinting is an epigenetic phenomenon that allows a subset of genes to be expressed mono-allelically based on the parent of origin and is typically regulated by differential DNA methylation inherited from gametes. Imprint
Externí odkaz:
https://doaj.org/article/1f13e69e51574ec4ae0c64c683c949cc
Autor:
Roberta Ragazzini, Raquel Pérez-Palacios, Irem H. Baymaz, Seynabou Diop, Katia Ancelin, Dina Zielinski, Audrey Michaud, Maëlle Givelet, Mate Borsos, Setareh Aflaki, Patricia Legoix, Pascal W. T. C. Jansen, Nicolas Servant, Maria-Elena Torres-Padilla, Deborah Bourc’his, Pierre Fouchet, Michiel Vermeulen, Raphaël Margueron
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-18 (2019)
Polycomb Repressive Complex 2 (PRC2) plays critical roles in transcriptional silencing during development. Here the authors identify EZHIP as a cofactor of PRC2 expressed predominantly in the gonads, finding that EZHIP limits the enzymatic activity o
Externí odkaz:
https://doaj.org/article/840ba9a727064edb97ff673ade34b357
Publikováno v:
eLife, Vol 8 (2019)
During early mammalian development, the chromatin landscape undergoes profound transitions. The Zdbf2 gene—involved in growth control—provides a valuable model to study this window: upon exit from naïve pluripotency and prior to tissue different
Externí odkaz:
https://doaj.org/article/afd19ac36c754f5ab0c7aa47ff94940a
Publikováno v:
eLife, Vol 7 (2018)
The discovery of genomic imprinting by Davor Solter, Azim Surani and co-workers in the mid-1980s has provided a foundation for the study of epigenetic inheritance and the epigenetic control of gene activity and repression, especially during developme
Externí odkaz:
https://doaj.org/article/f48d97c820094e85bdab6d943460af8f
Autor:
Isabel Iglesias-Platas, Alex Martin-Trujillo, Davide Cirillo, Franck Court, Amy Guillaumet-Adkins, Cristina Camprubi, Deborah Bourc'his, Kenichiro Hata, Robert Feil, Gian Tartaglia, Philippe Arnaud, David Monk
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e38907 (2012)
Genomic imprinting is a complex epigenetic mechanism of transcriptional control that utilizes DNA methylation and histone modifications to bring about parent-of-origin specific monoallelic expression in mammals. Genes subject to imprinting are often
Externí odkaz:
https://doaj.org/article/75a973f630334971b059ce2ecb05af1d