Zobrazeno 1 - 10
of 341
pro vyhledávání: '"Deborah Blacker"'
Autor:
Mohamed Taha, Lee H Schwamm, Deborah Blacker, Lidia M V R Moura, Joseph P Newhouse, Mamoon Habib, Victor Lomachinsky, Peter Hadar
Publikováno v:
BMJ Neurology Open, Vol 6, Iss 2 (2024)
Background The National Institutes of Health Stroke Scale (NIHSS) scores have been used to evaluate acute ischaemic stroke (AIS) severity in clinical settings. Through the International Classification of Diseases, Tenth Revision Code (ICD-10), docume
Externí odkaz:
https://doaj.org/article/1b8fe1cf69b34ef8aefdccd778005173
Publikováno v:
npj Digital Medicine, Vol 6, Iss 1, Pp 1-12 (2023)
Abstract Antidepressant selection is largely a trial-and-error process. We used electronic health record (EHR) data and artificial intelligence (AI) to predict response to four antidepressants classes (SSRI, SNRI, bupropion, and mirtazapine) 4 to 12
Externí odkaz:
https://doaj.org/article/139df4b556e740c181ab8de98d1e4cfa
Autor:
Marie-Laure Charpignon, Bella Vakulenko-Lagun, Bang Zheng, Colin Magdamo, Bowen Su, Kyle Evans, Steve Rodriguez, Artem Sokolov, Sarah Boswell, Yi-Han Sheu, Melek Somai, Lefkos Middleton, Bradley T. Hyman, Rebecca A. Betensky, Stan N. Finkelstein, Roy E. Welsch, Ioanna Tzoulaki, Deborah Blacker, Sudeshna Das, Mark W. Albers
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Previous observational studies of the diabetes drugs metformin vs. sulfonylureas have yielded mixed results about whether metformin reduces the risk of dementia, relative to the sulfonylureas. Here, the authors apply a novel competing risks approach
Externí odkaz:
https://doaj.org/article/6c6653ae33484933bc4f68d1094c553c
Autor:
Pia Kivisäkk, Becky C. Carlyle, Thadryan Sweeney, Bianca A. Trombetta, Kathryn LaCasse, Leena El-Mufti, Idil Tuncali, Lori B. Chibnik, Sudeshna Das, Clemens R. Scherzer, Keith A. Johnson, Bradford C. Dickerson, Teresa Gomez-Isla, Deborah Blacker, Derek H. Oakley, Matthew P. Frosch, Bradley T. Hyman, Anahit Aghvanyan, Pradeepthi Bathala, Christopher Campbell, George Sigal, Martin Stengelin, Steven E. Arnold
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
BackgroundThe last few years have seen major advances in blood biomarkers for Alzheimer's Disease (AD) with the development of ultrasensitive immunoassays, promising to transform how we diagnose, prognose, and track progression of neurodegenerative d
Externí odkaz:
https://doaj.org/article/6404f04c0c8f4fdea79ffcc9b0fb11c5
Autor:
Ayush Noori, Colin Magdamo, Xiao Liu, Tanish Tyagi, Zhaozhi Li, Akhil Kondepudi, Haitham Alabsi, Emily Rudmann, Douglas Wilcox, Laura Brenner, Gregory K Robbins, Lidia Moura, Sahar Zafar, Nicole M Benson, John Hsu, John R Dickson, Alberto Serrano-Pozo, Bradley T Hyman, Deborah Blacker, M Brandon Westover, Shibani S Mukerji, Sudeshna Das
Publikováno v:
Journal of Medical Internet Research, Vol 24, Iss 8, p e40384 (2022)
BackgroundElectronic health records (EHRs) with large sample sizes and rich information offer great potential for dementia research, but current methods of phenotyping cognitive status are not scalable. ObjectiveThe aim of this study was to evaluate
Externí odkaz:
https://doaj.org/article/0a175401157e49f1a9a96ecde69cc1ca
Autor:
Dearbhla M. Kelly, Christopher D. Anderson, Deborah Blacker, Bruce L. Miller, Anand Viswanathan
Publikováno v:
Frontiers in Neurology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/0c1a022e2b2845ccbd961a3c72fe61a5
Autor:
Alvin S. Das, Robert W. Regenhardt, Meike W. Vernooij, Deborah Blacker, Andreas Charidimou, Anand Viswanathan
Publikováno v:
Journal of Stroke, Vol 21, Iss 2, Pp 121-138 (2019)
Cerebral small vessel disease (CSVD) is a common group of neurological conditions that confer a significant burden of morbidity and mortality worldwide. In most cases, CSVD is only recognized in its advanced stages once its symptomatic sequelae devel
Externí odkaz:
https://doaj.org/article/61a966e327544948af1b2e1dac27888d
Autor:
Sarah Floud, PhD, Angela Balkwill, MSc, Siân Sweetland, DPhil, Anna Brown, MSc, Elsa Mauricio Reus, PhD, Albert Hofman, ProfMD, Deborah Blacker, ProfScD, Mika Kivimaki, ProfFMedSci, Jane Green, ProfDPhil, Richard Peto, ProfFRS, Gillian K Reeves, ProfPhD, Valerie Beral, ProfFRS
Publikováno v:
The Lancet Public Health, Vol 6, Iss 2, Pp e116-e123 (2021)
Summary: Background: Although dementia is associated with non-participation in cognitive and social activities, this association might merely reflect the consequences of dementia, rather than any direct effect of non-participation on the subsequent i
Externí odkaz:
https://doaj.org/article/061bea5d88b04825ad660b24ee724c32
Autor:
J. Scott Roberts, Rebecca Ferber, Deborah Blacker, Malia Rumbaugh, Joshua D. Grill, for the Advisory Group on Risk Evidence Education for Dementia (AGREED)
Publikováno v:
Alzheimer’s & Dementia: Translational Research & Clinical Interventions, Vol 7, Iss 1, Pp n/a-n/a (2021)
Abstract Introduction This study describes practices for disclosing individual research results to participants in Alzheimer's disease research. Methods An online survey of clinical core leaders at National Institutes of Health‐funded Alzheimer's D
Externí odkaz:
https://doaj.org/article/c12028fe49074538b228169fcd80d941
Autor:
Eric E Smith, Alona Muzikansky, Cheryl R McCreary, Saima Batool, Anand Viswanathan, Bradford C Dickerson, Keith Johnson, Steven M Greenberg, Deborah Blacker
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0191345 (2018)
Hypertension is the strongest modifiable risk factor for subcortical ischemic changes and is also a risk factor for Alzheimer's dementia. We used neuroimaging to investigate the pathological basis of early cognitive symptoms in patients with hyperten
Externí odkaz:
https://doaj.org/article/63e09b415b8140c99bf9acf98d346347