Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Deborah Baxter"'
Publikováno v:
Strategies. 35:54-56
Autor:
Lu Zhang, Katragadda Subbarao, Graham J. Durant, Deborah Baxter, Elizabeth Yost, Peter I. Nagy, Michael E. Perlman, James B. Fischer, David Berlove, Oved Amitay, Sonia Connaughton, Jun Qing Guo, Lain-Yen Hu, Michel Maillard, Robert N. McBurney
Publikováno v:
Journal of Medicinal Chemistry. 41:3048-3061
In the present investigation, the rationale for the design, synthesis, and biological evaluation of potent inhibitors of neuronal Na+ channels is described. N,N'-diaryl- and N-aryl-N-aralkylguanidine templates were locked in conformations mimicking t