Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Deborah Balzano"'
Autor:
Henrik Watz, Oliver Kornmann, Aida Emirova, Dave Singh, Deborah Balzano, Marie Anna Nandeuil, Gera L. Jellema, Michele Bassi, Brian Leaker, Ebenezer K. Afolabi, Mirco Govoni, Kai Michael Beeh, Germano Lucci
Publikováno v:
Journal of Cellular and Molecular Medicine
Chronic obstructive pulmonary disease (COPD) patients with higher eosinophil counts are associated with increased clinical response to phosphodiesterase‐4‐inhibitors (PDE4i). However, the underlying inflammatory mechanisms associated with this in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea956a2038b6766503396ec80c0fec9b
https://doi.org/10.1111/jcmm.16146
https://doi.org/10.1111/jcmm.16146
COPD sputum eosinophils: relationship to blood eosinophils and the effect of inhaled PDE4 inhibition
Autor:
Oliver Kornmann, Brendan Colgan, Aida Emirova, Brian Leaker, Debora Santoro, Dave Singh, Marie Anna Nandeuil, Deborah Balzano, Henrik Watz, Germano Lucci, Mirco Govoni, Kai Michael Beeh
Publikováno v:
The European Respiratory Journal
article-version (VoR) Version of Record
article-version (VoR) Version of Record
Patients with COPD who have higher eosinophil numbers in the airways and peripheral blood demonstrate a greater clinical response to inhaled corticosteroids (ICS) [1–3]. Furthermore, the effect of the oral phosphodiesterase-4 (PDE4) inhibitor roflu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bb32bed2c3874cb172492928179b145
http://europepmc.org/articles/PMC7406856
http://europepmc.org/articles/PMC7406856
Autor:
Mohamad-Ali Fawal, Joshua Y. C. Yang, Deborah Balzano, José Vicente Velázquez, Nabil Djouder, Joaquín Pastor, Daniel Lietha, Ramón Campos-Olivas, Clara M. Santiveri
Publikováno v:
Journal of Biological Chemistry. 290:24975-24985
Protein kinase B (PKB/Akt) is an important mediator of signals that control various cellular processes including cell survival, growth, proliferation, and metabolism. PKB promotes these processes by phosphorylating many cellular targets, which trigge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::becbdf970ace7bf5f8734cd9ffdfe961
https://doi.org/10.1074/jbc.m115.651570
https://doi.org/10.1074/jbc.m115.651570
Publikováno v:
Chemistry & Biology. (8):966-975
SummaryProtein kinases control virtually every aspect of normal and pathological cell physiology and are considered ideal targets for drug discovery. Most kinase inhibitors target the ATP binding site and interact with residue of a hinge loop connect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb947a2c3d39458fe9c11542b35fe602