Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Deborah B. Doroshow"'
Autor:
Yüksel Ürün, Syed A. Hussain, Ziad Bakouny, Daniel Castellano, Saadettin Kılıçkap, Gilberto Morgan, Rana R. Mckay, Kevin Pels, Andrew Schmidt, Deborah B. Doroshow, Fábio Schütz, Laurence Albiges, Gilberto Lopes, James W. F. Catto, Solange Peters, Toni K. Choueiri
Publikováno v:
JCO Global Oncology, Vol , Iss 6, Pp 1248-1257 (2020)
PURPOSE To understand readiness measures taken by oncologists to protect patients and health care workers from the novel coronavirus (COVID-19) and how their clinical decision making was influenced by the pandemic. METHODS An online survey was conduc
Externí odkaz:
https://doaj.org/article/10c712e7f144403792a261a26b22e458
Publikováno v:
The Cancer Journal. 28:381-386
The WEE1 kinase family plays a crucial role in cell cycle regulation and DNA damage response pathways in malignant cells. Inhibition of WEE1 effectively overrides G2 cell cycle arrest and results in the accumulation of extensive DNA damage within div
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84b72cbba30c90843ffa7e0a15852c27
https://doi.org/10.1097/ppo.0000000000000613
https://doi.org/10.1097/ppo.0000000000000613
Autor:
Jeremy L. Warner, Gary H. Lyman, Yu Shyr, Huili Zhu, Albert C. Yeh, Zhuoer Xie, Julie T. Wu, Sumit A. Shah, Gary K. Schwartz, Andrew Schmidt, Lidia Schapira, Sanjay G. Revankar, Matthew M. Puc, Nathan A. Pennell, Adam J. Olszewski, Sanjay Mishra, Christopher A. Lemmon, Ali Raza Khaki, Jessica E. Hawley, Balazs Halmos, Thorvardur R. Halfdanarson, Shilpa Gupta, Sanjay Goel, Matthew D. Galsky, Christopher R. Friese, Leslie A. Fecher, Dimitrios Farmakiotis, Pamela C. Egan, Deborah B. Doroshow, Ziad Bakouny, Jonathan Arcobello, Michael A. Thompson, Brian I. Rini, Corrie A. Painter, Petros Grivas, Gilberto de Lima Lopes, Toni K. Choueiri, Brendan J. Lee, Samuel M. Rubinstein, Chih-Yuan Hsu, Nicole M. Kuderer, Dimpy P. Shah, Orestis A. Panagiotou, Solange Peters, Donna R. Rivera
Among 2,186 U.S. adults with invasive cancer and laboratory-confirmed SARS-CoV-2 infection, we examined the association of COVID-19 treatments with 30-day all-cause mortality and factors associated with treatment. Logistic regression with multiple ad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8fe3e91742eed8cd6e89916ca9852e1b
https://doi.org/10.1158/2159-8290.c.6548182.v1
https://doi.org/10.1158/2159-8290.c.6548182.v1
Autor:
Jeremy L. Warner, Gary H. Lyman, Yu Shyr, Huili Zhu, Albert C. Yeh, Zhuoer Xie, Julie T. Wu, Sumit A. Shah, Gary K. Schwartz, Andrew Schmidt, Lidia Schapira, Sanjay G. Revankar, Matthew M. Puc, Nathan A. Pennell, Adam J. Olszewski, Sanjay Mishra, Christopher A. Lemmon, Ali Raza Khaki, Jessica E. Hawley, Balazs Halmos, Thorvardur R. Halfdanarson, Shilpa Gupta, Sanjay Goel, Matthew D. Galsky, Christopher R. Friese, Leslie A. Fecher, Dimitrios Farmakiotis, Pamela C. Egan, Deborah B. Doroshow, Ziad Bakouny, Jonathan Arcobello, Michael A. Thompson, Brian I. Rini, Corrie A. Painter, Petros Grivas, Gilberto de Lima Lopes, Toni K. Choueiri, Brendan J. Lee, Samuel M. Rubinstein, Chih-Yuan Hsu, Nicole M. Kuderer, Dimpy P. Shah, Orestis A. Panagiotou, Solange Peters, Donna R. Rivera
Supplemental tables, figures, and list of participants
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::119af38d85e5df3672cf35f4d86f04b9
https://doi.org/10.1158/2159-8290.22536610
https://doi.org/10.1158/2159-8290.22536610
Autor:
Swati B. Gupta, Charles J. Robbins, David L. Rimm, Jon Zugazagoitia, Wei Wei, Deborah B. Doroshow, Blythe J.S. Adamson
Publikováno v:
J Thorac Oncol
BACKGROUND: For patients with non-small cell lung cancer (NSCLC) receiving immune checkpoint inhibitors, PD-L1 tumor proportion score has been validated as a predictive biomarker for improved overall survival. However, its histology-specific predicti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9368eabdc1e6712cf6cab3d958c80e60
https://doi.org/10.1016/j.jtho.2021.07.032
https://doi.org/10.1016/j.jtho.2021.07.032
Autor:
Thomas Urban Marron, Nelson M. LaMarche, Matthew D. Park, Samarth Hegde, Bailey Fitzgerald, Clotilde Hennequin, Raphael Mattiuz, Meriem Belabed, Jessica Le Berichel, Barbara Maier, Nicole Hall, Justin Miller, Deborah B. Doroshow, Nicholas Rohs, Rajwanth Veluswamy, Nicholas Venturini, Jorge E. Gomez, Christian Rolfo, David Yankelevitz, Udit Chaddha, Timothy Harkin, Mary B. Beasley, Seunghee Kim-schulze, Sacha Gnjatic, Fred R. Hirsch, Miriam Merad
Publikováno v:
Cancer Research. 83:CT199-CT199
Type-2 cytokines are hypothesized to promote an immune-permissive milieu for cancer to grow. Through scRNAseq and CITEseq on human non-small cell lung cancer (NSCLC) and the krasG12Dp53−/− lung cancer model we previously described a tumor-enriche
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a12f4ac573c7f84f15a8ade44468174
https://doi.org/10.1158/1538-7445.am2023-ct199
https://doi.org/10.1158/1538-7445.am2023-ct199
Autor:
Deborah B. Doroshow, Lynette M. Sholl, Fred R. Hirsch, Ming-Sound Tsao, Keith M. Kerr, Sacha Gnjatic, Sheena Bhalla, Ignacio I. Wistuba, David L. Rimm, Mary Beth Beasley
Publikováno v:
Nature Reviews Clinical Oncology. 18:345-362
Immune-checkpoint inhibitors targeting PD-1 or PD-L1 have already substantially improved the outcomes of patients with many types of cancer, although only 20-40% of patients derive benefit from these new therapies. PD-L1, quantified using immunohisto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::26aec47c49a50691389c4e8bd3b9aa6a
https://doi.org/10.1038/s41571-021-00473-5
https://doi.org/10.1038/s41571-021-00473-5
Publikováno v:
The Cancer Journal. 26:507-516
Immune checkpoint inhibitors (ICIs) have revolutionized the treatment paradigm for advanced non-small cell lung cancer (NSCLC). Although certain patients achieve significant, long-lasting responses from checkpoint blockade, the majority of patients w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36c6e5186813cf947d4965e3fb07586f
https://doi.org/10.1097/ppo.0000000000000483
https://doi.org/10.1097/ppo.0000000000000483
Autor:
Zhuoer Xie, Julie T Wu, Huili Zhu, Deborah B. Doroshow, Yu Shyr, Thorvardur R. Halfdanarson, Jessica Hawley, Sanjay Mishra, Lidia Schapira, Leslie A. Fecher, Sanjay Goel, Samuel M. Rubinstein, Petros Grivas, Pamela C Egan, Solange Peters, Sumit A. Shah, Gary K. Schwartz, Michael A. Thompson, Jonathan T Arcobello, Chih-Yuan Hsu, Christopher R. Friese, Dimitrios Farmakiotis, Corrie A. Painter, Matthew D. Galsky, Nicole M. Kuderer, Nathan A. Pennell, Ziad Bakouny, Sanjay G. Revankar, Brian I. Rini, Albert C. Yeh, Donna R. Rivera, Jeremy L. Warner, Dimpy P. Shah, Brendan J Lee, Ali Raza Khaki, Adam J. Olszewski, Matthew Puc, Orestis A. Panagiotou, Gary H. Lyman, Christopher Lemmon, Balazs Halmos, Andrew Schmidt, Toni K. Choueiri, Gilberto Lopes, Shilpa Gupta
Publikováno v:
Cancer Discovery
Cancer discovery, vol. 10, no. 10, pp. 1514-1527
Cancer discovery, vol. 10, no. 10, pp. 1514-1527
In a large observational study in patients with COVID-19 and cancer, survival was not significantly influenced by receipt of COVID-19 treatments, except hydroxychloroquine plus any other treatment, which was associated with reduced survival.
Amo
Amo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c19be86f094f92aafe7221786c1b2cd6
https://doi.org/10.1158/2159-8290.cd-20-0941
https://doi.org/10.1158/2159-8290.cd-20-0941
Autor:
Dimitrios Farmakiotis, Susie Owenby, Arturo Loaiza-Bonilla, Mansi R. Shah, Matthew Puc, Vadim S. Koshkin, Ahmad Daher, Prakash Peddi, Cameron Rink, Heloisa P. Soares, Eneida R. Nemecek, Mehmet Asim Bilen, Sanjay Mishra, Lidia Schapira, Amit Verma, Ali Raza Khaki, Chih-Yuan Hsu, Sandy DiLullo, Mark Bonnen, Jeanna Knoble, Carla Casulo, Umit Topaloglu, Jorge A. Garcia, Geoffrey Shouse, Praveen Vikas, Clarke A. Low, Archana Ajmera, George D. Demetri, Leyre Zubiri, Grace Glace, Shannon K. McWeeney, Susan Yackzan, Pamela C Egan, Rachel P. Rosovsky, Salvatore Del Prete, Anthony P. Gulati, Lane R. Rosen, Andy Futreal, Merry Jennifer Markham, Sabitha Prabhakaran, Alicia K. Morgans, Sarah Nagle, Lisa Weissmann, Albert C. Yeh, Ziad Bakouny, Stephanie Berg, David Gill, Marcus Messmer, Ryan Nguyen, Terence Duane Rhodes, Vikram M. Narayan, Matthew D. Galsky, Arielle Elkrief, Lori J. Rosenstein, Roy S. Herbst, Justin Shaya, Thorvardur R. Halfdanarson, Douglas B. Johnson, Orestis A. Panagiotou, Sanjay G. Revankar, Toni K. Choueiri, Yu Shyr, Fiona Busser, Kaitlin M. Kelleher, Nicole M. Kuderer, Paul L. Weinstein, Anup Kasi, Grace Shaw, Adam J. Olszewski, Catherine Curran, Samuel M. Rubinstein, Angelo Cabal, Michael H. Bar, John F. Deeken, Vivek Subbiah, Abdul Hai Mansoor, Hina Khan, Rana R. McKay, Catherine Stratton, Saurabh Dahiya, Marc A. Rovito, John Philip, Sanjay Shete, Oscar K. Serrano, Julie Fu, Daniel W. Bowles, Candice Schwartz, Tian Zhang, Pier Vitale Nuzzo, Eric H. Bernicker, Wenxin Xu, Genevieve M. Boland, Sarah Wall, Babar Bashir, Solange Peters, Neeta K. Venepalli, Sandeep H. Mashru, William A. Wood, Anne H. Angevine, Mary F. Mulcahy, Gilberto Lopes, Justin F. Gainor, Jessica Hawley, Monika Joshi, Christopher R. Friese, Navid Hafez, Heather H. Nelson, Gregory J. Riely, Jordan Kharofa, Nilo Azad, Chintan Shah, Gerald Batist, Mary Salazar, Rosemary Zacks, Alice Zhou, Lawrence E. Feldman, Paul Fu, Gary H. Lyman, Nathaniel Bouganim, John A. Steinharter, Shilpa Gupta, Matthias Weiss, Peter Paul Yu, Susan Van Loon, Jamie Stratton, Karen Vega-Luna, Tyler Masters, Christopher Lemmon, Aakash Desai, Bryan A. Faller, Jessica M. Clement, Zhuoer Xie, Keith Stockerl-Goldstein, Corrie A. Painter, Gabrielle Bouchard, Rulla M. Tamimi, Daruka Mahadevan, Rimma Belenkaya, Jill S. Barnholtz-Sloan, Jarushka Naidoo, Amelie G. Ramirez, Philip E. Lammers, Elizabeth A. Griffiths, Michael J. Gurley, X. Li, Jonathan Riess, Syed A. Ahmad, Daniel Blake Flora, Salma K. Jabbour, Jared D. Acoba, Neeraj Agarwal, Ang Li, Sarah Mushtaq, Firas Wehbe, Tanios Bekaii-Saab, Donald C. Vinh, Emily Hsu, Ryan Monahan, Petros Grivas, Harry Menon, John M. Nakayama, Janice M. Mehnert, Elizabeth Marie Wulff-Burchfield, Sara Matar, Paul E. Oberstein, Mary M. Pasquinelli, Axel Grothey, Jack West, John C. Leighton, Dawn L. Hershman, Leslie A. Fecher, Aditya Bardia, Sumit A. Shah, Barbara Logan, Kerry L. Reynolds, Michael A. Thompson, Robert L. Rice, Erin Cook, Trisha Wise-Draper, Christine Bestvina, Daniel Castellano, Paolo Caimi, K. M.Steve Lo, Ruben A. Mesa, Maheen Z. Abidi, Alvaro G. Menendez, Daniel G. Stover, Colleen Lewis, Bertrand Routy, Deborah B. Doroshow, Carmen C. Solorzano, M. Wasif Saif, Rohit Bishnoi, Michael Glover, David D. Chism, Briana Barrow, Christopher McNair, Dimpy P. Shah, Erin A. Gillaspie, Andrea J. Zimmer, Andrew Schmidt, Jessica K. Altman, Michelle Marcum, Rawad Elias, Balazs Halmos, Karen Stauffer, Gayathri Nagaraj, Ardaman Shergill, Mark E. Dailey, Catherine Handy Marshall, Pramod K. Srivastava, Shuchi Gulati, Alokkumar Jha, Mateo Bover Larroya, Mark A. Lewis, Young Soo Rho, James L. Chen, Eli Van Allen, Julie Tsu Yu Wu, Antonio Giordano, Amit Kulkarni, Joerg Rathmann, Donna R. Rivera, Narjust Duma, Maryam B. Lustberg, Theresa M. Carducci, Jeremy L. Warner, Elizabeth Robilotti, Patricia LoRusso, Rohit Jain, Amit Sanyal, Nizar M. Tannir, Kent Hoskins, Nathan A. Pennell, Brian I. Rini, Suki Subbiah
Publikováno v:
Lancet, vol. 395, no. 10241, pp. 1907-1918
The Lancet
The Lancet
Summary Background Data on patients with COVID-19 who have cancer are lacking. Here we characterise the outcomes of a cohort of patients with cancer and COVID-19 and identify potential prognostic factors for mortality and severe illness. Methods In t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21d89f8d57a74fe5fc8b244572e6a776
https://doi.org/10.1016/s0140-6736(20)31187-9
https://doi.org/10.1016/s0140-6736(20)31187-9