Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Deborah A. Spina"'
Autor:
Kimberly Rozett, David M. Mauro, Barbara B. Taylor, Aruna Koganti, Eric H. Weyand, Bing-Li Ma, Deborah A. Spina
Publikováno v:
Environmental Science & Technology. 32:3104-3112
The systemic bioavailability of polynuclear aromatic hydrocarbons (PAH) from ingested soils containing manufactured gas plant (MGP) tar was evaluated in mice. Soil and organic extract of each soil were incorporated into a diet and fed to mice for two
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a5ce339c5e8f5e7f76fc1bed44b2ccbf
https://doi.org/10.1021/es980082f
https://doi.org/10.1021/es980082f
Publikováno v:
Chemical Research in Toxicology. 8:772-779
In the rat, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) induces lung tumors independent of the route of administration. To exert its carcinogenic potential, NNK must be metabolically activated. Like most nitrosamines NNK is activated by alph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::890c6032bb21f71026ace9984d893182
https://doi.org/10.1021/tx00047a018
https://doi.org/10.1021/tx00047a018
Autor:
Sharon E. Murphy, Deborah A. Spina
Publikováno v:
Carcinogenesis. 15(12)
The tobacco-specific nitrosamine N'-nitrosonornicotine (NNN) induces esophageal but not liver tumors in the rat. This may in part be due to tissue-specific differences in the activation of this nitrosamine. Therefore, the metabolism of NNN by microso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae180c75ce482a815c500d6bfb8b188f
https://pubmed.ncbi.nlm.nih.gov/8001225
https://pubmed.ncbi.nlm.nih.gov/8001225
Publikováno v:
ACS Symposium Series ISBN: 0841228566
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e4ed7baef3ba4d9ccaa74a25cc72850e
https://doi.org/10.1021/bk-1994-0553.ch018
https://doi.org/10.1021/bk-1994-0553.ch018
Autor:
RICHARD N. LOEPPKY, CHRISTOPHER J. MICHEJDA, Donald C. Havery, Hardy J. Chou, R. A. Scanlan, J. F. Barbour, F. W. Bodyfelt, L. M. Libbey, B. Spiegelhalder, C.-D. Wacker, Yen T. Bao, Jaeyoung Bae, Li Yu, Graziella Shevlin, D. L. H. Williams, Brian C. Challis, Neil Carman, Maria H. R. Fernandes, Benjamin R. Glover, Farida Latif, Pravin Patel, Jaswinder S. Sandhu, Shabaz Shuja, A. R. Tricker, B. Pfundstein, R. Preussmann, B. Pignatelli, C. Malaveille, P. Thuillier, A. Hautefeuille, H. Bartsch, Steven R. Tannenbaum, Snait Tamir, Teresa de Rojas-Walker, John S. Wishnok, Larry K. Keefer, Danae Christodoulou, Tambra M. Dunams, Joseph A. Hrabie, Chris M. Maragos, Joseph E. Saavedra, David A. Wink, J. H. Hotchkiss, R. H. Liu, T. J. Lillard, M. Mochizuki, E. Okochi, K. Shimoda, K. Ito, Chung S. Yang, Theresa J. Smith, Jun-Yan Hong, Shiqi Zhou, G. Eisenbrand, C. Janzowski, Steven R. Koepke, Marilyn B. Kroeger Koepke, Lidia Hernandez, Stephen S. Hecht, Neil Trushin, Steven G. Carmella, Sharon E. Murphy, Deborah A. Spina, Rachel Heiblum, Fung-Lung Chung, Mark M.