Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Deborah A. Lazzarino"'
Autor:
Alison E. Obr, Sushil Kumar, Yun-Juan Chang, Joseph J. Bulatowicz, Betsy J. Barnes, Raymond B. Birge, Deborah A. Lazzarino, Emily Gallagher, Derek LeRoith, Teresa L. Wood
Publikováno v:
Breast Cancer Research, Vol 20, Iss 1, Pp 1-17 (2018)
Abstract Background Early analyses of human breast cancer identified high expression of the insulin-like growth factor type 1 receptor (IGF-1R) correlated with hormone receptor positive breast cancer and associated with a favorable prognosis, whereas
Externí odkaz:
https://doaj.org/article/7527002bf9444f9290465c96b376aa31
Autor:
Derek LeRoith, Teresa L. Wood, Shoshana Yakar, Stefania Santopietro, Wilson Mejia, Naamit Kurshan, Alfredo A. Molinolo, Patricia A. Pennisi, Marco M. Gottardis, Joan M. Carboni, Yvonne Fierz, Deborah A. Lazzarino, Anne Rowzee, Archana Vijayakumar, Danielle E. Lann, Ruslan Novosyadlyy
Epidemiologic studies suggest that type 2 diabetes (T2D) increases breast cancer risk and mortality, but there is limited experimental evidence supporting this association. Moreover, there has not been any definition of a pathophysiological pathway t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94320ed7c90392ec2b424e1de0e0ca83
https://doi.org/10.1158/0008-5472.c.6501216
https://doi.org/10.1158/0008-5472.c.6501216
Autor:
Derek LeRoith, Teresa L. Wood, Shoshana Yakar, Stefania Santopietro, Wilson Mejia, Naamit Kurshan, Alfredo A. Molinolo, Patricia A. Pennisi, Marco M. Gottardis, Joan M. Carboni, Yvonne Fierz, Deborah A. Lazzarino, Anne Rowzee, Archana Vijayakumar, Danielle E. Lann, Ruslan Novosyadlyy
Supplementary Methods from Insulin-Mediated Acceleration of Breast Cancer Development and Progression in a Nonobese Model of Type 2 Diabetes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c12d21fe838380e0ef7c3908feb7790
https://doi.org/10.1158/0008-5472.22385397.v1
https://doi.org/10.1158/0008-5472.22385397.v1
Autor:
Derek LeRoith, Teresa L. Wood, Shoshana Yakar, Stefania Santopietro, Wilson Mejia, Naamit Kurshan, Alfredo A. Molinolo, Patricia A. Pennisi, Marco M. Gottardis, Joan M. Carboni, Yvonne Fierz, Deborah A. Lazzarino, Anne Rowzee, Archana Vijayakumar, Danielle E. Lann, Ruslan Novosyadlyy
Supplementary Figure Legends 1-5 from Insulin-Mediated Acceleration of Breast Cancer Development and Progression in a Nonobese Model of Type 2 Diabetes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17eb74c8bf942359f6decfc42617fb46
https://doi.org/10.1158/0008-5472.22385400.v1
https://doi.org/10.1158/0008-5472.22385400.v1
Autor:
Dhivyaa Alagappan, Deborah A Lazzarino, Ryan J Felling, Murugabaskar Balan, Sergei V Kotenko, Steven W Levison
Publikováno v:
ASN Neuro, Vol 1 (2009)
There is an increase in the numbers of neural precursors in the SVZ (subventricular zone) after moderate ischaemic injuries, but the extent of stem cell expansion and the resultant cell regeneration is modest. Therefore our studies have focused on un
Externí odkaz:
https://doaj.org/article/450f27e586e24d5eb1fda1113e4a630a
Autor:
Joseph J. Bulatowicz, Derek LeRoith, Emily J. Gallagher, Deborah A. Lazzarino, Raymond B. Birge, Yun-Juan Chang, Betsy J. Barnes, Alison E. Obr, Teresa L. Wood, Sushil Kumar
Publikováno v:
Breast Cancer Research : BCR
Breast Cancer Research, Vol 20, Iss 1, Pp 1-17 (2018)
Breast Cancer Research, Vol 20, Iss 1, Pp 1-17 (2018)
Background Early analyses of human breast cancer identified high expression of the insulin-like growth factor type 1 receptor (IGF-1R) correlated with hormone receptor positive breast cancer and associated with a favorable prognosis, whereas low expr
Autor:
Sain Shushanov, Teresa L. Wood, Lauren Rota, Derek LeRoith, Marcus E Shin, Lidia Albanito, Emily J. Gallagher, Corey Goyeneche, Deborah A Lazzarino
Publikováno v:
Cancer Research. 74:5668-5679
Triple-negative breast cancer (TNBC) is an aggressive disease subtype that, unlike other subtypes, lacks an effective targeted therapy. Inhibitors of the insulin-like growth factor receptor (IGF1R) have been considered for use in treating TNBC. Here,
Publikováno v:
Journal of Mammary Gland Biology and Neoplasia
Originally adapted from the neurosphere assay, the nonadherent mammosphere assay has been utilized to assess early progenitor/stem cell frequency in a given population of mammary epithelial cells. This method has also been used to measure the frequen
Autor:
Andrew P. LeBeau, Alan Hochberg, Deborah A. Lazzarino, Robert J. Romanelli, Clifton G. Fulmer, Teresa L. Wood
Publikováno v:
Journal of Biological Chemistry. 282:22513-22524
Previously we demonstrated that insulin-like growth factor-I mediates the sustained phosphorylation of Akt, which is essential for long term survival and protection of glial progenitors from glutamate toxicity. These prosurvival effects correlated wi
Autor:
Richard J. Alexander, Katie Y. Zhang, Elgilda Musi, Lilian Liaw, Maribel de Diego, Seema Shaikh, Shalom Z. Hirschman, Deborah A. Lazzarino
Publikováno v:
Cytokine. 14:234-239
Product R (Reticulose) is a peptide-nucleic acid immunomodulator recently shown to enhance the expression of mRNAs encoding pro-inflammatory cytokines. Interleukin 8 (IL-8) and macrophage chemoattractant protein-1 (MCP-1) are pro-inflammatory chemoki