Zobrazeno 1 - 10
of 221
pro vyhledávání: '"Deborah A. Lawlor"'
Autor:
Ahmed Elhakeem, Monika Frysz, Ana Goncalves Soares, Joshua A. Bell, Tim J. Cole, Jon Heron, Laura D. Howe, Sylvain Sebert, Kate Tilling, Nicholas J. Timpson, Deborah A. Lawlor
Publikováno v:
Communications Medicine, Vol 4, Iss 1, Pp 1-11 (2024)
Abstract Background Pubertal timing is heritable, varies between individuals, and has implications for life-course health. There are many different indicators of pubertal timing, and how they relate to each other is unclear. Our aim was to quantitati
Externí odkaz:
https://doaj.org/article/94f5579c3a254120a61ae036b680badd
Autor:
Junxi Liu, Rebecca C. Richmond, Emma L. Anderson, Jack Bowden, Ciarrah-Jane S. Barry, Hassan S. Dashti, Iyas S. Daghlas, Jacqueline M. Lane, Simon D. Kyle, Céline Vetter, Claire L. Morrison, Samuel E. Jones, Andrew R. Wood, Timothy M. Frayling, Alison K. Wright, Matthew J. Carr, Simon G. Anderson, Richard A. Emsley, David W. Ray, Michael N. Weedon, Richa Saxena, Martin K. Rutter, Deborah A. Lawlor
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Self-reported shorter/longer sleep duration, insomnia, and evening preference are associated with hyperglycaemia in observational analyses, with similar observations in small studies using accelerometer-derived sleep traits. Mendelian random
Externí odkaz:
https://doaj.org/article/7570bd5e2c7049fda1219de8ef4b9840
Autor:
Ahmed Elhakeem, Gemma L. Clayton, Ana Goncalves Soares, Kurt Taylor, Léa Maitre, Gillian Santorelli, John Wright, Deborah A. Lawlor, Martine Vrijheid
Publikováno v:
BMC Pregnancy and Childbirth, Vol 24, Iss 1, Pp 1-15 (2024)
Abstract Background Lower socioeconomic position (SEP) associates with adverse pregnancy and perinatal outcomes and with less favourable metabolic profile in nonpregnant adults. Socioeconomic differences in pregnancy metabolic profile are unknown. We
Externí odkaz:
https://doaj.org/article/2d44ea3d85e146d1a510ea7740f1824d
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract We explore the relation between age at menarche, parity and age at natural menopause with 249 metabolic traits in over 65,000 UK Biobank women using multivariable regression, Mendelian randomization and negative control (parity only). Older
Externí odkaz:
https://doaj.org/article/ed9e48554ac646949838851d3c4938e0
Autor:
Kate Birnie, Janet Catov, Emma L. Anderson, Winok Lapidaire, Fanny Kilpi, Deborah A. Lawlor, Abigail Fraser
Publikováno v:
The Journal of Clinical Hypertension, Vol 26, Iss 2, Pp 166-176 (2024)
Abstract Hypertensive disorders of pregnancy (HDP) are associated with an increased risk of cardiovascular disorders, with recent evidence linking pre‐eclampsia with vascular dementia. We examined associations of HDP with cognitive performance meas
Externí odkaz:
https://doaj.org/article/e114cabbb77d4c7dbbe1570fb15940c5
Autor:
Álvaro Hernáez, Karoline H. Skåra, Christian M. Page, Vera R. Mitter, Marta H. Hernández, Per Magnus, Pål R. Njølstad, Ole A. Andreassen, Elizabeth C. Corfield, Alexandra Havdahl, Øyvind Næss, Ben Brumpton, Bjørn Olav Åsvold, Deborah A. Lawlor, Abigail Fraser, Maria Christine Magnus
Publikováno v:
BMC Medicine, Vol 22, Iss 1, Pp 1-11 (2024)
Abstract Background Adverse pregnancy outcomes (APO) may unmask or exacerbate a woman’s underlying risk for coronary heart disease (CHD). We estimated associations of maternal and paternal genetically predicted liability for CHD with lifelong risk
Externí odkaz:
https://doaj.org/article/794027a6b3ed4e33afb73cb07b50b36f
Autor:
Maria Carolina Borges, Gemma L. Clayton, Rachel M. Freathy, Janine F. Felix, Alba Fernández-Sanlés, Ana Gonçalves Soares, Fanny Kilpi, Qian Yang, Rosemary R. C. McEachan, Rebecca C. Richmond, Xueping Liu, Line Skotte, Amaia Irizar, Andrew T. Hattersley, Barbara Bodinier, Denise M. Scholtens, Ellen A. Nohr, Tom A. Bond, M. Geoffrey Hayes, Jane West, Jessica Tyrrell, John Wright, Luigi Bouchard, Mario Murcia, Mariona Bustamante, Marc Chadeau-Hyam, Marjo-Riitta Jarvelin, Martine Vrijheid, Patrice Perron, Per Magnus, Romy Gaillard, Vincent W. V. Jaddoe, William L. Lowe, Bjarke Feenstra, Marie-France Hivert, Thorkild I. A. Sørensen, Siri E. Håberg, Sylvain Serbert, Maria Magnus, Deborah A. Lawlor
Publikováno v:
BMC Medicine, Vol 22, Iss 1, Pp 1-14 (2024)
Abstract Background Higher maternal pre-pregnancy body mass index (BMI) is associated with adverse pregnancy and perinatal outcomes. However, whether these associations are causal remains unclear. Methods We explored the relation of maternal pre-/ear
Externí odkaz:
https://doaj.org/article/0a4789dc4d5f4384bda3a38300dc1bb0
Autor:
Rebecca C. Richmond, Laurence J. Howe, Karl Heilbron, Samuel Jones, Junxi Liu, andMe Research Team, Xin Wang, Michael N. Weedon, Martin K. Rutter, Deborah A. Lawlor, George Davey Smith, Céline Vetter
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-14 (2023)
Abstract Spouses may affect each other’s sleeping behaviour. In 47,420 spouse-pairs from the UK Biobank, we found a weak positive phenotypic correlation between spouses for self-reported sleep duration (r = 0.11; 95% CI = 0.10, 0.12) and a weak inv
Externí odkaz:
https://doaj.org/article/0d6afd73158a41388c6fdaaca120cd03
Autor:
Caroline Brito Nunes, Maria Carolina Borges, Rachel M. Freathy, Deborah A. Lawlor, Elisabeth Qvigstad, David M. Evans, Gunn-Helen Moen
Publikováno v:
Metabolites, Vol 14, Iss 9, p 508 (2024)
Background/Objectives: During pregnancy, physiological changes in maternal circulating glucose levels and its metabolism are essential to meet maternal and fetal energy demands. Major changes in glucose metabolism occur throughout pregnancy and consi
Externí odkaz:
https://doaj.org/article/8f33c21fdc2e4c388603a8c2c25a90c6
Autor:
Andrew Boyd, Deborah A. Lawlor, Kate Northstone, Jean Golding, Karen Birmingham, Yasmin Iles-Caven, Abigail Fraser, Steven Gregory
Publikováno v:
Wellcome Open Research, Vol 6 (2024)
Background When the Avon Longitudinal Study of Parents and Children (ALSPAC) was planned, it was assumed that the clinical obstetric data would be easily accessible from the newly developed National Health Service computerised ‘STORK’ system. Pil
Externí odkaz:
https://doaj.org/article/51effd1a8ddc4c4485caffbfd68d7a0b