Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Deborah A Sanders"'
Autor:
Maria Vias, Lena Morrill Gavarró, Carolin M Sauer, Deborah A Sanders, Anna M Piskorz, Dominique-Laurent Couturier, Stéphane Ballereau, Bárbara Hernando, Michael P Schneider, James Hall, Filipe Correia-Martins, Florian Markowetz, Geoff Macintyre, James D Brenton
Publikováno v:
eLife, Vol 12 (2023)
High-grade serous ovarian carcinoma (HGSOC) is the most genomically complex cancer, characterized by ubiquitous TP53 mutation, profound chromosomal instability, and heterogeneity. The mutational processes driving chromosomal instability in HGSOC can
Externí odkaz:
https://doaj.org/article/850eb78c25664e2982c8900a7a2a9606
Autor:
Lena Morrill Gavarró, Maria Vias, Carolin M Sauer, Deborah A Sanders, Anna M Piskorz, Dominique-Laurent Couturier, Stéphane Ballereau, Bárbara Hernando, Michael P Schneider, James Hall, Filipe Correia-Martins, Florian Markowetz, Geoff Macintyre, James D Brenton
Publikováno v:
eLife. 12
High-grade serous ovarian carcinoma (HGSOC) is the most genomically complex cancer, characterized by ubiquitous TP53 mutation, profound chromosomal instability, and heterogeneity. The mutational processes driving chromosomal instability in HGSOC can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b4af16f2a03ca7ef85212a031a75733
https://doi.org/10.7554/elife.83867
https://doi.org/10.7554/elife.83867
Autor:
Lena Morrill Gavarró, Maria Vias, Carolin M Sauer, Deborah A Sanders, Anna M Piskorz, Dominique-Laurent Couturier, Stéphane Ballereau, Bárbara Hernando, Michael P Schneider, James Hall, Filipe Correia-Martins, Florian Markowetz, Geoff Macintyre, James D Brenton
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0846d26347963f0ae3a17092db45b516
https://doi.org/10.7554/elife.83867.sa2
https://doi.org/10.7554/elife.83867.sa2
Autor:
Thomas B.K. Watkins, James A. Hall, Charles Swanton, Carlos Caldas, Carolin M. Sauer, Barry R. Davies, Helen Bolton, Peter Baldwin, Sabina Cosulich, Maria Vias, Matthew D. Eldridge, Karen Hosking, Dominique-Laurent Couturier, James D. Brenton, Mercedes Jimenez-Linan, Robin Crawford, Krishnayan Haldar, Larissa S. Carnevalli, Ines de Santiago, Filipe C. Martins, Kevin Litchfield, Gabriel Funingana, Bristi Basu, Gerard I. Evan, John Latimer, Anna M. Piskorz, Iain A. McNeish, Anumithra Amirthanayagam, Deborah A. Sanders, Mihaela Angelova, Sohrab P. Shah, Nicholas McGranahan
The genomic complexity and heterogeneity of high-grade serous ovarian cancer (HGSOC) has hampered the realisation of successful therapies and effective personalised treatment is an unmet clinical need. Here we show that primary HGSOC spheroid models
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6831132d62db72d2fba321990edc2300
https://doi.org/10.1101/2020.10.04.325365
https://doi.org/10.1101/2020.10.04.325365
Autor:
James D. Brenton, Maria Vias, James A. Hall, D-L Couturier, Karen Hosking, Robin Crawford, Deborah A. Sanders, I. de Santiago, Filipe C. Martins, Mercedes Jimenez-Linan, Anna M. Piskorz
Publikováno v:
Annals of Oncology. 30:vii10-vii11
Background The extreme genomic heterogeneity of high-grade serous ovarian carcinoma (HGSOC) is a major barrier to precision medicine approaches. We have developed mutational signature analysis from shallow whole genome sequencing (sWGS) for molecular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd0469d68ea0d6ea88e38030b7235946
https://doi.org/10.1093/annonc/mdz413.038
https://doi.org/10.1093/annonc/mdz413.038
Publikováno v:
Cardiovascular Research
AIMS: Pre-eclampsia affects 5-7% of pregnancies, and is a major cause of maternal and foetal death. Elevated serum levels of placentally derived splice variants of the vascular endothelial growth factor (VEGF) receptor, soluble fms-like tyrosine kina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84131f6a43f74e539dcd041c64baa90a
http://europepmc.org/articles/PMC3028975
http://europepmc.org/articles/PMC3028975
Autor:
Shankar Balasubramanian, Jonathan A. Fletcher, Stephen Neidle, Sven Sewitz, Mekala Gunaratnam, Mallesham Bejugam, Deborah A. Sanders, Sebastian Müller
Publikováno v:
ACS Medicinal Chemistry Letters. 1:306-310
Herein, we demonstrate the design, synthesis, biophysical properties, and preliminary biological evaluation of 6-substituted indenoisoquinolines as a new class of G-quadruplex stabilizing small molecule ligands. We have synthesized 6-substituted inde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8dc50db5d37883aedc41afac879c908
https://doi.org/10.1021/ml100062z
https://doi.org/10.1021/ml100062z
Autor:
Alexander J. Lazar, David R. Kelly, Victor G. Prieto, Deborah Y. Sanders, Marcelo G. Horenstein, Anne H. Bussian, Henry G. Skelton, Kathleen J. Smith, Terry L. Barrett, A. Hafeez Diwan
Publikováno v:
Journal of Cutaneous Pathology. 35:647-650
According to most authors, dermatofibrosarcoma protuberans (DFSP) and giant cell fibroblastoma (GCF) represent the adult and juvenile forms, respectively, of the same disease entity, as evidenced by similar morphology, an identical chromosomal transl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dac6fa1dbec96597f32ae38e7303469
https://doi.org/10.1111/j.1600-0560.2007.00872.x
https://doi.org/10.1111/j.1600-0560.2007.00872.x
Publikováno v:
British Journal of Dermatology. 131:166-176
Summary We have previously developed methods for the isolation and maintenance of human sebaceous glands and hair follicles. However, in long-term culture the maintenance of both is suboptimal. This may be due to a lack of stem cells, which are thoug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90585c0dfbc72e213fc571559b02b2ca
https://doi.org/10.1111/j.1365-2133.1994.tb08487.x
https://doi.org/10.1111/j.1365-2133.1994.tb08487.x
Autor:
Deborah L. Sanders
Publikováno v:
International Journal of Law, Policy and the Family. 17:211-243
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fab6ac23f2daa6c8c0faebc11a489f61
https://doi.org/10.1093/lawfam/17.2.211
https://doi.org/10.1093/lawfam/17.2.211