Výsledky vyhledávání - "Deborah A Rathjen"

Elektronická kniha

Neutrophils, The: New Outlook For Old Cells

Autor: Dmitry I Gabrilovich, Denis English, J Heinecke, Jay Louis Zweier, A Ferrante, Charles S T Hii, Zhi H Huang, Deborah A Rathjen, Marco Cassatella, N F Fanning, H P Redmond, D Bouchier-hayes, Antal Rot, G Virella, Robert L Roberts, David C Dale, S Nelson, R Strauss

This invaluable volume, written by group of internationally established scientists, presents an overview of the most recent findings on the biology of neutrophils. These cells have become a focus of attention in recent years because of their fascinat

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Inhibition of Neutrophil Leukotriene B4 Production by a Novel Synthetic N-3 Polyunsaturated Fatty Acid Analogue, β-Oxa 21:3n-3

Autor: Christopher J. Easton, Deborah Ann Rathjen, Neil Alan Trout, B S Robinson, Antonio Ferrante

Publikováno v: The Journal of Immunology. 171:4773-4779

We recently reported the synthesis and anti-inflammatory properties of a novel long chain polyunsaturated fatty acid (PUFA) with an oxygen atom in the β-position, β-oxa-21:3 n-3 (Z,Z,Z)-(octadeca-9,12,15-trienyloxy) acetic acid). Our data, from stu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::600cc6427cac1e58c2df72ad6890a779
https://doi.org/10.4049/jimmunol.171.9.4773

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Oxidation of oxa and thia fatty acids and related compounds catalysed by 5- and 15-lipoxygenase

Autor: Christopher J. Easton, Michael J. Pitt, Antonio Ferrante, Deborah A. Rathjen, Thomas Alistair Robertson, Alfred Poulos

Publikováno v: Bioorganic & Medicinal Chemistry. 9:317-322

The modified fatty acids, (Z,Z,Z)-(octadeca-6,9,12-trienyloxy)acetic acid, (Z,Z,Z)-(octadeca-9,12,15-trienyloxy)acetic acid, (all-Z)-(eicosa-5,8,11,14-tetraenyloxy)acetic acid, (all-Z)-(eicosa-5,8,11,14-tetraenylthio)acetic acid, 3-[(all-Z)-(eicosa-5

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::875adc8ffae78bd56de5b0e46d373c4d
https://doi.org/10.1016/s0968-0896(00)00246-7

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Stimulation of p38 Phosphorylation and Activity by Arachidonic Acid in HeLa Cells, HL60 Promyelocytic Leukemic Cells, and Human Neutrophils

Autor: Maurizio Costabile, Zhi H. Huang, Andrea J. Bilney, Andrew W. Murray, Deborah Ann Rathjen, Antonio Ferrante, Charles S. T. Hii, Channing J. Der

Publikováno v: Journal of Biological Chemistry. 273:19277-19282

Although it is well appreciated that arachidonic acid, a second messenger molecule that is released by ligand-stimulated phospholipase A2, stimulates a wide range of cell types, the mechanisms that mediate the actions of arachidonic acid are still po

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::881955682bf492554a093d5d290179d2
https://doi.org/10.1074/jbc.273.30.19277

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Synthesis of hydroperoxide and perketal derivatives of polyunsaturated fatty acids as potential antimalarial agents

Autor: Michael J. Pitt, Alfred Poulos, Christopher J. Easton, L M Kumaratilake, Deborah Ann Rathjen, A. Ferrante, Thomas Robertson

Publikováno v: Tetrahedron Letters. 39:4401-4404

Hydroperoxide derivatives of beta-oxa-substituted polyunsaturated fatty acids were prepared by 15-lipoxygenase catalysed oxidation and perketal derivatives of fatty acid hydroperoxides were synthesized. The perketals are more stable than their parent

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::842cea95c339de973b04003413a05d1a
https://doi.org/10.1016/s0040-4039(98)00747-3

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A Tumor Necrosis Factor Mimetic Peptide Activates a Murine Macrophage Cell Line To Inhibit Mycobacterial Growth in a Nitric Oxide-Dependent Fashion

Autor: Helen Briscoe, Warwick J. Britton, N. Meadows, D. R. Roach, Deborah Ann Rathjen

Publikováno v: Infection and Immunity. 66:2122-2127

The control of mycobacterial infections depends on the cytokine-mediated activation of mononuclear phagocytes to inhibit the growth of intracellular mycobacteria. Optimal activation requires the presence of T-cell-derived gamma interferon (IFN-γ) an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65b05629c4c1c0418840ca510fd8af16
https://doi.org/10.1128/iai.66.5.2122-2127.1998

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Inhibitory effects of arachidonic acid (20:4,n-6) and its monohydroperoxy- and hydroxy-metabolites on procoagulant activity in endothelial cells

Autor: Antonio Ferrante, Alf Poulos, Lisa G. Smithers, B S Robinson, E. J. Bates, Deborah A. Rathjen

Publikováno v: Atherosclerosis. 116:125-133

The procoagulant response of endothelium to pathophysiological agents such as tumour necrosis factor α (TNFα) and phorbol myristate acetate (PMA) alters the expression of proteins such as tissue factor. The modulation of such procoagulant activity

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d24cbd3b8f25a7bd47b5868c565e632
https://doi.org/10.1016/0021-9150(95)05538-8

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Activation of Mitogen-activated Protein Kinase by Arachidonic Acid in Rat Liver Epithelial WB Cells by a Protein Kinase C-dependent Mechanism

Autor: Zhi H. Huang, Perry J. Hartfield, Alf Poulos, Yasmin S. Edwards, Deborah Ann Rathjen, Andrew W. Murray, Charles S. T. Hii, A. Ferrante

Publikováno v: Journal of Biological Chemistry. 270:4201-4204

Arachidonic acid (20:4(n-6)), which is released by cells responding to a wide range of stimuli, may play an important role in intracellular signaling. We now report that incubation of WB cells with 20:4(n-6) resulted in the appearance of several tyro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1015853972675faf0f9ed54834678e5a
https://doi.org/10.1074/jbc.270.9.4201

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