Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Deborah A Bradley"'
Autor:
Kuei C. Lee, Deborah A. Bradley, Maha Hussain, Charles R. Meyer, Thomas L. Chenevert, Jon A. Jacobson, Timothy D. Johnson, Craig J. Galban, Alnawaz Rehemtulla, Kenneth J. Pienta, Brian D. Ross
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 9, Iss 12, Pp 1003-1011 (2007)
Prostate cancer (PCa) is the most commonly diagnosed cancer in American men with a subset inevitably presenting with metastatic disease to the bone. A wellrecognized limitation in evaluating new treatments for metastatic PCa is the inability to use i
Externí odkaz:
https://doaj.org/article/75752c7f186f41509c68e61f796d49e5
Publikováno v:
Geological Society of America Abstracts with Programs.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b17c3a6525808be01551adcbc241d465
https://doi.org/10.1130/abs/2016am-283983
https://doi.org/10.1130/abs/2016am-283983
Autor:
Merrill J. Egorin, Stephanie Daignault, Bryan J. Schneider, Deborah A. Bradley, Rodney L. Dunn, Gregory P. Kalemkerian, David Smith, Maha Hussain
Publikováno v:
Investigational New Drugs. 30:249-257
Introduction Vorinostat is an inhibitor of histone deacetylase 6, which acetylates tubulin and stabilizes microtubules. Since taxanes also stabilize microtubules, we hypothesized that the administration of vorinostat followed by docetaxel should resu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::864aa68f824d8ed3e8cd828b7a1adb70
https://doi.org/10.1007/s10637-010-9503-6
https://doi.org/10.1007/s10637-010-9503-6
Autor:
Deborah A, Bradley, Stephanie, Daignault, Charles J, Ryan, Robert S, Dipaola, Kathleen A, Cooney, David C, Smith, Eric, Small, Paul, Mathew, Mitchell E, Gross, Mark N, Stein, Alice, Chen, Kenneth J, Pienta, June, Escara-Wilke, Gerald, Doyle, Mahmoud, Al-Hawary, Evan T, Keller, Maha, Hussain
Publikováno v:
Investigational New Drugs. 29:1432-1440
Background Integrins are involved in prostate cancer metastasis by regulating cell adhesion, migration, invasion, motility, angiogenesis and bone metabolism. We evaluated the efficacy of two dose levels of cilengitide in patients (pts) with castrate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::891b7d63f19cdfc9ea9069af2ecf73a5
https://doi.org/10.1007/s10637-010-9420-8
https://doi.org/10.1007/s10637-010-9420-8
Autor:
David Smith, Glenn Liu, Maha Hussain, Walter M. Stadler, Dana E. Rathkopf, Deborah A. Bradley, Howard I. Scher, Roberto Pili, Rodney L. Dunn, James A. Zwiebel
Publikováno v:
Cancer. 115:5541-5549
BACKGROUND: This phase 2 trial was designed to evaluate the efficacy of vorinostat in chemotherapy-pretreated patients with metastatic castration-resistant prostate cancer. METHODS: Patients with disease progression on 1 prior chemotherapy, a prostat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78af4c7a09943d4bae8b4c50a890eb4e
https://doi.org/10.1002/cncr.24597
https://doi.org/10.1002/cncr.24597
Publikováno v:
Targeted Oncology. 3:31-39
The results of two phase III trials demonstrating a significant prolongation of survival with docetaxel-based chemotherapy has fueled interest in expanding therapeutic development in prostate cancer. This coupled with improved understanding of the me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::29781e4db39f58471d6dfe2afcc9addc
https://doi.org/10.1007/s11523-007-0067-0
https://doi.org/10.1007/s11523-007-0067-0
Autor:
Scott A. Tomlins, Arul M. Chinnaiyan, Deborah A. Bradley, Robert D. Loberg, Kenneth J. Pienta
Publikováno v:
CA: A Cancer Journal for Clinicians. 57:225-241
The last decade has seen an explosion in knowledge of the molecular basis and treatment of cancer. The molecular events that define the lethal phenotype of various cancers--the genetic and cellular alterations that lead to a cancer with a poor or inc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::018de741570b880a8ffbf407890311f1
https://doi.org/10.3322/canjclin.57.4.225
https://doi.org/10.3322/canjclin.57.4.225
Autor:
Deborah A. Bradley, Bruce G. Redman
Publikováno v:
Cancer. 110:2366-2369
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::36f1f669e03aa6eebd256b643b31f13f
https://doi.org/10.1002/cncr.23053
https://doi.org/10.1002/cncr.23053
Publikováno v:
Chest. 128:1062-1067
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d1d39b16e53b563803e04fdba3134d3f
https://doi.org/10.1016/s0012-3692(15)50471-6
https://doi.org/10.1016/s0012-3692(15)50471-6
Publikováno v:
Breast Cancer Research and Treatment. 90:65-70
Hormone responsive breast cancer is usually determined by the presence of estrogen receptors (ER) or progesterone receptors (PR) on primary invasive breast cancers. Adjuvant and metastatic hormone therapy are recommended based on primary ER and PR de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21d89e1e6ea11c06e465b7e3c7f0447a
https://doi.org/10.1007/s10549-004-2756-z
https://doi.org/10.1007/s10549-004-2756-z