Zobrazeno 1 - 10
of 110
pro vyhledávání: '"Deborah McMahon"'
Autor:
Jingxian Chen, Kehmia Titanji, Anandi N. Sheth, Rajesh Gandhi, Deborah McMahon, Ighovwerha Ofotokun, M. Neale Weitzmann, Kristina De Paris, Julie B. Dumond
Publikováno v:
Immunity & Ageing, Vol 19, Iss 1, Pp 1-13 (2022)
Abstract Older age could be a risk factor for suboptimal CD4+ T-cell recovery in HIV-infected patients despite successful viral suppression. However, evaluation of this effect could be confounded by age-related immune processes such as decreased thym
Externí odkaz:
https://doaj.org/article/3847fcbebe164f21838999e9e1d5edd8
Autor:
Ioannis Konstantinidis, Shulin Qin, Meghan Fitzpatrick, Cathy Kessinger, Heather Gentry, Deborah McMahon, R. Dawn Weinman, Phyllis Tien, Laurence Huang, Meredith McCormack, Igor Barjaktarevic, Divya Reddy, Robert Foronjy, Deepa Lazarous, Mardge H. Cohen, Heather McKay, Adaora A. Adimora, Caitlin Moran, Margaret A. Fischl, Jodie Dionne-Odom, Valentina Stosor, M. Bradley Drummond, Sushma K. Cribbs, Ken Kunisaki, Charles Rinaldo, Alison Morris, S. Mehdi Nouraie
Publikováno v:
Annals of the American Thoracic Society. 19:2013-2020
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::592ababf3cbcead132b5ec41cf5b4bff
https://doi.org/10.1513/annalsats.202204-332oc
https://doi.org/10.1513/annalsats.202204-332oc
Autor:
Eva M. Stevenson, Adam R. Ward, Thomas R. Dilling, John K. Bui, John Mellors, Rajesh Gandhi, Deborah McMahon, Joseph Eron, Ronald Bosch, Christina Lalama, Joshua Cyktor, Brad Jones
Publikováno v:
Journal of Virus Eradication, Vol 5, Iss , Pp 32- (2019)
Externí odkaz:
https://doaj.org/article/3c238e6e2bb54924bac5f257d41ee792
Autor:
Tom E Robertson, Mehdi Nouraie, Shulin Qin, Kristina A Crothers, Cathy J Kessinger, Deborah McMahon, Divay Chandra, Lawrence A Kingsley, Ruth M Greenblatt, Laurence Huang, Meghan E Fitzpatrick, Alison Morris
Publikováno v:
PLoS ONE, Vol 14, Iss 4, p e0212975 (2019)
BackgroundAmbulatory function predicts morbidity and mortality and may be influenced by cardiopulmonary dysfunction. Persons living with HIV (PLWH) suffer from a high prevalence of cardiac and pulmonary comorbidities that may contribute to higher ris
Externí odkaz:
https://doaj.org/article/c4c1d2b115fb4c12a0c4948d18d840fd
Autor:
Shulin Qin, Emily Clausen, Seyed Mehdi Nouraie, Lawrence Kingsley, Deborah McMahon, Eric Kleerup, Laurence Huang, Elodie Ghedin, Ruth M Greenblatt, Alison Morris
Publikováno v:
PLoS ONE, Vol 13, Iss 10, p e0205065 (2018)
Studies demonstrate that Tropheryma whipplei (T. whipplei) is present in the lungs of healthy individuals without acute respiratory symptoms or acute respiratory infection and is more common in the lungs of HIV-infected individuals and in smokers. Th
Externí odkaz:
https://doaj.org/article/733c8947b4a34da8a729ce06783d8fb2
Autor:
Mary Ann Checkley, Benjamin G. Luttge, Curtis Dobrowolski, David N. Wald, Deborah McMahon, Ghady Haidar, Michele D. Sobolewski, P. Nathan Enick, Joshua Cyktor, John W. Mellors, Jonathan Karn
Treatment with latency-reversing agents (LRAs) alone has been ineffective in reducing HIV-1 reservoirs in persons with HIV-1 (PWH) on antiretroviral therapy (ART), due to inefficiencies in reservoir reactivation and adaptive immune responses. However
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cfe83ac9c1d4981b9c3f9a34df02c8a6
https://doi.org/10.1101/2022.09.05.506592
https://doi.org/10.1101/2022.09.05.506592
Autor:
Curtis Dobrowolski, Michael F. Para, Jonathan Karn, Joshua C. Cyktor, Edward P. Acosta, Ronald T. Mitsuyasu, Joseph Hesselgesser, Joan Dragavon, Evgenia Aga, Rajesh T. Gandhi, Bernard J.C. Macatangay, John W. Mellors, Deborah McMahon, Catherine Godfrey, Lu Zheng
Publikováno v:
J Infect Dis
Background Romidepsin (RMD) is a histone deacetylase inhibitor reported to reverse HIV-1 latency. We sought to identify doses of RMD that were safe and induced HIV-1 expression. Methods Enrollees had HIV-1 RNA Results In the single-dose cohorts 1–3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a234f1b2b2d2524ea5ab6ea78e5f3f29
https://doi.org/10.1093/infdis/jiaa777
https://doi.org/10.1093/infdis/jiaa777
Publikováno v:
J Pharmacol Exp Ther
Dolutegravir (DTG) is a potent integrase inhibitor of human immunodeficiency virus. Because DTG is a substrate of the efflux transporter ABCG2 and ABCG2 is highly polymorphic, we asked whether dose adjustment of DTG is needed for ABCG2-deficient indi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::674d1d9f808c055ef70831ba7d326127
https://doi.org/10.1124/jpet.119.264424
https://doi.org/10.1124/jpet.119.264424
Autor:
Szu-Han Huang, Adam R. Ward, Joshua C. Cyktor, R. Brad Jones, Ronald J. Bosch, Rajesh T. Gandhi, Sheila M. Keating, John W. Mellors, Eva M. Stevenson, Allison S. Thomas, Joseph J. Eron, Bernard J.C. Macatangay, Deborah McMahon
BackgroundPeople with HIV (PWH) have persistently elevated levels of inflammation and immune activation despite suppressive antiretroviral therapy (ART), with specific biomarkers showing associations with non-AIDS-defining morbidities and mortality.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0023700796b507e9f6cb6e7e94adc04f
https://doi.org/10.1101/2021.11.08.21266096
https://doi.org/10.1101/2021.11.08.21266096
Autor:
Joseph M. Pilewski, Mounzer Agha, James D. Luketich, Amy Lukanski, Derek C. Angus, Robert L. Ferris, Fernanda P. Silveira, Tami Minnier, Scott D. Rothenberger, Cynthia Klamar-Blain, Rachel Troyan, Deborah McMahon, John F. McDyer, P. Nathan Enick, Kelsey Linstrum, Paula L Kip, Alan Wells, Amy Heaps, Bhanu Pappu, Ghady Haidar, Matthew R. Morrell, Michelle Sobolewksi, Abhinav Humar, Mary E. Keebler, Andrew Bilderback, John W. Mellors, Jeffrey Dueker, Stanley M. Marks, Marc Schwartz, Kevin Collins, Urvi M. Parikh, Melissa Crandall
ObjectivesImmunocompromised patients were excluded from COVID-19 vaccine clinical trials. The objectives of the study were to measure antibody responses, levels, and neutralization capability after COVID-19 vaccination among immunocompromised patient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::59d0f908fb263e2b6c09d066d28b7a23
https://doi.org/10.1101/2021.06.28.21259576
https://doi.org/10.1101/2021.06.28.21259576