Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Debora Sesia"'
Autor:
Ludovic Wesolowski, Jianfeng Ge, Leticia Castillon, Debora Sesia, Anna Dyas, Shoko Hirosue, Veronica Caraffini, Anne Y. Warren, Paulo Rodrigues, Giovanni Ciriello, Saroor A. Patel, Sakari Vanharanta
Publikováno v:
iScience, Vol 26, Iss 8, Pp 107360- (2023)
Summary: Lineage switching can induce therapy resistance in cancer. Yet, how lineage fidelity is maintained and how it can be lost remain poorly understood. Here, we have used CRISPR-Cas9-based genetic screening to demonstrate that loss of SMARCB1, a
Externí odkaz:
https://doaj.org/article/629e571c05cc491594e2cb0fca3f5f9e
Autor:
Caterina Peraldo-Neia, Paola Ostano, Giovanna Chiorino, Ilaria Gregnanin, Francesca Guana, Antonella Farsetti, Maurizia Mello-Grand, Elena Jachetti, Debora Sesia
Publikováno v:
International Journal of Molecular Sciences
Volume 21
Issue 3
International Journal of Molecular Sciences, Vol 21, Iss 3, p 1078 (2020)
International journal of molecular sciences (Online) 21 (2020). doi:10.3390/ijms21031078
info:cnr-pdr/source/autori:Ostano, Paola; Mello-Grand, Maurizia; Sesia, Debora; Gregnanin, Ilaria; Peraldo-Neia, Caterina; Guana, Francesca; Jachetti, Elena; Farsetti, Antonella; Chiorino, Giovanna/titolo:Gene Expression Signature Predictive of Neuroendocrine Transformation in Prostate Adenocarcinoma/doi:10.3390%2Fijms21031078/rivista:International journal of molecular sciences (Online)/anno:2020/pagina_da:/pagina_a:/intervallo_pagine:/volume:21
Volume 21
Issue 3
International Journal of Molecular Sciences, Vol 21, Iss 3, p 1078 (2020)
International journal of molecular sciences (Online) 21 (2020). doi:10.3390/ijms21031078
info:cnr-pdr/source/autori:Ostano, Paola; Mello-Grand, Maurizia; Sesia, Debora; Gregnanin, Ilaria; Peraldo-Neia, Caterina; Guana, Francesca; Jachetti, Elena; Farsetti, Antonella; Chiorino, Giovanna/titolo:Gene Expression Signature Predictive of Neuroendocrine Transformation in Prostate Adenocarcinoma/doi:10.3390%2Fijms21031078/rivista:International journal of molecular sciences (Online)/anno:2020/pagina_da:/pagina_a:/intervallo_pagine:/volume:21
Neuroendocrine prostate cancer (NEPC) can arise de novo, but much more commonly occurs as a consequence of a selective pressure from androgen deprivation therapy or androgen receptor antagonists used for prostate cancer (PCa) treatment. The process i