Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Debora Lim"'
Autor:
Stacey M. Leventhal, Debora Lim, Tajia L. Green, Anna E. Cantrell, Kiho Cho, David G. Greenhalgh
Publikováno v:
BMC Genetics, Vol 20, Iss 1, Pp 1-15 (2019)
Abstract Background Glucocorticoids are commonly used in the clinical setting for their potent anti-inflammatory effects; however, significant variations in response to treatment have been demonstrated. Although the underlying mechanisms have yet to
Externí odkaz:
https://doaj.org/article/32c7ccfa85554ed8bd980329925986b6
Publikováno v:
Biochemistry and Biophysics Reports, Vol 9, Iss C, Pp 140-145 (2017)
Glucocorticoids are one of the most widely used therapeutics in the treatment of a variety of inflammatory disorders. However, it is known that there are variable patient responses to glucocorticoid treatment; there are responders and non-responders,
Externí odkaz:
https://doaj.org/article/3a3431d383fe4a31b2dd7f744738eff5
Publikováno v:
International Journal of Genomics, Vol 2017 (2017)
Transposable repetitive elements, named the “TREome,” represent ~40% of the mouse genome. We postulate that the germ line genome undergoes temporal and spatial diversification into somatic genomes in conjunction with the TREome activity. C57BL/6J
Externí odkaz:
https://doaj.org/article/7bd1656cf48a4079804f0539754449e1
Publikováno v:
Shock. 58:393-399
It is well known that bacterial components (pathogen-associated molecular patterns [PAMPs]) induce a proinflammatory response through pattern recognition receptor signaling. What is not known, however, is how the inflammatory response is downregulate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1397ead8f5d4bffa7322c5ae13c51e2a
https://doi.org/10.1097/shk.0000000000002004
https://doi.org/10.1097/shk.0000000000002004
Publikováno v:
Revista Naval de Odontologia On Line, Vol 51, Iss 2, Pp 25-32 (2024)
Osteoma is an unusual benign tumor of bone origin characterized by proliferation of compact or medullary bone. It is most common in adults between the third and fifth decades of life, with no gender predilection and can be categorized as central, per
Externí odkaz:
https://doaj.org/article/8c108128badb4a729c6d1884b50d8fcb
Publikováno v:
Shock. 56:318-324
A potential cause of the variable response to injury and sepsis is the variability of a patient's human glucocorticoid receptor (hGR) profile. To identify hGR variants, blood samples were collected on admission and biweekly thereafter from hospitaliz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a83c6a655ca3ace4ce5c4023a8531b43
https://doi.org/10.1097/shk.0000000000001729
https://doi.org/10.1097/shk.0000000000001729
Publikováno v:
Biochemistry and Biophysics Reports, Vol 9, Iss C, Pp 140-145 (2017)
Biochemistry and Biophysics Reports
Biochemistry and Biophysics Reports
Glucocorticoids are one of the most widely used therapeutics in the treatment of a variety of inflammatory disorders. However, it is known that there are variable patient responses to glucocorticoid treatment; there are responders and non-responders,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32faa2c58a2b8656402da86066338d20
Publikováno v:
Shock. 47:148-157
We previously identified a truncated human glucocorticoid receptor (hGR) isoform of 118 amino acids, hGR-S1(-349A), that despite lacking the major functional domains, was more hyperactive after glucocorticoid treatment than the full-length receptor.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3fde8eb757d46d7f22f9477f9da3fb2
https://doi.org/10.1097/shk.0000000000000750
https://doi.org/10.1097/shk.0000000000000750
Autor:
Kiho Cho, David G. Greenhalgh, Anna E. Cantrell, Tajia L. Green, Stacey M. Leventhal, Debora Lim
Publikováno v:
BMC Genetics
BMC genetics, vol 20, iss 1
BMC Genetics, Vol 20, Iss 1, Pp 1-15 (2019)
BMC genetics, vol 20, iss 1
BMC Genetics, Vol 20, Iss 1, Pp 1-15 (2019)
Background Glucocorticoids are commonly used in the clinical setting for their potent anti-inflammatory effects; however, significant variations in response to treatment have been demonstrated. Although the underlying mechanisms have yet to be fully
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99f3de8da1032b62b049659b0f91277d
http://europepmc.org/articles/PMC6368729
http://europepmc.org/articles/PMC6368729
Publikováno v:
Shock (Augusta, Ga.). 52(6)
Glucocorticoids are widely used in the treatment of numerous inflammatory conditions, including sepsis. Unfortunately, patient response to glucocorticoid therapy can be inconsistent. Variations in the human glucocorticoid receptor (hGR) may contribut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db8dff49b895c4d8ec55979f02f6c441
https://pubmed.ncbi.nlm.nih.gov/30676498
https://pubmed.ncbi.nlm.nih.gov/30676498