Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Debora Lanznaster"'
Autor:
Shanez Haouari, Christian Robert Andres, Debora Lanznaster, Sylviane Marouillat, Céline Brulard, Audrey Dangoumau, Devina Ung, Charlotte Veyrat-Durebex, Frédéric Laumonnier, Hélène Blasco, Philippe Couratier, Philippe Corcia, Patrick Vourc’h
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 2, p 1268 (2023)
The ubiquitin pathway, one of the main actors regulating cell signaling processes and cellular protein homeostasis, is directly involved in the pathophysiology of amyotrophic lateral sclerosis (ALS). We first analyzed, by a next-generation sequencing
Externí odkaz:
https://doaj.org/article/f6efe5e6808a437383f225594e332b3b
Autor:
Hugo Alarcan, Yara Al Ojaimi, Debora Lanznaster, Jean-Michel Escoffre, Philippe Corcia, Patrick Vourc’h, Christian R. Andres, Charlotte Veyrat-Durebex, Hélène Blasco
Publikováno v:
Journal of Personalized Medicine
Journal of Personalized Medicine, MDPI, 2022, 12, pp.1071. ⟨10.3390/jpm12071071⟩
Journal of Personalized Medicine, MDPI, 2022, 12, pp.1071. ⟨10.3390/jpm12071071⟩
International audience; Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disorder that still lacks an efficient therapy. The barriers between the central nervous system (CNS) and the blood represent a major limiting factor to th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32de5f2d815f11f534d87e162481dbf2
https://doi.org/10.3390/jpm12071071
https://doi.org/10.3390/jpm12071071
Autor:
Yara Al Ojaimi, Charlotte Slek, Samira Osman, Hugo Alarcan, Sylviane Marouillat, Philippe Corcia, Patrick Vourc'h, Débora Lanznaster, Hélène Blasco
Publikováno v:
Biochemistry and Biophysics Reports, Vol 38, Iss , Pp 101664- (2024)
Amyotrophic Lateral Sclerosis (ALS) is the most common neurodegenerative disease affecting motor neurons. The pathophysiology of ALS is not well understood but TDP-43 proteinopathy (aggregation and mislocalization) is one of the major phenomena descr
Externí odkaz:
https://doaj.org/article/cda875ecf0304e528815c41960463213
Publikováno v:
Metabolites, Vol 12, Iss 9, p 864 (2022)
Neurodegenerative diseases (NDs), such as Alzheimer’s (AD), Parkinson’s (PD), and amyotrophic lateral sclerosis (ALS), share common pathological mechanisms, including metabolism alterations. However, their specific neuronal cell types affected an
Externí odkaz:
https://doaj.org/article/ffd561e1f1d64cd88008c1b5700afbf9
Autor:
Débora Lanznaster, Clément Bruno, Jérôme Bourgeais, Patrick Emond, Ilyess Zemmoura, Antoine Lefèvre, Pascal Reynier, Sébastien Eymieux, Emmanuelle Blanchard, Patrick Vourc'h, Christian R. Andres, Salah Eddine Bakkouche, Olivier Herault, Luc Favard, Philippe Corcia, Hélène Blasco
Publikováno v:
Biomedicines, Vol 10, Iss 6, p 1307 (2022)
Diverse biomarkers and pathological alterations have been found in muscle of patients with Amyotrophic lateral sclerosis (ALS), but the relation between such alterations and dysfunction in energetic metabolism remains to be investigated. We establish
Externí odkaz:
https://doaj.org/article/0c6ac3b52b754cb082280f2c34753b2d
Autor:
Shanez Haouari, Patrick Vourc’h, Médéric Jeanne, Sylviane Marouillat, Charlotte Veyrat-Durebex, Débora Lanznaster, Frédéric Laumonnier, Philippe Corcia, Hélène Blasco, Christian R. Andres
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 7, p 3882 (2022)
The ubiquitin pathway regulates the function of many proteins and controls cellular protein homeostasis. In recent years, it has attracted great interest in neurodevelopmental and neurodegenerative diseases. Here, we have presented the first review o
Externí odkaz:
https://doaj.org/article/2fda9206c9d648e9b1d101cdd9ef8477
Publikováno v:
Frontiers in Neurology, Vol 11 (2020)
Background: Amyotrophic lateral sclerosis (ALS) is a neurodegenerative condition characterized by the progressive loss of motor neurons. Patients usually die 3–5 years after diagnosis from respiratory failure. Several studies investigated the role
Externí odkaz:
https://doaj.org/article/0be8c7ef31d945b8be1ddecc9dafc6c2
Autor:
Débora Lanznaster, Denis Reis de Assis, Philippe Corcia, Pierre-François Pradat, Hélène Blasco
Publikováno v:
Frontiers in Neurology, Vol 9 (2018)
Biomarkers research in amyotrophic lateral sclerosis (ALS) holds the promise of improving ALS diagnosis, follow-up of patients, and clinical trials outcomes. Metabolomics have a big impact on biomarkers identification. In this mini-review, we provide
Externí odkaz:
https://doaj.org/article/8911e63f16414e439c121ebd5fa2bf68
Autor:
Rudolf Hergesheimer, Débora Lanznaster, Jérôme Bourgeais, Olivier Hérault, Patrick Vourc’h, Christian R. Andres, Philippe Corcia, Hélène Blasco
Publikováno v:
Cells, Vol 9, Iss 10, p 2198 (2020)
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease caused by the progressive death of both upper and lower motor neurons. The disease presents a poor prognosis, and patients usually die 2–5 years after the onset of symptoms. The hal
Externí odkaz:
https://doaj.org/article/03ffca60c85e4dccbae3e4d9179bf004
Autor:
Débora Lanznaster, Rudolf C. Hergesheimer, Salah Eddine Bakkouche, Stephane Beltran, Patrick Vourc’h, Christian R. Andres, Diane Dufour-Rainfray, Philippe Corcia, Hélène Blasco
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 8, p 2911 (2020)
Amyotrophic lateral sclerosis (ALS) is the most common motor neuron disease, but its definitive diagnosis delays around 12 months. Although the research is highly active in the biomarker field, the absence of specific biomarkers for diagnosis contrib
Externí odkaz:
https://doaj.org/article/42c9409711534a9fbb0fafd5b27671d8