Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Debora Fusca"'
Development of a genetically encoded sensor for probing endogenous nociceptin opioid peptide release
Autor:
Xuehan Zhou, Carrie Stine, Patricia Oliveira Prada, Debora Fusca, Kevin Assoumou, Jan Dernic, Musadiq A. Bhat, Ananya S. Achanta, Joseph C. Johnson, Amanda Loren Pasqualini, Sanjana Jadhav, Corinna A. Bauder, Lukas Steuernagel, Luca Ravotto, Dietmar Benke, Bruno Weber, Azra Suko, Richard D. Palmiter, Miriam Stoeber, Peter Kloppenburg, Jens C. Brüning, Michael R. Bruchas, Tommaso Patriarchi
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract Nociceptin/orphanin-FQ (N/OFQ) is a recently appreciated critical opioid peptide with key regulatory functions in several central behavioral processes including motivation, stress, feeding, and sleep. The functional relevance of N/OFQ action
Externí odkaz:
https://doaj.org/article/85f93020cae0443ca2de0481924bf37c
Autor:
Debora Fusca, Peter Kloppenburg
Publikováno v:
eLife, Vol 10 (2021)
Local interneurons (LNs) mediate complex interactions within the antennal lobe, the primary olfactory system of insects, and the functional analog of the vertebrate olfactory bulb. In the cockroach Periplaneta americana, as in other insects, several
Externí odkaz:
https://doaj.org/article/fdff8d6475f84ac3a8c65382d5eef31e
Development of a genetically-encoded sensor for probing endogenous nociceptin opioid peptide release
Autor:
Xuehan Zhou, Carrie Stine, Patricia Oliveira Prada, Debora Fusca, Kevin Assoumou, Jan Dernic, Musadiq A Bhat, Ananya S. Achanta, Joseph C Johnson, Sanjana Jadhav, Corinna A Bader, Lukas Steuernagel, Luca Ravotto, Dietmar Benke, Bruno Weber, Miriam Stoeber, Peter Kloppenburg, Jens Claus Bruening, Michael R Bruchas, Tommaso Patriarchi
Publikováno v:
bioRxiv
Nociceptin/orphanin-FQ (N/OFQ) is a recently appreciated critical opioid peptide with key regulatory functions in several central behavioral processes including motivation, stress, feeding, and sleep. The functional relevance of N/OFQ action in the m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90e2c8ec895fdbf0b6b240626d49745f
https://europepmc.org/articles/PMC10245933/
https://europepmc.org/articles/PMC10245933/
Autor:
Debora Fusca, Peter Kloppenburg
Publikováno v:
eLife, Vol 10 (2021)
Local interneurons (LNs) mediate complex interactions within the antennal lobe, the primary olfactory system of insects, and the functional analog of the vertebrate olfactory bulb. In the cockroachPeriplaneta Americana, as in other insects, several t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9baafd442dea0a3b9dd893514720735
https://doi.org/10.1101/2020.11.26.369686
https://doi.org/10.1101/2020.11.26.369686
Autor:
Peter Kloppenburg, Debora Fusca
Publikováno v:
Cell and Tissue Research
Highly interconnected neural networks perform olfactory signal processing in the central nervous system. In insects, the first synaptic processing of the olfactory input from the antennae occurs in the antennal lobe, the functional equivalent of the
Publikováno v:
ACS Chemical Neuroscience. 9:2089-2096
Single-cell mass spectrometry has become an established technique to study specific molecular properties such as the neuropeptide complement of identified neurons. Here, we describe a strategy to characterize, by MALDI-TOF mass spectrometry, neuroche
Publikováno v:
Journal of Comparative Neurology. 523:1569-1586
In the insect antennal lobe different types of local interneurons mediate complex excitatory and inhibitory interactions between the glomerular pathways to structure the spatiotemporal representation of odors. Mass spectrometric and immunohistochemic
Publikováno v:
Journal of Comparative Neurology. 521:3556-3569
Behavioral and physiological studies have shown that local interneurons are pivotal for processing odor information in the insect antennal lobe. They mediate inhibitory and excitatory interactions between the glomerular pathways and ultimately shape
Autor:
Scott Ayton, Jochen C. Meier, Borislav Dejanovic, Marcus Semtner, Guenter Schwarz, Jose Angel Santamaria-Araujo, Aline Winkelmann, Sita Arjune, Debora Fusca, Abdel A. Belaidi, Ashley I. Bush, Florian Hetsch, Avadh Kumar, Peter Kloppenburg
Publikováno v:
The Journal of clinical investigation. 127(12)
Molybdenum cofactor deficiency (MoCD) is an autosomal recessive inborn error of metabolism characterized by neurodegeneration and death in early childhood. The rapid and progressive neurodegeneration in MoCD presents a major clinical challenge and ma