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pro vyhledávání: '"Debora Cifone"'
Inability of heterologous growth hormone (GH) to regulate GH binding protein in GH-transgenic swine1
Publikováno v:
Journal of Animal Science. 80:1962-1969
Transgenic pigs expressing bovine, ovine, or human growth hormone (GH) structural genes fused to mouse metallothionein-I (mMT-bGH), ovine MT (oMT-oGH), or mouse transferrin (mTf-hGH) promoters were used to study the effects of GH on the regulation of
Publikováno v:
Scopus-Elsevier
Growth hormone (GH) excess is associated with insulin resistance, but the molecular mechanisms of this association are poorly understood. In the current work, we have examined the consequences of exposure to high GH levels on the early steps of the i
Publikováno v:
Journal of Endocrinology. 161:383-392
Growth hormone (GH) excess is associated with secondary hyperinsulinemia, but the molecular mechanism and consequences of this alteration are poorly understood. To address this problem we have examined the levels and phosphorylation state of the insu