Zobrazeno 1 - 10
of 112
pro vyhledávání: '"Debora Aparecida Pires de Campos Zuccari"'
Autor:
Caroline Procópio de Oliveira, Barbara Maria Frigieri, Heidge Fukumasu, Luiz Gustavo de Almeida Chuffa, Adriana Alonso Novais, Debora Aparecida Pires de Campos Zuccari
Publikováno v:
Biomedicines, Vol 11, Iss 10, p 2837 (2023)
(1) Background: Mammary neoplasms in female dogs share many similarities with the same tumor class in humans, rendering these animals a valuable preclinical model for studying novel therapies against breast cancer. The intricate role of extracellular
Externí odkaz:
https://doaj.org/article/283d8aa4fad64916a9dd4e65a9d75c08
Autor:
Adriana Alonso Novais, Guilherme Henrique Tamarindo, Luiz Gustavo de Almeida Chuffa, Debora Aparecida Pires de Campos Zuccari
Publikováno v:
Biomedicines, Vol 11, Iss 10, p 2839 (2023)
Cancer is a complex and heterogeneous disease, influenced by various factors that affect its progression and response to treatment. Although a histopathological diagnosis is crucial for identifying and classifying cancer, it may not accurately predic
Externí odkaz:
https://doaj.org/article/dd3ed55c25ff47098ec07731349d0e5f
Autor:
Russel J. Reiter, Ramaswamy Sharma, Alejandro Romero, Walter Manucha, Dun-Xian Tan, Debora Aparecida Pires de Campos Zuccari, Luiz Gustavo de Almeida Chuffa
Publikováno v:
Antioxidants, Vol 12, Iss 3, p 695 (2023)
Aging has a major detrimental effect on the optimal function of the ovary with changes in this organ preceding the age-related deterioration in other tissues, with the middle-aged shutdown leading to infertility. Reduced fertility and consequent inab
Externí odkaz:
https://doaj.org/article/ffd8337c07144e1c9a8d556ecbb3bba1
Autor:
Rubens Paula Junior, Luiz Gustavo de Almeida Chuffa, Vinicius Augusto Simão, Nathália Martins Sonehara, Roger Chammas, Russel J. Reiter, Debora Aparecida Pires de Campos Zuccari
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 16, p 9105 (2022)
Metabolic dysregulation as a reflection of specific metabolite production and its utilization is a common feature of many human neoplasms. Melatonin, an indoleamine that is highly available during darkness, has a variety of metabolic functions in sol
Externí odkaz:
https://doaj.org/article/2bfbc765a4144eba9d35d9fb7027ee26
Autor:
Maira Smaniotto Cucielo, Roberta Carvalho Cesário, Henrique Spaulonci Silveira, Letícia Barbosa Gaiotte, Sérgio Alexandre Alcantara dos Santos, Debora Aparecida Pires de Campos Zuccari, Fábio Rodrigues Ferreira Seiva, Russel J. Reiter, Luiz Gustavo de Almeida Chuffa
Publikováno v:
Molecules, Vol 27, Iss 14, p 4350 (2022)
Ovarian cancer (OC) is the most lethal gynecologic malignancy, and melatonin has shown various antitumor properties. Herein, we investigated the influence of melatonin therapy on energy metabolism and mitochondrial integrity in SKOV-3 cells and teste
Externí odkaz:
https://doaj.org/article/a4689ee270ec40aca1abcf660c743b96
Autor:
Marina Gobbe Moschetta-Pinheiro, Jucimara Colombo, Bianca Lara Venâncio de Godoy, Julia Ferreira Balan, Bianca Carlos Nascimento, Debora Aparecida Pires de Campos Zuccari
Publikováno v:
Life, Vol 11, Iss 12, p 1427 (2021)
Breast cancer is the most prevalent tumor type among women and female dogs. Tumor malignancy is characterized by the epithelial-to-mesenchymal transition (EMT) which leads to the metastasis formation. The inhibition of angiotensin II type I receptor
Externí odkaz:
https://doaj.org/article/9279a990f24d43bd920d24a7c1d5bfff
Autor:
Russel J Reiter, Ramaswamy Sharma, Sergio Rosales-Corral, Walter Manucha, Luiz Gustavo de Almeida Chuffa, Debora Aparecida Pires de Campos Zuccari
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 22, p 12494 (2021)
Melatonin is synthesized in the pineal gland at night. Since melatonin is produced in the mitochondria of all other cells in a non-circadian manner, the amount synthesized by the pineal gland is less than 5% of the total. Melatonin produced in mitoch
Externí odkaz:
https://doaj.org/article/b8c075225f5941d3bd0da924f60871b4
Autor:
Jucimara Colombo, Marina Gobbe Moschetta-Pinheiro, Adriana Alonso Novais, Bruna Ribeiro Stoppe, Enrico Dumbra Bonini, Francine Moraes Gonçalves, Heidge Fukumasu, Luiz Lehmann Coutinho, Luiz Gustavo de Almeida Chuffa, Debora Aparecida Pires de Campos Zuccari
Publikováno v:
Cancers, Vol 13, Iss 20, p 5233 (2021)
Introduction: Breast cancer (BC) is the malignant neoplasm with the highest mortality rate in women and female dogs are good models to study BC. Objective: We investigated the efficacy of liquid biopsy to detect gene mutations in the diagnosis and fo
Externí odkaz:
https://doaj.org/article/b242f0d83ecf4d089ff1dbe64747e13d
Autor:
Luiz Gustavo de Almeida Chuffa, Fábio Rodrigues Ferreira Seiva, Adriana Alonso Novais, Vinícius Augusto Simão, Virna Margarita Martín Giménez, Walter Manucha, Debora Aparecida Pires de Campos Zuccari, Russel J. Reiter
Publikováno v:
Molecules, Vol 26, Iss 12, p 3562 (2021)
The use of nanosized particles has emerged to facilitate selective applications in medicine. Drug-delivery systems represent novel opportunities to provide stricter, focused, and fine-tuned therapy, enhancing the therapeutic efficacy of chemical agen
Externí odkaz:
https://doaj.org/article/9a95860c87ff4d2cbae1be1110f7ab97
Autor:
Naiane do Nascimento Gonçalves, Jucimara Colombo, Juliana Ramos Lopes, Gabriela Bottaro Gelaleti, Marina Gobbe Moschetta, Nathália Martins Sonehara, Eva Hellmén, Caroline de Freitas Zanon, Sônia Maria Oliani, Debora Aparecida Pires de Campos Zuccari
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0150407 (2016)
Cancer stem cells (CSCs) have been associated with metastasis and therapeutic resistance and can be generated via epithelial mesenchymal transition (EMT). Some studies suggest that the hormone melatonin acts in CSCs and may participate in the inhibit
Externí odkaz:
https://doaj.org/article/7f2ce1267bc74bebb699e483d3255a0e