Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Deboprosad Mondal"'
Autor:
Mary Lynn Trawick, Tracy E. Strecker, Ernest Hamel, Jeni Gerberich, Deboprosad Mondal, James W. Campbell, Kevin G. Pinney, David J. Chaplin, Haichan Niu, Ralph P. Mason, Debabrata Saha
Publikováno v:
J Med Chem
A promising design paradigm for small-molecule inhibitors of tubulin polymerization that bind to the colchicine site draws structural inspiration from the natural products colchicine and combretastatin A-4 (CA4). Our previous studies with benzocycloa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d617e1f3a9fe6ebf6bb830d99b4a165c
https://doi.org/10.1021/acs.jmedchem.9b00551
https://doi.org/10.1021/acs.jmedchem.9b00551
Autor:
Yuling Deng, Kevin G. Pinney, Deboprosad Mondal, Jacob Ford, Casey J. Maguire, Mary Lynn Trawick
Publikováno v:
The FASEB Journal. 35
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3004828dcdc982244c1d2dc56631e624
https://doi.org/10.1096/fasebj.2021.35.s1.01880
https://doi.org/10.1096/fasebj.2021.35.s1.01880
Autor:
Jeni Gerberich, Ralph P. Mason, Bunnarack Kuch, Blake A. Winn, Mary Lynn Trawick, Zhe Shi, Matthew T. MacDonough, Alejandro J. Ramirez, Tracy E. Strecker, Peter David Davis, Laxman Devkota, Yifan Wang, Ernest Hamel, Deboprosad Mondal, David J. Chaplin, Kevin G. Pinney
Publikováno v:
J Nat Prod
The natural products combretastatin A-1 (CA1) and combretastatin A-4 (CA4) function as potent inhibitors of tubulin polymerization and as selective vascular disrupting agents (VDAs) in tumors. Bioreductively activatable prodrug conjugates (BAPCs) can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c98a96b6fc7d84ea825bc5dbd3a475b3
https://pubmed.ncbi.nlm.nih.gov/32196334
https://pubmed.ncbi.nlm.nih.gov/32196334
Publikováno v:
Tetrahedron Letters. 59:3594-3599
Antibody-drug conjugates (ADCs) represent an emerging class of biopharmaceutical agents that deliver highly potent anticancer agents (payloads) selectively to tumors or components associated with the tumor microenvironment. The linker, responsible fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c11477e7fff3f2fa8eb1a3fc0de48bf1
https://doi.org/10.1016/j.tetlet.2018.08.021
https://doi.org/10.1016/j.tetlet.2018.08.021
Publikováno v:
Tetrahedron letters. 60(5)
Benzosuberene analogues (1 and 2) and dihydronaphthalene analogues (3 and 4) function as potent inhibitors of tubulin polymerization, demonstrate pronounced cytotoxicity (low nM to pM range) against human cancer cell lines, and are promising vascular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a6d98db74817b1998d2334ed82c00ee
https://pubmed.ncbi.nlm.nih.gov/31061544
https://pubmed.ncbi.nlm.nih.gov/31061544
Publikováno v:
European Journal of Organic Chemistry. 2011:7057-7061
Chlorosulfites prepared in situ using thionyl chloride react with nitrile complexes of titanium (IV) fluoride to give a one-pot conversion of alcohols into amides. For the first time, amides are obtained from cyclic alcohols with stereoretention. Cri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::466345f50466fb3d9ede010e1d35dfed
https://doi.org/10.1002/ejoc.201101165
https://doi.org/10.1002/ejoc.201101165
Autor:
Salvatore D. Lepore, Anjan K. Bhunia, Deboprosad Mondal, Shuiyu Lu, Pamela C. Cohn, Song Ye Li, Victor W. Pike
Publikováno v:
The Journal of Organic Chemistry. 74:5290-5296
A series of arylsulfonate nucleophile assisting leaving groups (NALGs) were prepared in which the metal chelating unit is attached to the aryl ring via an ether linker. These NALGs exhibited significant rate enhancements in halogenation reactions usi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01ea40dfb9bb3dd4a51ff6f8dec03ee6
https://doi.org/10.1021/jo900700j
https://doi.org/10.1021/jo900700j
Publikováno v:
Angewandte Chemie. 120:7621-7624
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2904f6d380d2ec947e7d03893fad6260
https://doi.org/10.1002/ange.200802472
https://doi.org/10.1002/ange.200802472
Autor:
Deboprosad Mondal, Salvatore D. Lepore
Publikováno v:
Tetrahedron. 63:5103-5122
Leaving groups have been defined as that part of a substrate that becomes cleaved by the action of a nucleophile.1 The IUPAC definition specifies a leaving group as a molecular fragment (charged or uncharged) that becomes “detached from an atom in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45bee9e383f79ac674e215fcc75b89f3
https://doi.org/10.1016/j.tet.2007.03.049
https://doi.org/10.1016/j.tet.2007.03.049
Autor:
Deboprosad Mondal, Salvatore D. Lepore, Andrea Tafi, Luca Bellucci, Salvatore Guccione, Teodoro Laino, Song Ye Li
Publikováno v:
Journal of organic chemistry 78 (2013): 2118–2127. doi:10.1021/jo3023439
info:cnr-pdr/source/autori:Mondal D. [ 1 ] ; Li S. Y. [ 1 ] ; Bellucci L. [ 2 ] ; Laino T. [ 3 ] ; Tafi A. [ 4 ] ; Guccione S. [ 5 ] ; Lepore S. D. [ 1 ]/titolo:Stereoretentive Chlorination of Cyclic Alcohols Catalyzed by Titanium(IV) Tetrachloride: Evidence for a Front Side Attack Mechanism/doi:10.1021%2Fjo3023439/rivista:Journal of organic chemistry/anno:2013/pagina_da:2118/pagina_a:2127/intervallo_pagine:2118–2127/volume:78
info:cnr-pdr/source/autori:Mondal D. [ 1 ] ; Li S. Y. [ 1 ] ; Bellucci L. [ 2 ] ; Laino T. [ 3 ] ; Tafi A. [ 4 ] ; Guccione S. [ 5 ] ; Lepore S. D. [ 1 ]/titolo:Stereoretentive Chlorination of Cyclic Alcohols Catalyzed by Titanium(IV) Tetrachloride: Evidence for a Front Side Attack Mechanism/doi:10.1021%2Fjo3023439/rivista:Journal of organic chemistry/anno:2013/pagina_da:2118/pagina_a:2127/intervallo_pagine:2118–2127/volume:78
A mild chlorination reaction of alcohols was developed using the classical thionyl chloride reagent but with added catalytic titanium(IV) chloride. These reactions proceeded rapidly to afford chlorination products in excellent yields and with prefere
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c47af1396725b1684efeea162629e86f
https://hdl.handle.net/20.500.11769/14021
https://hdl.handle.net/20.500.11769/14021
