Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Debmalya Bhattacharyya"'
Autor:
Samya Dey, Soumi Basu, Shahena Shah, Debmalya Bhattacharyya, Partha Pratim Gupta, Mahasweta Acharjee, Susanta Roychoudhury, Somsubhra Nath
Publikováno v:
Cancer Treatment and Research Communications, Vol 33, Iss , Pp 100635- (2022)
The course of clinical management in chronic myeloid leukemia (CML) often faces a road-block in the form of front-line (imatinib) therapy resistance. Subsequently, several hotspot mutations were clinically validated in the kinase domain (KD) of BCR-A
Externí odkaz:
https://doaj.org/article/a57c9a4c8b0c48c7b0f88d8930b1ae32
Publikováno v:
Frontiers in Chemistry, Vol 4 (2016)
This review is focused on the structural and physico-chemical aspects of metal cation coordination to G-Quadruplexes (GQ) and their effects on GQ stability and conformation. G-Quadruplex structures are non-canonical secondary structures formed by bot
Externí odkaz:
https://doaj.org/article/d62c84d6a1474e8eae0e88805ef2d236
Publikováno v:
Clinical lymphoma, myelomaleukemia. 21(11)
Introduction Philadelphia chromosome (Ph) marks a group of leukemia with almost all cases of chronic myeloid leukemia (CML), a subset of acute lymphoid leukemia (ALL) and rare cases of acute myeloid leukemia (AML). In the era of precision medicine, s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ebcec10c041d9a3cb8efb6bbebcbf5b
https://pubmed.ncbi.nlm.nih.gov/34400115
https://pubmed.ncbi.nlm.nih.gov/34400115
Autor:
Gaurav Dhingra, Shweta Azad, Uttam Kumar Nath, Debmalya Bhattacharyya, Debranjani Chattopadhya, Aroop Mohanty
Publikováno v:
Drug discoveriestherapeutics. 15(1)
Visceral leishmaniasis (VL), also known as kala-azar (black fever in Hindi), is a disease primarily caused by Leishmania donovani. The most important clinical manifestation of visceral leishmaniasis is fever. Nonspecific laboratory findings of viscer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae722fd7548c956b485c418ada5f8f20
https://pubmed.ncbi.nlm.nih.gov/33612571
https://pubmed.ncbi.nlm.nih.gov/33612571
Publikováno v:
Biochemistry. 53:5461-5470
RNA G-quadruplex (GQ) structures act as regulators of a diverse array of cellular processes including translation, pre-mRNA processing, and mRNA targeting. We report here a strategy of harnessing the natural ability of RNA GQs to inhibit translation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70bbf95a609430462f5a92ffac7eb613
https://doi.org/10.1021/bi5008904
https://doi.org/10.1021/bi5008904
Autor:
Debmalya Bhattacharyya
Publikováno v:
Journal of Scientific Research and Reports. 3:545-552
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a9c02dbe6ba76a4fa6f4a14bbc258bc
https://doi.org/10.9734/jsrr/2014/4044
https://doi.org/10.9734/jsrr/2014/4044
Publikováno v:
Frontiers in Chemistry
Frontiers in Chemistry, Vol 4 (2016)
Frontiers in Chemistry, Vol 4 (2016)
This review is focused on the structural and physicochemical aspects of metal cation coordination to G-Quadruplexes (GQ) and their effects on GQ stability and conformation. G-quadruplex structures are non-canonical secondary structures formed by both
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d75ff94b376efd3e3104ab5e037a0f6e
https://pubmed.ncbi.nlm.nih.gov/27668212
https://pubmed.ncbi.nlm.nih.gov/27668212
Autor:
Debmalya Bhattacharyya, Gayan Mirihana Arachchilage, Soumitra Basu, Mark J. Morris, Katy M. Fedeli, Prakash Kharel
Publikováno v:
Biochimie. 137
RNA domain swapping typically demonstrates conservation of the native function of the domain in a non-native context. In contrast, we employed RNA engineering to demonstrate deviation of G-quadruplex (GQ) function that is contingent upon its context
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40e9d0af8de8137b1c392de1ec9a14d0
https://pubmed.ncbi.nlm.nih.gov/28322930
https://pubmed.ncbi.nlm.nih.gov/28322930
Publikováno v:
Biochemistry. 54(10)
In this study, we report that a 17-nucleotide independently folding RNA G-quadruplex (GQ) domain within the 294-nucleotide human VEGF IRES A interacts with the 40S ribosomal subunit. Footprinting and structure mapping analyses indicate that the RNA G
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfe2d1aa4cd1f8ac574ddcd41b405d1f
https://pubmed.ncbi.nlm.nih.gov/25730526
https://pubmed.ncbi.nlm.nih.gov/25730526
Autor:
Siddhartha Sankar Ray, Soumita Choudhuri, Debmalya Bhattacharyya, Aditi Sen, Maitreyee Bhattacharyya
Publikováno v:
Blood. 126:4572-4572
Introduction: β thalassaemia is a genetic disorder of β globiin gene synthesis. Its presentation ranges from transfusion dependent to non transfusion dependent thalassaemia. Non transfusion dependent thalassaemia can have normal life with proper ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::930d452ab16dd6918348ebd21545c6d0
https://doi.org/10.1182/blood.v126.23.4572.4572
https://doi.org/10.1182/blood.v126.23.4572.4572