Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Debika Biswal Shinohara"'
Autor:
Michael C. Haffner, David M. Esopi, Alcides Chaux, Meltem Gürel, Susmita Ghosh, Ajay M. Vaghasia, Harrison Tsai, Kunhwa Kim, Nicole Castagna, Hong Lam, Jessica Hicks, Nicolas Wyhs, Debika Biswal Shinohara, Paula J. Hurley, Brian W. Simons, Edward M. Schaeffer, Tamara L. Lotan, William B. Isaacs, George J. Netto, Angelo M. De Marzo, William G. Nelson, Steven S. An, Srinivasan Yegnasubramanian
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-17 (2017)
Invasion of malignant cells involves changes in cytoskeleton dynamics. Here the authors identify absent in melanoma 1 as an actin binding protein and show that it regulates cytoskeletal remodeling and cell migration in prostate epithelial cells, acti
Externí odkaz:
https://doaj.org/article/41b0a231505343d098eefebb391e055f
Autor:
Matthew P Vaughn, Debika Biswal Shinohara, Nicole Castagna, Jessica L Hicks, George Netto, Angelo M De Marzo, Traci J Speed, Zachery R Reichert, Bernard Kwabi-Addo, Colin J Henderson, C Roland Wolf, Srinivasan Yegnasubramanian, William G Nelson
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e25707 (2011)
Glutathione S-transferases (GSTs) metabolize drugs and xenobiotics. Yet despite high protein sequence homology, expression of π-class GSTs, the most abundant of the enzymes, varies significantly between species. In mouse liver, hepatocytes exhibit h
Externí odkaz:
https://doaj.org/article/07fb1536d03c43a3a08c8dafe7106551
Autor:
Debika Biswal Shinohara, Angelo M. De Marzo, Karen S. Sfanos, William G. Nelson, Tim N. Mak, Holger Brüggemann, Ajay Vaghasia, Srinivasan Yegnasubramanian, Shu Han Yu
Publikováno v:
Shinohara, D B, Vaghasia, A M, Yu, S-H, Mak, T N, Brüggemann, H, Nelson, W G, De Marzo, A M, Yegnasubramanian, S & Sfanos, K S 2013, ' A mouse model of chronic prostatic inflammation using a human prostate cancer-derived isolate of Propionibacterium acnes ', Prostate . https://doi.org/10.1002/pros.22648
BACKGROUND Prostatic inflammation has been linked to a number of prostatic diseases such as benign prostatic hyperplasia (BPH), prostatitis syndromes, and prostate cancer. Major unanswered questions include what pathogenic mechanisms, such as bacteri
Autor:
Jessica Hicks, Michael C. Haffner, William G. Nelson, Kunhwa Kim, Angelo M. De Marzo, Nicole Castagna, Hong Lam, Paula J. Hurley, Edward M. Schaeffer, Debika Biswal Shinohara, George J. Netto, Alcides Chaux, Meltem Gürel, Tamara L. Lotan, Harrison Tsai, David M. Esopi, William B. Isaacs, Steven S. An, Nicolas Wyhs, Susmita Ghosh, Brian W. Simons, Srinivasan Yegnasubramanian, Ajay Vaghasia
Publikováno v:
Nature Communications
Nature Communications, Vol 8, Iss 1, Pp 1-17 (2017)
Nature Communications, Vol 8, Iss 1, Pp 1-17 (2017)
A defining hallmark of primary and metastatic cancers is the migration and invasion of malignant cells. These invasive properties involve altered dynamics of the cytoskeleton and one of its major structural components β-actin. Here we identify AIM1
Autor:
Debika Biswal Shinohara, Tim N. Mak, Holger Brüggemann, Natalie Fischer, Thomas F. Meyer, Karen S. Sfanos
Publikováno v:
BioMed Research International
Fischer, N, Mak, T N, Shinohara, D B, Sfanos, K S, Meyer, T F & Brüggemann, H 2013, ' Deciphering the intracellular fate of Propionibacterium acnes in macrophages ', BioMed Research International, vol. 2013, pp. 603046 . https://doi.org/10.1155/2013/603046
BioMed Research International, Vol 2013 (2013)
Fischer, N, Mak, T N, Shinohara, D B, Sfanos, K S, Meyer, T F & Brüggemann, H 2013, ' Deciphering the intracellular fate of Propionibacterium acnes in macrophages ', BioMed Research International, vol. 2013, pp. 603046 . https://doi.org/10.1155/2013/603046
BioMed Research International, Vol 2013 (2013)
Propionibacterium acnesis a Gram-positive bacterium that colonizes various niches of the human body, particularly the sebaceous follicles of the skin. Over the last years a role of this common skin bacterium as an opportunistic pathogen has been expl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d82b08900838c5ab47e154d1ef0be266
https://hdl.handle.net/11858/00-001M-0000-0014-9B95-D11858/00-001M-0000-0014-9B97-9
https://hdl.handle.net/11858/00-001M-0000-0014-9B95-D11858/00-001M-0000-0014-9B97-9
Autor:
William G. Nelson, Angelo M. De Marzo, Gretchen K. Hubbard, Debika Biswal Shinohara, Ajay Vaghasia, Karen S. Sfanos, Srinivasan Yegnasubramanian, Shu-Han Yu
Publikováno v:
Cancer Research. 75:5021-5021
Prostate cancer is the second leading cause of cancer death in the U.S. and afflicts 1 in 6 men in their lifetime. Evidence suggests that inflammation contributes to cancer development by causing cellular and genome damage and contributing to a tumor
Autor:
William G. Nelson, Karen S. Sfanos, Ajay Vaghasia, Srinivasan Yegnasubramanian, Angelo M. De Marzo, Shu-Han Yu, Debika Biswal Shinohara
Publikováno v:
Cancer Research. 73:312-312
Background: A causative role for infectious agents and chronic inflammation in prostate cancer etiology has been difficult to establish in humans. To study this potential link in an in vivo system, we have developed a mouse model of long-term bacteri
Autor:
Jessica Hicks, William G. Nelson, Srinivasan Yegnasubramanian, Zachery R. Reichert, Nicole Castagna, George J. Netto, Traci J. Speed, Bernard Kwabi-Addo, Matthew P. Vaughn, Angelo M. De Marzo, Colin J. Henderson, Debika Biswal Shinohara, C. Roland Wolf
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e25707 (2011)
PLoS ONE
PLoS ONE
Background Glutathione S-transferases (GSTs) metabolize drugs and xenobiotics. Yet despite high protein sequence homology, expression of π-class GSTs, the most abundant of the enzymes, varies significantly between species. In mouse liver, hepatocyte