Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Debebe Gebremedhin"'
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0176796 (2017)
The transient receptor potential vallinoid type 4 (TRPV4) is a calcium entry channel known to modulate vascular function by mediating endothelium-dependent vasodilation. The present study investigated if isolated cerebral arterial myocytes of the Faw
Externí odkaz:
https://doaj.org/article/385e69e7e31b472dbed529f94e4c5177
Autor:
Debebe Gebremedhin, Maia Terashvili, Nadi Wickramasekera, David X Zhang, Nicole Rau, Hiroto Miura, David R Harder
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e68498 (2013)
The present study examined the level of generation of reactive oxygen species (ROS) and roles of inactivation of the phosphatase PTEN and the PI3K/Akt signaling pathway in response to an increase in intramural pressure-induced myogenic cerebral arter
Externí odkaz:
https://doaj.org/article/15992cf1532a45d09bae2ddbb2202802
Autor:
Joseph D Thulin, Maia Terashvili, Julian H. Lombard, Kenneth P. Allen, Alison Gifford, Linda A Allen, Kaleigh Kozak, Debebe Gebremedhin
Publikováno v:
J Am Assoc Lab Anim Sci
The present study assessed the effect of nearby construction activity on the responses of rat middle cerebral arteries (MCA)to the endothelium-dependent vasodilator acetylcholine and the NO donor sodium nitroprusside (SNP) and the activity of MaxiK p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::466088d48ae29345918dd496fa147990
https://europepmc.org/articles/PMC7338871/
https://europepmc.org/articles/PMC7338871/
Autor:
Kaleigh Kozak, Maia Terashvili, Debebe Gebremedhin, Nnamdi Uche, Julian H. Lombard, Alison Gifford, Linda A Allen
Publikováno v:
The FASEB Journal. 33
The present study assessed the effect of nearby construction activity on endothelium-dependent vasodilation to acetylcholine (ACh), a crucial diagnostic test, in middle cerebral arteries (MCA) of m...
Publikováno v:
The FASEB Journal. 34:1-1
Publikováno v:
Comprehensive Physiology
There have been numerous reviews related to the cerebral circulation. Most of these reviews are similar in many ways. In the present review, we thought it important to provide an overview of function with specific attention to details of cerebral art
Publikováno v:
The FASEB Journal. 32
Publikováno v:
Current Vascular Pharmacology. 12:810-817
The existence of arterial myogenic tone was first described by Bayliss in 1902, however, its association with pressure-dependent membrane depolarization was not observed until 1984. The factors that mediate myogenic arterial constriction remain unkno
Autor:
David R. Harder, Bruce D. Hammock, Yue Zhang, Raymond C. Koehler, Gina Hong, Adam Sapirstein, Kin Sing Stephen Lee, Debebe Gebremedhin
Publikováno v:
Journal of neurochemistry, vol 140, iss 5
Epoxyeicosatrienoic acids (EETs) are synthesized in astrocytes, and inhibitors of soluble epoxide hydrolase (sEH), which hydrolyzes EETs, reduce infarct volume in ischemic stroke. Astrocytes can release protective neurotrophic factors, such as vascul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b6fbfdd449074f5a38f305b47c715fc
https://europepmc.org/articles/PMC5310989/
https://europepmc.org/articles/PMC5310989/
Autor:
David X. Zhang, Debebe Gebremedhin, Koryn A. Carver, David R. Harder, Nicole Rau, Kevin R. Rarick, Richard J. Roman
Astrocytes secrete vasodilator and vasoconstrictor factors via end feet processes, altering blood flow to meet neuronal metabolic demand. Compared to what is known about the ability of astrocytes to release factors that dilate local cerebral vasculat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2691502ffc80a1a07a4a6f1cbedd73f8
https://europepmc.org/articles/PMC5287377/
https://europepmc.org/articles/PMC5287377/