Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Debbie Wei"'
Publikováno v:
eLife, Vol 4 (2015)
The histone variant H2A.Z is a universal mark of gene promoters, enhancers, and regulatory elements in eukaryotic chromatin. The chromatin remodeler SWR1 mediates site-specific incorporation of H2A.Z by a multi-step histone replacement reaction, evic
Externí odkaz:
https://doaj.org/article/8f0e91433b194013bb69c6068fe0e1d6
Autor:
Jan Wisniewski, Bassam Hajj, Jiji Chen, Gaku Mizuguchi, Hua Xiao, Debbie Wei, Maxime Dahan, Carl Wu
Publikováno v:
eLife, Vol 3 (2014)
The budding yeast centromere contains Cse4, a specialized histone H3 variant. Fluorescence pulse-chase analysis of an internally tagged Cse4 reveals that it is replaced with newly synthesized molecules in S phase, remaining stably associated with cen
Externí odkaz:
https://doaj.org/article/14505f5acebb45bc80145b0d78b135ca
Autor:
Patricia S. Steeg, Lalage M. Wakefield, Dorian B. McGavern, Quentin R. Smith, Imran Khan, Maxwell P. Lee, Simone Difilippantonio, Christina Robinson, Emma L. Dolan, Yuan Yang, Kristine Isanogle, Esra Taner, Debbie Wei, Andy D. Tran, Helen R. Thorsheim, Howard H. Yang, Brunilde Gril, Monika A. Chung, Ramakrishna Samala, Selamawit Gossa, Alex Man Lai Wu
Supplementary Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa994ebca3e494de07a119a575f45f3b
https://doi.org/10.1158/1078-0432.22481523.v1
https://doi.org/10.1158/1078-0432.22481523.v1
Autor:
Patricia S. Steeg, Lalage M. Wakefield, Dorian B. McGavern, Quentin R. Smith, Imran Khan, Maxwell P. Lee, Simone Difilippantonio, Christina Robinson, Emma L. Dolan, Yuan Yang, Kristine Isanogle, Esra Taner, Debbie Wei, Andy D. Tran, Helen R. Thorsheim, Howard H. Yang, Brunilde Gril, Monika A. Chung, Ramakrishna Samala, Selamawit Gossa, Alex Man Lai Wu
Supplementary Table 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa929d4dd5eb4032c9c5cf633602b34a
https://doi.org/10.1158/1078-0432.22481520
https://doi.org/10.1158/1078-0432.22481520
Autor:
Patricia S. Steeg, Lalage M. Wakefield, Dorian B. McGavern, Quentin R. Smith, Imran Khan, Maxwell P. Lee, Simone Difilippantonio, Christina Robinson, Emma L. Dolan, Yuan Yang, Kristine Isanogle, Esra Taner, Debbie Wei, Andy D. Tran, Helen R. Thorsheim, Howard H. Yang, Brunilde Gril, Monika A. Chung, Ramakrishna Samala, Selamawit Gossa, Alex Man Lai Wu
Purpose:Breast cancer diagnosed in young patients is often aggressive. Because primary breast tumors from young and older patients have similar mutational patterns, we hypothesized that the young host microenvironment promotes more aggressive metasta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::243cf2f37e92b609abf3ddbfee1b1f80
https://doi.org/10.1158/1078-0432.c.6530715.v1
https://doi.org/10.1158/1078-0432.c.6530715.v1
Autor:
Patricia S. Steeg, Lalage M. Wakefield, Dorian B. McGavern, Quentin R. Smith, Imran Khan, Maxwell P. Lee, Simone Difilippantonio, Christina Robinson, Emma L. Dolan, Yuan Yang, Kristine Isanogle, Esra Taner, Debbie Wei, Andy D. Tran, Helen R. Thorsheim, Howard H. Yang, Brunilde Gril, Monika A. Chung, Ramakrishna Samala, Selamawit Gossa, Alex Man Lai Wu
Supplementary Figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8455777aa7c40960e5a3425e59f8652d
https://doi.org/10.1158/1078-0432.22481526.v1
https://doi.org/10.1158/1078-0432.22481526.v1
Autor:
Simone Difilippantonio, Christina Robinson, Alexandra S Zimmer, Patricia S. Steeg, Debbie Wei, Michael G. Overstreet, Imran Khan, Brunilde Gril
Publikováno v:
Neuro Oncol
BackgroundBrain metastases of HER2+ breast cancer persist as a clinical challenge. Many therapeutics directed at human epidermal growth factor receptor 2 (HER2) are antibodies or antibody-drug conjugates (ADCs), and their permeability through the blo
Autor:
Lalage M. Wakefield, Patricia S. Steeg, Debbie Wei, Alex Man Lai Wu, Maxwell P. Lee, Dorian B. McGavern, Imran Khan, Andy D. Tran, Kristine A. Isanogle, Monika A. Chung, Quentin R. Smith, Christina Robinson, Selamawit Gossa, Ramakrishna Samala, Emma L. Dolan, Simone Difilippantonio, Yu-an Yang, Howard H. Yang, Helen R. Thorsheim, Brunilde Gril, Esra Taner
Publikováno v:
Clin Cancer Res
Purpose: Breast cancer diagnosed in young patients is often aggressive. Because primary breast tumors from young and older patients have similar mutational patterns, we hypothesized that the young host microenvironment promotes more aggressive metast
Autor:
Jizhong Lou, Zhuqiang Zhang, Zheng Zhou, Guohong Li, Debbie Wei, Hanqiao Feng, Carl Wu, Anand Ranjan, Jicheng Zhao, Xiaoping Liang, Feng Wang, Yingzi Huang, Xuehui Liu, Lu Pan, Qiang Zhong, Li Huang, Shan Shan
Publikováno v:
Nature Structural & Molecular Biology. 23:317-323
Histone variant H2A.Z, a universal mark of dynamic nucleosomes flanking gene promoters and enhancers, is incorporated into chromatin by SRCAP (SWR1), an ATP-dependent, multicomponent chromatin-remodeling complex. The YL1 (Swc2) subunit of SRCAP (SWR1
Autor:
Patricia S. Steeg, Christina Robinson, Quentin R. Smith, Emma Dolan, Dorian B. McGavern, Lalage M. Wakefield, Maxwell P. Lee, Monika Chung, Andy D. Tran, Howard H. Yang, Selamawit Gossa, Kristine A. Isanogle, Alex Man Lai Wu, Debbie Wei, Simone Difilippantonio, Ramakrishna Samala, Helen R. Thorsheim, Brunilde Gril, Yu-an Yang
Publikováno v:
Neuro-oncology Advances
Women diagnosed with breast cancer at a younger age (typically defined as < 40 years old) often have a poorer prognosis and an increased risk of brain metastasis compared to their older counterparts. Multivariate analyses accounting for differences i