Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Debbie M Roeleveld"'
Autor:
Debbie M Roeleveld, Renoud J Marijnissen, Birgitte Walgreen, Monique M Helsen, Liduine van den Bersselaar, Fons A van de Loo, Peter L van Lent, Peter M van der Kraan, Wim B van den Berg, Marije I Koenders
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0171757 (2017)
Th17 cells and their cytokines are linked to the pathogenesis of rheumatoid arthritis, a chronic autoimmune disease characterized by joint inflammation. Th17 development is initiated by combined signaling of TGF-β and IL-6 or IL-21, and can be reduc
Externí odkaz:
https://doaj.org/article/78384ac380dc442c8a8468639da74800
Autor:
Heather L. Evans-Marin, Debbie M. Roeleveld, Shahla Abdollahi-Roodsaz, Jose U. Scher, Sergei B. Koralov, R. Rogier, Marije I. Koenders, Peter M. van der Kraan, Julia Manasson
Publikováno v:
Arthritis & Rheumatology, 70, 12, pp. 1971-1983
Arthritis & Rheumatology (Hoboken, N.j.)
Arthritis & Rheumatology, 70, 1971-1983
Arthritis & Rheumatology (Hoboken, N.j.)
Arthritis & Rheumatology, 70, 1971-1983
Objective Intestinal microbiota are associated with the development of inflammatory arthritis. The aim of this study was to dissect intestinal mucosal immune responses in the preclinical phase of arthritis and determine whether the presence of Th17 c
Autor:
Elly L. Vitters, Marije I. Koenders, Birgitte Walgreen, Peter M. van der Kraan, Jay K. Kolls, Monique M. Helsen, Peter L E M van Lent, Debbie M. Roeleveld, Fons A. J. van de Loo, Joyce Aarts
Publikováno v:
Rheumatology, 60, 4, pp. 1974-1983
Rheumatology (Oxford, England)
Rheumatology, 60, 1974-1983
Rheumatology (Oxford, England)
Rheumatology, 60, 1974-1983
Objective High levels of IL-22 are present in serum and synovial fluid of patients with RA. As both pro- and anti-inflammatory roles for IL-22 have been described in studies using animal models of RA, its exact function in arthritis remains poorly de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f98225dbdfd8c4b4c2a32af12306b06
https://repository.ubn.ru.nl/handle/2066/233614
https://repository.ubn.ru.nl/handle/2066/233614
Autor:
Monique M. Helsen, Joyce Aarts, Marije I. Koenders, Birgitte Walgreen, Debbie M. Roeleveld, Fons A. J. van de Loo, Peter L E M van Lent, Wim B. van den Berg, Elly L. Vitters, Peter M. van der Kraan
Publikováno v:
Abstracts Accepted for Publication.
Background: High interleukin-22 (IL-22) levels are detected in serum and synovial fluid of rheumatoid arthritis (RA) patients. The increased IL-22 serum levels in RA patients correlated positively with multiple clinical disease parameters like diseas
Autor:
Tessa van der Geest, Christian Klein, Tapan K. Nayak, Birgitte Walgreen, Peter Laverman, Martin Hegen, Otto C. Boerman, Marije I. Koenders, Josbert M. Metselaar, Peter M. van der Kraan, Wim B. van den Berg, Gert Storm, Monique M. Helsen, Debbie M. Roeleveld
Publikováno v:
Rheumatology, 57, 4, pp. 737-747
Rheumatology, 57(4), 737-747. Oxford University Press
Rheumatology (Oxford, England), 57(4), 737. Oxford University Press
Rheumatology, 57, 737-747
Rheumatology, 57(4), 737-747. Oxford University Press
Rheumatology (Oxford, England), 57(4), 737. Oxford University Press
Rheumatology, 57, 737-747
Contains fulltext : 191241.pdf (Publisher’s version ) (Closed access) Objectives: RA is a chronic autoimmune disease leading to progressive destruction of cartilage and bone. RA patients show elevated IL-22 levels and the amount of IL-22-producing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bb00df6ed59a3b6d3c09501de1c376a
https://hdl.handle.net/2066/191241
https://hdl.handle.net/2066/191241
Autor:
Heather L. Evans-Marin, R. Rogier, Marije I. Koenders, Debbie M. Roeleveld, Shahla Abdollahi-Roodsaz, Jose U. Scher
Publikováno v:
Oral Presentations.
Background Intestinal microbiota have been associated with psoriatic and rheumatoid arthritis. One of the major effects of microbiota is the induction of mucosal T helper 17 (Th17) cells. We therefore reasoned that the efficiacy of Th17-targeted ther
Autor:
Debbie M Roeleveld, Tessa van der Geest, Birgitte Walgreen, Monique M Helsen, Tapan K Nayak, Christian Klein, Martin Hegen, Peter Laverman, Otto C Boerman, Marije I Koenders
Publikováno v:
New players and novel targets in inflammation.
Autor:
Monique M. Helsen, Renoud J. Marijnissen, Wim B. van den Berg, Debbie M. Roeleveld, Birgitte Walgreen, Peter L E M van Lent, Peter M. van der Kraan, Marije I. Koenders, Liduine van den Bersselaar, Fons A. J. van de Loo
Publikováno v:
PLoS One, 12, 2
PLoS One, 12
PLoS ONE, Vol 12, Iss 2, p e0171757 (2017)
PLoS ONE
PLoS One, 12
PLoS ONE, Vol 12, Iss 2, p e0171757 (2017)
PLoS ONE
Contains fulltext : 173198.pdf (Publisher’s version ) (Open Access) Th17 cells and their cytokines are linked to the pathogenesis of rheumatoid arthritis, a chronic autoimmune disease characterized by joint inflammation. Th17 development is initiat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9ba9bd335fcbed5ce2472c6c070ec71
https://hdl.handle.net/2066/173198
https://hdl.handle.net/2066/173198
Autor:
Wim B. van den Berg, Cheryl Nickerson-Nutter, Fons A. J. van de Loo, Renoud J. Marijnissen, Deborah Young, Sabrina Garcia de Aquino, Annemieke M. H. Boots, Debbie M. Roeleveld, Shahla Abdollahi-Roodsaz, Annemiek B. van Spriel, Marije I. Koenders
Publikováno v:
Arthritis & Rheumatology. 66:886-895
OBJECTIVE: The cytokine interleukin-21 (IL-21) can have both proinflammatory and immunosuppressive effects. The purpose of this study was to investigate the potential dual role of IL-21 in experimental arthritis in relation to Th17 cells. METHODS: An
Autor:
Peter M. Hoogerbrugge, Hanka Venselaar, Debbie M. Roeleveld, C Lanvers, Laurens T. van der Meer, Frank N. van Leeuwen, Marloes Levers, Joachim Boos, Esmé Waanders, Roger J. M. Brüggemann, Roland P. Kuiper, D. Maroeska te Loo
Publikováno v:
Blood, 124, 3027-9
Blood, 124, 19, pp. 3027-9
Blood, 124(19), 3027-3029. American Society of Hematology
Blood, 124, 19, pp. 3027-9
Blood, 124(19), 3027-3029. American Society of Hematology
To the editor: l-Asparaginase (ASNase) is a key component of protocols used to treat acute lymphoblastic leukemia (ALL). Poorly understood interpatient differences in ASNase pharmacokinetics demand therapeutic drug monitoring to prevent patients from