Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Debbie Kefauver"'
Autor:
Debbie Kefauver, John W. Huggins, Mark J. Martinez, Elizabeth A. Thompson, Donald F. Smee, Mike Bray
Publikováno v:
The Journal of Infectious Diseases. 181:10-19
The efficacy of cidofovir for treatment of cowpox virus infection in BALB/c mice was investigated in an effort to evaluate new therapies for virulent orthopoxvirus infections of the respiratory tract in a small animal model. Exposure to 2(-5)x10(6) p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::431a1d35bf6b3af084e677d04dcf55eb
https://doi.org/10.1086/315190
https://doi.org/10.1086/315190
Autor:
John W. Huggins, M. A. Ussery, L. Barthel‐Rosa, Debbie Kefauver, B. Gabrielsen, T. P. Monath, G N Chmurny, C See, E. M. Schubert, M. J. Phelan
Publikováno v:
Journal of Medicinal Chemistry. 35:3231-3238
Ten, hitherto unreported, analogues of 1-beta-D-ribofuranosyl-1,2,4-triazole-3-carboxamidine hydrochloride (2a, ribamidine) and methyl carboximidate 5 have been synthesized. These include the N-cyano (2b), N-alkyl (2c-e), N-amino acid (2f-h), N,N'-di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f9f4148ddba5653d91b3b0d76839d1b
https://doi.org/10.1021/jm00095a020
https://doi.org/10.1021/jm00095a020
Publikováno v:
Antimicrobial agents and chemotherapy. 46(5)
Cidofovir {[(S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine] [HPMPC]}-resistant forms of camelpox, cowpox, monkeypox, and vaccinia viruses were developed by prolonged passage in Vero 76 cells in the presence of drug. Eight- to 27-fold-higher conc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c0333ced53c06c6b3eeaf5bdb76768e
https://pubmed.ncbi.nlm.nih.gov/11959564
https://pubmed.ncbi.nlm.nih.gov/11959564